Begnin Mesenchymal Tumors

Question 1

Lesion is categorized border line tumor

Answer 1

Chondroma

Question 2

Why chondroma is called border line tumor

Answer 2

Because its like well diferentiated type of chondrosarcoma

Question 3

Site of chondroma

Answer 3

Anterior maxilla، posterior manduble، symphysis menti , coronoid process ,condyle

Question 4

Hp of chondroma

Answer 4

Lobules of mature hyaline cartilage

Question 5

Most common site of osteoma

Answer 5

Skull

Question 6

Site of periosteal osteoma ,but site of endosteal osteoms

Answer 6

Surface of bone
Intrabony

Question 7

RF of osteoma

Answer 7

Well circumscribed radioopaue mass

Question 8

Types of osteomas Hp

Answer 8

Compact dense bone with minimal marrow tissue
Cancellous : bone trabeculae

Question 9

What is Choriostoma?

Answer 9

A tumor-like growth of normal tissue in an abnormal location, typically near the foramen cecum.

Question 10

Where is Choriostoma commonly found?

Answer 10

In the tongue, mainly in the posterior third.

Question 11

What are the symptoms of Choriostoma?

Answer 11

Asymptomatic except for gagging, dysphagia, and speaking difficulty.

Question 12

What is the composition of Choriostoma?

Answer 12

Dense lamellar bone and mature cartilage, surrounded by dense fibrous connective tissue.

Question 13

What is Gardner syndrome?

Answer 13

An autosomal dominant trait characterized by multiple intestinal polyps and other features.

Question 14

What are the key features of Gardner syndrome?

Answer 14

Multiple intestinal polyps, epidermoid and sebaceous cysts, desmoid tumors, adrenal gland tumors, supernumerary teeth, and pigmented lesions on ocular fundus.

Question 15

What are the types of tumors associated with Gardner syndrome?

Answer 15

Desmoid tumors and adrenal gland tumors.

Question 16

What dental abnormalities are associated with Gardner syndrome?

Answer 16

Supernumerary teeth and impacted teeth.
ملحوظة : نقص الأسنان مع ectodermal dysplasia syndrome

Question 17

What type of cysts are associated with Gardner syndrome?

Answer 17

Epidermoid and sebaceous (epithelial) cysts.

Question 18

What is CHRPE?

Answer 18

Pigmented lesions on the ocular fundus associated with Gardner syndrome.

Question 19

What are the key features of Neurofibromatosis type 1?

Answer 19

1. Café au lait macules.
2. Neurofibromas.
3. Freckling in axillary or inguinal regions (Crowe’s sign).
4. Two or more iris hamartomas (Lisch nodules) -> brown pigmented spots in the iris.
5. Optic glioma.
6. Bone changes → thinning of long bone cortex.
7. First degree relative diagnosed with neurofibromatosis type 1.

Question 20

What is a granular cell tumor?

Answer 20

A soft tissue tumor originating from Schwann cells, composed of large cells with eosinophilic, granular cytoplasm.

Very rare, benign soft tissue tumor.

Question 21

What is the most Histopathological feature of granular cell tumor (schwannoma)

Answer 21

Cells : syntial pattern
Cytoplasm : abundant cytoplasm with coarse granules (representing phagolysosmes )

Pseudocarcinomatus appearance(pseudoepithelimatus hyperplasia)

Question 22

Lesion شبه ال granular cell tumor(granular cell scwanoma) وبتيجي مع ال new born

Answer 22

Congenital epulis of new born

Question 23

Age ,site of congenital epulis newborn

Answer 23

New born
Anterior alveolar ridge of maxilla,and madible usually canine lateral incisor

Question 24

Hp of congenital epulis of new born

Answer 24

Epithelium :atrophic
No pseudoepithelimatus appearance
Negative to s100

Question 25

What is the Site of traumatic meuroma ?

Question 26

Other name of neurolemmoma

Question 27

Neurolemmoma is associated with which syndrome

Question 28

What is the Hp of neurolemmoma?

Question 29

What is the difference between Antoni A and antoni B

Question 30

What is the definition of of verocay bodies ?and associated with each lesion ?

Question 31

Neurofibroma is associated with which syndrome?

Question 32

What are the components of neurofibroma?

Question 33

What is the shape of collagen bundles in neurofibroma?

Answer 33

Shredded carrot collagen

Question 34

Is fibroma capsulated?

