Benign Breast Conditions Flashcards

(46 cards)

1
Q

most common breast lesion

A

fibrocytic change

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2
Q

ill defined thickening/lumpiness of breast in female 40-55 yrs.
most likely?

A

fibrocytic change

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3
Q

microscopic appearance of fibrocystic change

A

combination of cyst formation, apocrine metaplasia, fibrosis, epithelial proliferation

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4
Q

describe the cysts in fibrocystic change

A

localised dilatation of lobular + terminal ductules
multiple + <1cm
thin walled
blue appearance on microscope

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5
Q

presentation of fibrocystic change

A

ill defined thickening/lumpiness

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6
Q

painless, firm, mobile mass in female <30

most likely?

A

fibroadenoma

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7
Q

pathology of fibroadenoma

A

localised hyperplasia – well defined mass

- proliferation of intralobular stroma

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8
Q

who is fibroadenoma common in

A

young females

more common in africans

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9
Q

what is a tubular adenoma

A

benign circumscribed lesion

similar presentation to fibroadenoma

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10
Q

who gets a tubular adenoma

A

30-40 year olds

40% related to pregnancy

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11
Q

what is a hamartoma

A

disordered collection of lobules, stroma + fat

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12
Q

presentation of hamartoma

A

well defined mass - often impalpable + detected by mammogram
can occur at any age but more common pre menopause

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13
Q

presentation of sclerosis adenosis

A

often detected by mammogram

but can present as pain, tenderness, lumpiness/thickening

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14
Q

sclerosis adenosis on mammogram

A

microcalcification - can be mistaken for invasive carcinoma

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15
Q

appearance of a radial scar on mammogram

A

spiculate mass

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16
Q

pathology of radial scar

A

central fibrous scarring + entrapped tubular structures

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17
Q

presentation of duct papilloma

A

nipple discharge - might be blood stained

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18
Q

describe a central duct papilloma

A

usually larger, single, occurs in main nipple ducts

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19
Q

describe a peripheral duct papilloma

A

smaller, multiple, associated with hyperplasia

– increased risk of carcinoma

20
Q

presentation of phyllodes tumour

A

fast growing, unilateral well defined mass.

middle aged-elderly females

21
Q

microscopic appearance of phyllodes tumour

A

‘leaf like’ clefts of epithelium

22
Q

most common organism in acute pyogenic mastitis

23
Q

most common cause of acute pyogenic mastitis

A

lactation – infection via ducts/abrasion of the nipple

24
Q

Tx of acute pyogenic mastitis

A

send them home with hot compress + encourage breast feeding
give flucloxacillin if not improved with 24 hours
percutaneous drainage if abscess

25
presentation of TB in the breast
caeseating lesion
26
presentation of duct ectasia
nipple discharge -bloody and/or purulent
27
pathology of duct ectasia
dilatation of ducts containing foamy macrophages + surrounding chronic infiltrate + periductal fibrosis
28
feels like a 'bag of worms'
duct ectasia
29
what is duct ectasia associated with
smoking
30
what is a galactocele
cystic swelling of a lactiferous duct that develops during lactation NOT PAINFUL
31
what is contained in a galactocele
contains creamy, lipid rich fluid that gradually becomes watery
32
Tx of galactocele
drainage via FNA
33
who are breast abscesses most common in
lactating postpartum women
34
presentation of abscess
tenderness, pain, swelling
35
Tx of breast abscess
drainage with no.18 gauge needle - repeat every 3 days if >10ml pus - flucloxacillin
36
what is periductal mastitis
non-lactational/pregnancy related mastitis
37
who gets periductal mastitis
smokers
38
Tx of periductal mastitis
augmenting 625mg orally every 8hrs for 7 days OR Cephalexin 500mg orally every 6-7hrs for 7 days
39
what is fat necrosis
damage + disruption of adipocytes due to injury to fatty breast parenchyma
40
presentation of fat necrosis
hard lump | - granulomatous response with subsequent fibrosis + calcification
41
what is mastalgia
breast pain
42
presentation of cyclical mastalgia
premenopausal women- average age 34 discomfort/fullness/heaviness can be unilateral/bilateral
43
presentation of non-cyclical mastalgia
older women - average age of 43 | continuous burning pain
44
Tx of mastalgia
good fitting bra topical NSAID primrose oil gamolenic acid/tamoxifen/bromocriptine if severe
45
what does bilateral milky discharge suggest
galactorrhea
46
drugs that can cause gynaecomastia
digoxin spironolactone anti-oestrogens