Pigmemted Lesions

Question 1

Origin of melanocytes

Answer 1

Neural crest cells

Question 2

Site of melanocytes

Answer 2

.

Question 3

Mechanism of melanin formation

Answer 3

Tyrosine dopa ,melanin by tyrosinase and activation of MSH

Question 4

Number melanocytes

Answer 4

.

Question 5

Pigmemted nevi (anthoer nsme , behaviour

Answer 5

Melanicytic nevi , begnin

Question 6

Difference between nevi cells, melanocytes

Answer 6

Small
Without dentritces
Arranged in groups
Less metabolic active

Question 7

Types of nevi

Answer 7

.

Question 8

Variant of melanoctyic nevi

Answer 8

Blue nevi

Question 9

Pigmemted nevi most common in the ……

Answer 9

In the skin

Question 10

Most dangerous nevi

Answer 10

Junctional

Question 11

Site of juctional nevi

Answer 11

…

Question 12

Describe cells of compound nevi that reach derm

Answer 12

Loss ability and power

Question 13

Most common nevi

Answer 13

Intradermal

Question 14

Site ,shape of cells in blue nevi

Answer 14

Deep
Spindle cells

Question 15

What is 2-Hypodontia?

Answer 15

Failure of development of one or two teeth

Is hereditary condition

Question 16

Which teeth are most commonly affected by 2-Hypodontia?

Answer 16

• 3rd molars
• 2nd mandibular molars
• Maxillary lateral incisors
• Maxillary 2nd premolars

These are the most frequently missing teeth in this condition.

Question 17

Is 2-Hypodontia hereditary?

Answer 17

Yes

This condition has a genetic basis.

Question 18

Front

Answer 18

Back

Question 19

What are nevus cells?

Answer 19

Altered melanocytes that are smaller, lack dendrites, and are less metabolically active.

Question 20

What are the three main types of acquired melanocytic nevi?

Answer 20

Junctional, compound, and intradermal nevi.

Question 21

What defines a junctional nevus histologically?

Answer 21

Nests of nevus cells at the dermo-epidermal junction.

Question 22

Why do junctional nevi have malignant potential?

Answer 22

Nevus cells at the junction are metabolically active and capable of proliferation.

Question 23

What is a compound nevus?

Answer 23

A nevus with both junctional and intradermal elements.

Question 24

What happens to nevus cells when they migrate into the dermis?

Answer 24

They become smaller, lose melanin-synthesizing enzymes, and lose proliferative potential.

Question 25

What is the most common type of intraoral nevus?

Answer 25

Intradermal nevus (also called intramucosal nevus).

Question 26

Describe a blue nevus.

Answer 26

A flat bluish lesion with spindle-shaped nevus cells located deep in the dermis.

Question 27

Which type of nevus is more likely to become malignant?

Answer 27

Dysplastic nevi.

Question 28

What clinical signs suggest malignant transformation of a nevus?

Answer 28

Rapid enlargement, ulceration, color change, and lymph node enlargement.

Question 29

What is melanoma?

Answer 29

A malignant tumor arising from melanocytes.

Question 30

Which growth pattern in melanoma is associated with better prognosis?

Answer 30

Radial growth pattern.a=superficial spreading

Question 31

Which growth pattern in melanoma is associated with a poor prognosis?

Answer 31

Vertical growth pattern.=nodular spreading

Question 32

Name the four clinical types of melanoma.

Answer 32

Lentigo maligna melanoma, superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma.

Question 33

Which melanoma type is most common on sun-exposed skin of the face?

Answer 33

Lentigo maligna melanoma.

Question 34

Which is the most common type of skin melanoma?

Answer 34

Superficial spreading melanoma. افتكر اقلهم خطورة واكثرهم وجودا

Question 35

What characterizes nodular melanoma?

Answer 35

Dark pigmented elevation with vertical growth from the beginning, poor prognosis.

Question 36

Which melanoma type is more common orally in Black individuals?

Answer 36

Acral lentiginous melanoma.

Question 37

What histological patterns are seen in melanoma?

Answer 37

Rounded cell groups in fibrous stroma or sarcomatous spindle-cell patterns.

Question 38

How does melanoma metastasize?

Answer 38

Through local invasion, lymphatics to regional nodes, and via blood to lungs and other organs.

Question 39

Shape of cells of melanoma

Answer 39

Rounded cells Or sacrcomatus spindle cell pattern