Answer 34

False

Question 35

The most common bengin neoplasm of oral cavity

Answer 35

Fibroma

Question 36

If fibroma reactive to secondary irritation is called

Answer 36

Irritational,traumatic ,focal fibrous hyperpla6

Question 37

What is Giant Cell Fibroma?

Answer 37

A benign, sessile or pedunculated lesion of oral mucosa seen predominately in the third decades of life with a slight female predilection. ## Footnote It presents as a localized reactive proliferation of fibrous tissue, resembling irritation fibroma rather than a neoplastic proliferation.

Question 38

What characterizes the cells in Giant Cell Fibroma?

Answer 38

The presence of large stellate-shaped, sometimes multinucleated fibroblasts that tend to occur near the overlying epithelium. ## Footnote The surface epithelium is thin with narrow elongated rete ridges.

Question 39

What is Fibrous Histiocytoma?

Answer 39

A benign fibrohistocytic tumor that arises within the subcutaneous or deep soft tissues and rarely metastasizes. ## Footnote BFH is reported at any age with predominance in males adults older than 25 years and with a mean age of 40 years.

Question 40

What are the clinical features of oral BFH?

Answer 40

Painless solitary tumor, slowly enlarging. ## Footnote The tumor typically does not cause discomfort or pain.

Question 41

What is the histological appearance of Fibrous Histiocytoma?

Answer 41

spindle shaped fibroblasts in a storiform pattern intermixed with rounded histiocyte-like cells. ## Footnote Multinucleated giant cells and scattered lymphocytes may also be present.

Question 42

True or False: Giant Cell Fibroma is a neoplastic proliferation.

Answer 42

False. ## Footnote It is a localized reactive proliferation rather than a neoplastic growth.

Question 43

Fill in the blank: Giant Cell Fibroma resembles _______ rather than a neoplastic proliferation.

Answer 43

irritation fibroma. ## Footnote The resemblance indicates its reactive nature.

Question 44

What age group is predominantly affected by Fibrous Histiocytoma?

Answer 44

Adults older than 25 years, with a mean age of 40 years. ## Footnote There is a noted predominance in males.

Question 45

What is a lipoma?

Answer 45

A benign lesion composed largely of fat tissue ## Footnote Lipomas are one of the most common neoplasms but are rarely seen in the oral cavity.

Question 46

In which demographic are oral lipomas more commonly found?

Answer 46

More often in males than in females, particularly in patients past the age of 40 years ## Footnote This demographic trend highlights the age and gender predisposition for the occurrence of oral lipomas.

Question 47

What is the most common site for oral lipomas?

Answer 47

The cheek ## Footnote Oral lipomas can occur at any site but the cheek is the predominant location.

Question 48

What is the histopathological characteristic of a lipoma?

Answer 48

Lobular mass of mature fat cells with collagen in between ## Footnote This histopathological structure is typical for lipomas.

Question 49

What appearance do fat cells in a lipoma have?

Answer 49

Characteristic signet ring appearance ## Footnote This distinctive appearance aids in the identification of lipomas during histopathological examination.

Question 50

What does significant fibrous tissue in a lipoma give rise to?

Answer 50

Fibro-lipoma ## Footnote The presence of fibrous tissue alters the classification of the lipoma.

Question 51

What is formed when the endothelial element is obvious in a lipoma?

Answer 51

Angiolipoma ## Footnote Angiolipomas are a variant of lipomas characterized by more vascular components.

Question 52

When does Strawberry hemangioma typically present?

Answer 52

At birth or within a few weeks ## Footnote Strawberry hemangiomas can appear immediately at birth or shortly after, distinguishing them from other types.

Question 53

When do Infantile hemangiomas typically appear?

Answer 53

Within a month after birth ## Footnote Unlike Strawberry hemangiomas, Infantile hemangiomas manifest after birth.

Question 54

What is a common characteristic of both Strawberry and Infantile hemangiomas?

Answer 54

They often show self involution ## Footnote Both types of hemangiomas are known to regress on their own over time.

Question 55

What may larger hemangiomas require?

Answer 55

Surgical excision ## Footnote Larger lesions that do not involute may need to be surgically removed.

Question 56

What is the histology of Capillary Hemangioma?

Answer 56

Proliferation of small blood vessels ## Footnote Capillary hemangiomas are characterized by a dense network of small blood vessels.

Question 57

What is the histology of Cavernous Hemangioma?

Answer 57

Proliferation of large blood vessels and communicating with each other ## Footnote Cavernous hemangiomas consist of larger vascular channels that are interconnected.