BB D-1

Question 1

What type of serological testing does the blood bank technologist perform when determining the blood group of a patient?

Answer 1

PHENOTYPING

Question 2

Which genotype(s) will give rise to the Bombay phenotype?

Answer 2

hh only

Question 3

Which of the following describes the expression of most blood group antigens?

Answer 3

CODOMINANT

Question 4

What blood type is not possible for an offspring of an AO and BO mating?

Answer 4

AB, A, B, O

Question 5

A patient’s serum is incompatible with O cells. The patient RBCs give a negative reaction to anti-H lectin. What is the most likely cause of these results?

Answer 5

THE PATIENT MAY BE A BOMBAY

Question 6

What antibodies are formed by a Bombay individual?

Answer 6

ANTI-A, ANTI-B, AND ANTI-H

Question 7

Acquired B antigens have been found in

Answer 7

GROUP A PERSONS

Question 8

Which typing results are most likely to occur when a patient has an acquired B antigen?

Answer 8

Anti-A 4+, anti-B 1+, A1 cells neg, B cells 4+

Question 9

Which blood group has the LEAST amount of H antigen?

Answer 9

A1B

Question 10

What should be done if all forward and reverse ABO results are negative?

Answer 10

Incubate at 22°C or 4°C to enhance weak expression

Question 11

N-acetyl-D-galactosamine is the immunodominant carbohydrate that reacts with:

Answer 11

Dolichos biflorus

Question 12

A stem cell transplant patient was retyped when she was transferred from another hospital. What is the most likely cause of the following results?

Answer 12

IMMUNODEFICIENCY

Question 13

A complete Rh typing for antigens C, c, D, E, and e revealed negative results for C, D, and E. How is the individual designated?

Answer 13

Rh NEGATIVE

Question 14

A patient tests positive for weak D but also appears to have anti-D in his serum. What may be the problem?

Answer 14

A D mosaic may make antibodies to missing antigen parts

Question 15

What does the genotype —/— represent in the Rh system

Answer 15

Rh NULL

Question 16

What techniques are necessary for weak D testing?

Answer 16

37°C incubation + indirect antiglobulin test

Question 17

Which of the following sugars must be present on a precursor substance for A and B antigenic activity to be expressed?

Answer 17

L-FUCOSE

Question 18

Lectins are useful in determining the cause of abnormal reactions in blood bank serology. These lectins are frequently labeled as anti-H, anti-A1 etc. The nature of these lectins is explained by which of the following?

Answer 18

A plant substance that chemically reacts with certain RBC antigens

Question 19

If a patient has the Rh genotype DCe/DCe and receives a unit of red blood cells from a DCe/dce individual, what Rh antibody might the patient develop?

Answer 19

ANTI-c

Question 20

Which of the blood group systems is associated with antibodies that are generally IgM?

Answer 20

LEWIS

Question 21

Associated with Group 1 ABO discrepancies

Answer 21

Subgroups of A or B

Question 22

An antigen present on most D-positive and all C-positive RBCs:

Answer 22

G

Question 23

From the following ABO mating, what are the probabilities of the ABO PHENOTYPES of potential offspring? Mother: Group O; Father: Group B (heterozygous).

Answer 23

50% B, 50% O

Question 24

Rh antibodies are predominantly

Answer 24

IgG

Question 25

Rh immune globulin provides ____ protection against fetal D antigen.

Answer 25

PASSIVE

Question 26

If an Rh negative woman recently delivered an Rh positive baby and the Kleihauer-Betke test result is 5%, how many vials of Rh Ig should be administered?

Answer 26

9

Question 27

The glass surface of an Rh viewbox should be _____ C.

Answer 27

BETWEEN 45 and 50C

Question 28

Anti-c can be formed by persons with the genotype

Answer 28

R1R1

Question 29

The results of a Kleihauer-Betke stain indicate a feto-maternal hemorrhage of 35 mL of whole blood. How many vials of Rh immune globulin would be required?

Answer 29

2

Question 30

ABH substances would be found in the saliva of a group B secretor:

Answer 30

B and H

Question 31

The immunogenicity of the common Rh antigens may be described from greatest to least:

Answer 31

D>c>E>C>e

Question 32

An individual with genes A, H, Se and lele has which of the following phenotypes?

Answer 32

AH, Le (a-b-)

Question 33

The antigen system closely associated phenotypically with Rh is known as:

Answer 33

LW

Question 34

“O” secretor person would demonstrate what substance/s in his saliva:

Answer 34

H

Question 35

Which of the following is NOT true about the anti-A and anti-B?

Answer 35

They are well-developed at birth

Question 36

What chain is formed when the terminal galactose on the ABH precursor substance is attached to the N-acetylglucosamine in beta 1, 4 linkage?

Answer 36

Type 2 precursor chain

Question 37

Rh-HDN occurs in what type of mother and child

Answer 37

Mother is Rh (-), child is Rh (+)

Question 38

ABO antibodies in infants are detected in serum:

Answer 38

3 to 6 months after birth

Question 39

Which cells agglutinate most strongly with Ulex europaeus lectin?

Answer 39

O

Question 40

If a patient has an A2 ABO type, which of the following statements is true?

Answer 40

The patient’s serum will react with A1 cells if anti-A1 is present

Question 41

Of the red cells listed, which has the most D antigen present?

Answer 41

D- - / D - -

Question 42

A trauma patient with type AB is seen at a rural hospital. The hospital only has 3 units of type AB RBCs. What blood type of RBCs can the patient receive as an alternative?

Answer 42

A, B, O

Question 43

If a person has the genetic makeup Hh, AO, LeLe, sese, what substance will be found in the secretions?

Answer 43

Lea SUBSTANCE

Question 44

Anti-E will react with which of the following cells?

Answer 44

R2R2

Question 45

Rh antibodies react best at what temperature (°C)?

Answer 45

37C

Question 46

Which of the following is the most common haplotype in the ASIAN population?

Answer 46

DCe

Question 47

If a patient who is R1R1 is transfused with RBCs that are Ror, which antibody is he most likely to produce?

Answer 47

ANTI-c

Question 48

Which of the following characteristics best describes Lewis antibodies?

Answer 48

IgM, naturally occurring, do not cause HDN

Question 49

Transformation to Leb phenotype after birth may be as follows:

Answer 49

Le(a–b–) to Le(a+b–) to Le(a+b+) to Le(a–b+)

Question 50

Transformation to Leb phenotype after birth may be as follows:

Answer 50

Le(a–b–) to Le(a+b–) to Le(a+b+) to Le(a–b+)