Microbiology Flashcards

(52 cards)

1
Q

what organisms make up the normal vaginal flora

A

lactobacillus
Strep viridian’s
Group B strep
Candida

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2
Q

why is lactobacillus important for the vaginal flora

A

produces lactic acid + hydrogen peroxide which suppresses the growth of other bacteria

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3
Q

what are the non-sexually transmitted genital tract infections

A

candida infection- vaginal thrush
bacterial vaginosis
prostatitis

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4
Q

predisposing factors for candida infection

A

recent antibiotic therapy
poorly controlled diabetes
High oestrogen levels ( e.g. pregnancy, certain types of contraceptive)
Immunocompromised patients

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5
Q

symptoms of candida infection

A

intensely itchy white vaginal discharge- cottage cheese discharge
spotty rash

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6
Q

diagnosis of candida infection

A

clinical diagnosis

High vaginal swab (HVS) for culture

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7
Q

1st line treatment for candida infection

A

topical clotrimazole 500mg (2-3 times daily)

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8
Q

2nd line treatment for candida infection

A

oral fluconazole 150mg + topical clotrimazole 500mg

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9
Q

what is the appearance of candida ablicans

A

yeast structure with budding

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10
Q

symptoms of bacterial vaginosis

A

thin, watery, fishy smelling discharge

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11
Q

investigation of bacterial vaginosis

A

clinical diagnosis
Raised vaginal pH (pH >4.5)
HVS

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12
Q

Treatment of bacterial vaginosis

A

metronidazole 500mg twice daily

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13
Q

classification of prostatitis

A
  1. acute
  2. chronic
  3. chronic prostatitis/chronic pelvic pain syndrome
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14
Q

symptoms of prostatitis

A

UTI symptoms- dysuria, increased frequency, nocturia, haematuria
Lower abdominal pain, back pain, penile pain
Tender prostate on examination

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15
Q

what organism causes bacterial prostatitis

A

E.Coli

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16
Q

if a patient has acute bacterial prostatitis, what else should you test for

A

STI if <35, gonorrhoea, chlamydia

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17
Q

investigation for acute bacterial prostatitis

A

Clinical signs

Mid-stream Urine sample (MSSU)

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18
Q

What type of urine sample is used to test for STI

A

First pass urine

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19
Q

1st line treatment for acute bacterial prostatitis

A

Ciprofloxacin for 28 days

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20
Q

2nd line treatment for acute bacterial prostatitis

A

Trimethoprim for 28 days if high C.Diff risk

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21
Q

commonest bacterial STI in the UK

22
Q

where can chlamydia affect

A

urethra, throat, rectum, eyes

23
Q

how does chlamydia stain with gram stain

A

NO stain, as there is no peptidoglycan in the cell wall

24
Q

which serovars of chlamydia cause lymphogranuloma venereum

25
What is lymphogranuloma venereum
inflammation of the rectum- can mimic crohn's | rectal pain, discharge + bleeding
26
treatment of chlamydia
Azithromycin 1g oral | Doxycycline 100mg bd 7 days for complicated case
27
how is chlamydia diagnosed
NAAT
28
How does neisseria gonorrhoea appear on gram staining
gram -ve diplococcus- like two kidney beans facing eachother
29
where does gonorrhoea affect
mucous membranes of urethra, endocervix, rectum + pharynx
30
male symptoms of gonorrhoea
purulent discharge | dysuria
31
1st line treatment of gonorrhoea
IM ceftriaxone 500mg
32
2nd line treatment of gonorrhoea
Cefixime 400mg oral
33
co-treatment of gonorrhoea + chlamydia
IM ceftriaxone + oral azithromycin
34
most common viral STI
Genital warts
35
what causes genital warts
HPV 6 + 11
36
Which type of HPV causes cancer
HPV 16 + 18
37
How are genital warts spread
close contact
38
treatment of genital warts
Cryotherapy Imiquimod cream Podophyllotoxin
39
appearance of genital warts
whiter than the surrounding skin with a rough surface
40
who gets a HPV vaccine
girls 11-13 men who have sex with men people with HIV Vaccinates against 6, 11, 16, 18
41
what causes genital herpes
HSV 1 | HSV 2
42
Which form of HSV causes recurrent genital herpes
HSV 2
43
which form of HSV causes cold sores
HSV 1
44
how are genital herpes spread
genital-genital contact | oropharyngeal-genital contact
45
presentation of genital herpes
painful multiple small vesicles that are easily deroofed
46
investigation for genital herpes
swab of deroofed blister for PCR
47
Treatment for genital herpes
Aciclovir pain relief topical lidocaine if very painful
48
What is trichomonas vaginalis
single celled protozoal parasite
49
symptoms of trichomonas vaginalis
vaginal discharge irritation urethritis in males
50
Investigation of trichomonas vaginalis
HVS (females) | Mid-stream urine sample (males)
51
treatment of trichomonas vaginalis
oral metronidazole
52
treatment for lice
mathalion lotion