BB D-4

Question 1

What is the component of choice for someone who needs a RBC transfusion when there is a history of febrile transfusion reactions?

Answer 1

Leukocyte-reduced RBCs

Question 2

Which of the following is acceptable to be given intravenously with a blood transfusion?

Answer 2

Physiologic saline

Question 3

Hemolytic transfusion reactions are the most serious type of reactions to blood transfusion. The majority of hemolytic transfusion reactions are caused by ____ errors.

Answer 3

CLERICAL

Question 4

Occasionally, patients have an anaphylactic reaction to a specific immunoglobulin class during a transfusion. Which immunoglobulin class is most often implicated?

Answer 4

IgA

Question 5

A transfusion reaction is reported by the nursing unit on patient. The nurse reports that the patient had chills, fever, and back pain within a few minutes of starting the unit. The nurse asks what s/he should do.

Answer 5

Discontinue the unit, keep the line open

Question 6

All paperwork checks on this transfusion reaction are OK. The pretransfusion sample has straw-colored plasma. The post-transfusion sample has RED-tinged plasma. This is indicative of a(an):

Answer 6

Intravascular transfusion reaction

Question 7

A patient experiences severe rigors and goes into shock after receiving part of a unit of RBC. The patient’s temperature, which was 37.5°C pretransfusion, is now 40.0°C. Which of the following is the most likely type of reaction?

Answer 7

SEPTIC

Question 8

Which is the class of immunoglobulin uniquely associated with hemolytic disease of the newborn (HDN)?

Answer 8

IgG

Question 9

What is the principle of the Kleihauer-Betke stain?

Answer 9

Adult hemoglobin is more soluble in acid buffer than fetal hemoglobin.

Question 10

The temperature of a blood refrigerator without a continuous recording device should be recorded:

Answer 10

EVERY 4 HRS

Question 11

When should quality control be performed on routine blood typing reagents?

Answer 11

ONCE DAILY

Question 12

Kernicterus is caused by the effects of:

Answer 12

Unconjugated bilirubin

Question 13

All of the following are routinely performed on a cord blood sample except:

Answer 13

ANTIBODY SCREEN

Question 14

A patient had a transfusion reaction to packed red blood cells. The medical laboratory scientist began the laboratory investigation of the transfusion reaction by assembling pre- and post-transfusion specimens and all paperwork and computer printouts. What should he do next?

Answer 14

Check for a clerical error(s)

Question 15

What may be found in the serum of a person who is exhibiting signs of TRALI (transfusion-related acute lung injury)?

Answer 15

Antileukocyte antibody

Question 16

Which type of transfusion reaction occurs in about 1% of all transfusions, results in a temperature rise of 1°C or higher, is associated with blood component transfusion, and is not related to the patient’s medical condition?

Answer 16

Febrile nonhemolytic reaction

Question 17

What would be the result of group A blood given to an O patient?

Answer 17

Immediate hemolytic transfusion reaction

Question 18

What component is most frequently involved with transfusion-associated sepsis?

Answer 18

PLATELETS

Question 19

Fatal transfusion reactions are mostly caused by?

Answer 19

CLERICAL ERRORS

Question 20

Pain at infusion site and hypotension are observed with what type of reaction?

Answer 20

Acute hemolytic transfusion reaction

Question 21

Irradiation of blood is performed to prevent?

Answer 21

Transfusion-associated graft-versus-host disease

Question 22

The only presenting sign most often accompanying a delayed hemolytic transfusion reaction is?

Answer 22

Unexplained decrease in hemoglobin

Question 23

Which transfusion reaction presents with fever, maculopapular rash, watery diarrhea, abnormal liver function, and pancytopenia?

Answer 23

Transfusion-associated graft-versus-host disease

Question 24

Characteristic of iron overload

Answer 24

DELAYED, NONIMMUNE COMPLICATION
CHELATING AGENTS ARE USED
MULTIORGAN DAMAGE MAY OCCUR

Question 25

Which of the following tests is useful to confirm that a patient or donor is infected with HCV?

Answer 25

RIBA

Question 26

The first retrovirus to be associated with human disease was:

Answer 26

HTLV-I

Question 27

What is the most common parasitic complication of transfusion?

Answer 27

PLASMODIUM SPECIES

Question 28

The endpoint of the gel test is detected by:

Answer 28

AGGLUTINATION

Question 29

The endpoint of the  SPRCA test is detected by:

Answer 29

Attachment of indicator cells

Question 30

An advantage for both gel and solid-phase technology is:

Answer 30

STANDARDIZATION

Question 31

Incubation period for the gel test

Answer 31

15 MINS

Question 32

Centrifugation time for the test:

Answer 32

10 MINS

Question 33

An important determinant of platelet viability following storage is:

Answer 33

PLASMA PH

Question 34

Irradiation of a unit of Red Blood Cells is done to prevent the replication of donor:

Answer 34

LYMPHOCYTES

Question 35

The Liley method of predicting the severity of hemolytic disease of the newborn is based on the amniotic fluid:

Answer 35

Change in optical density measured to 450 nm

Question 36

Kernicterus is caused by the effects of:

Answer 36

Unconjugated bilirubin

Question 37

Blood for intrauterine transfusion should be all of the following, EXCEPT:

Answer 37

More than 7 days old

Question 38

RhIG is indicated for:

Answer 38

Mothers who are Rh-negative

Question 39

Which of the following is the preferred specimen for the initial compatibility testing in exchange transfusion therapy?

Answer 39

Maternal serum

Question 40

Posttransfusion purpura (PTP) is usually caused by:

Answer 40

Anti-HPA

Question 41

In a delayed transfusion reaction, the causative antibody is generally too weak to be detected in routine compatibility testing and antibody screening tests, but is typically detectable at what point after transfusion?

Answer 41

3 TO 7 DAYS

Question 42

Which of the following transfusion reactions is characterized by high fever,  shock, hemoglobinuria, DIC and renal failure?

Answer 42

BACTERIAL CONTAMINATION

Question 43

Hemoglobinuria, hypotension and generalized bleeding are symptoms of which of the following transfusion reactions?

Answer 43

HEMOLYTIC

Question 44

The MOST COMMON INITIAL clinical manifestation of a hemolytic transfusion reaction is:

Answer 44

FEVER

Question 45

Leukocyte-poor red blood cells would most likely be indicated for patients with a history of:

Answer 45

Febrile nonhemolytic transfusion reaction

Question 46

Hives and itching are symptoms of which of the following transfusion reactions?

Answer 46

ALLERGIC

Question 47

The laboratory assay of brain natriuretic peptide (BNP) may be used to aid in the diagnosis of:

Answer 47

TACO

Question 48

The most common isolate found in RBC units

Answer 48

Yersinia enterocolitca

Question 49

Organisms most frequently recovered from donated blood and contamination of platelets:

Answer 49

Staphylococcus epidermidis, Bacillus cereus

Question 50

Congestive heart failure, severe headache and/or peripheral edema occurring soon after transfusion is indicative of which type of transfusion reaction?

Answer 50

Circulatory overload

Question 51

The most frequent transfusion-associated disease complication of blood transfusion is:

Answer 51

HEPATITIS