Benign mesenchymal neoplasm 3 Flashcards Preview

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Flashcards in Benign mesenchymal neoplasm 3 Deck (36)
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1

where are Granular cell tumors fount intraorally?

Develop on any cutaneous or mucosal surface, but 40% occur on the tongue

2

CLINICAL characteristics of Granular Cell Tumors:

- Slow-growing, demarcated (though unencapsulated), non-tender submucosal nodule

- Most are less than one cm. in size

- Tongue is favorite site, but buccal mucosa and floor of mouth may be affected

3

Prognosis/treatment for Granular cell tumors:

Conservative excision is usually curative

Prognosis is excellent

4

___________ is a rare lesion of undetermined histogenesis, that appears on the maxillary ridge of newborns

Congenital Epulis

5

general characteristics of Congenital Epulis:

- Found at birth on the maxillary ridge of girl babies

- Smooth-surfaced, often pedunculated

- Vary in size

6

Histological characteristics of Congenital Epulis:

A) Microscopically shows a benign proliferation of cells having granular cytoplasms

B) No pseudoepitheliomatous hyperplasia

C) No S-100 positivity

7

What is the treatment protocol for Congenital Epulis?

- Conservative excision
- No tendency to recur
- Some reports of spontaneous involution without surgery

8

what is the most common tumor of childhood?

Hemangioma

9

what are the most common sites for hemangiomas?

Head and neck region is frequently affected

Tongue is most common intraoral site

10

clinical presentation of Hemangiomas:

A) Usually red in color, but can range through various shades of purple, depending on the caliber of vessels

B) Most are elevated, but macular lesions are also seen (“port wine stain”; nevus flammeus)

C) Variable in size

11

what diagnostic tool can be used to determine whether a red lesion (hemangioma) is due to extravasated blood or to blood that is contained within vessels

diascopy

12

T/F: Hemangiomas will "blanch" if pressed with a glass slide

True

13

What are the treatment options for hemangiomas?

1) Surgical excision, cryotherapy, embolization or use of sclerosing agents if cosmetically unacceptable

2) If lesion impairs vision, treat as soon as possible

3) Otherwise, wait until child is at least 6 years of age

14

_________________ is also known as Sturge-Weber syndrome (really should be “anomalad”)

Encephalotrigeminal Angiomatosis

15

T/F: Encephalotrigeminal Angiomatosis is a congenital abnormality, not an inherited or genetic problem

True

16

what is the definition of Encephalotrigeminal Angiomatosis?

Hemangiomatous process affecting superficial and deeper tissues in region of cranial nerve V

17

Clinical symptoms of Encephalotrigeminal Angiomatosis:

1) Patients exhibit nevus flammeus in distribution of 1st, and sometimes 2nd or 3rd, division of C.N. V

2) Involvement of deeper soft tissues as well as meninges of brain

3) Seizure disorders, mental retardation, and hemiplegia may be present

18

Radiographic signs of Encephalotrigeminal Angiomatosis:

A) Classic radiographic finding of “tram-line” calcifications seen on skull film

B) Parallel calcifications probably represent the calcified walls of abnormal blood vessels

19

_________ is a benign neoplasm of lymphatic vessel differentiation

Lymphangioma

20

Clinical characteristics of Lymphangiomas:

1) Often present at birth
2) Tongue is most common intraoral site
3) Surface has a vesicular appearance, similar to “frog eggs” or “tapioca pudding”

21

Cystic Hygroma are simply a large form of what condition?

lymphangioma

22

what areas of the body can be effected by Cystic Hygroma? why is this especially concerning?

1) May affect the neck, mediastinum, axilla and the oral cavity

2) Important because this lesion may cause airway obstruction, particularly if it becomes secondarily infected

23

Treatment protocol for Cystic Hygromas:

- Management depends on size of lesion
- More difficult to treat than hemangioma because it is often difficult to discern the borders of the tumor
- Surgical excision is the treatment of choice
- Relatively high recurrence rate: up to 40% in some series

24

____________ is a benign tumor of smooth muscle differentiation

Leiomyoma

25

clinical characteristics of Leiomyomas:

1) Most in the oral region probably arise from vascular smooth muscle

2) Well-demarcated, rubbery firm, less than 1 cm in diameter

3) May have a reddish or purplish color due to their vascular nature

26

where are Leiomyomas usually found?

Most common in the upper lip, buccal mucosa and palate

27

Histological features of Leiomyomas:

1) Benign proliferation of cells that resemble smooth muscle
2) Spindle-shaped, with cigar-shaped nuclei and eosinophilic cytoplasms
3) No significant atypia, and no mitotic activity
4) Positive for markers of muscle differentiation

28

Treatment options for Leiomyomas:

Treatment consists of conservative excision
Prognosis is excellent
Virtually no chance of recurrence

29

____________ are very rare, benign tumor of skeletal muscle differentiation

Rhabdomyoma

30

T/F: Most rhabdomyomas arise in the heart (“cardiac rhabdomyoma”)

True