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Flashcards in benign mesenchymal neoplasms 1 & 2 Deck (45)
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a __________ is a Collagen deposition secondary to chronic trauma



where are fibromas usually found? what are their clinical/histological characteristics?

A) found on Buccal mucosa, tongue

B) Smooth-surfaced, dome-shaped nodule clinically

C) Dense fibrous connective tissue histopathologically


what is the most common treatment for Fibromas?

Conservative excision


"Inflammatory Fibrous Hyperplasia" is also known by what other names?

Also known as denture epulis, epulis fissuratum, or denture-induced fibrous hyperplasia


what is the major cause of Inflammatory fibrous dysplasia? what are the clinical characteristics? what treatments are available?

A) Cause = Flange of ill-fitting denture

B) clinically, they may have central fissure

C) Conservative excision; re-make denture


characteristics of Denture papillomatosis:

A) form of Inflammatory Fibrous Dysplasia
B) happens on maxillary complete denture
C) effects central region of hard palatal mucosa
D) Numerous asymptomatic RED PAPULES


what are the clinical characteristics of Pyogenic Granuloma? where can they be found?

- Rapidly growing, painless, reddish mass
- Any body surface; bleeds easily
- Gingiva, lips, tongue commonly effected
- Frequently occurs during pregnancy


what are the histological characteristics of Pyogenic Granulomas? what is the treatment protocol for them

Microscopically: granulation tissue

Excise, remove irritants; 15% recur


what are the clinical & histological findings for Peripheral giant cell granulomas?

A) Painless mass with a dusky-purple hue

B) Microscopically: granulation tissue with numerous benign multinucleated giant cells


where are Peripheral Giant Cell Granulomas found?

Found ONLY on the gingivae and alveolar process


what is the treatment protocol for peripheral giant cell granulomas?

Excise, remove irritants; 15% recur


_______________ are painless, firm, coral-colored masses found on the gingiva

Peripheral Ossifying Fibroma


what is the microscopic structure of a Peripheral Ossifying Fibroma?

cellular fibrous connective tissue with variable amounts of calcification


T/F: the treatment for Peripheral Ossifying Fibromas is the exact same as the treatment for Peripheral Giant cell Granuloma


Excise, remove irritants; 15% recur


what is the definition of a "Lipoma"?

Benign tumor of adipose tissue


what group is at risk for Lipomas? what are the clinical characteristics?

A) Adult patients
B) Slow-growing, non-tender, soft, doughy, usually encapsulated
C) Common in head and neck; occasionally found intraorally
D) Yellow if close to the surface


what are the histopathological finding for Lipomas?

Demarcated or encapsulated collection of mature fat cells


Treatment protocol for Lipomas:

- Enucleation or conservative surgical excision
- Virtually no tendency to recur
- No evidence of malignant transformation


_______________ Represents an uncommon reaction to the sectioning of a nerve

Traumatic Neuroma


Clinical characteristics of Traumatic Neuromas:

- Smooth-surfaced, dome-shaped papule, usually less than one cm.

- Tongue, buccal vestibule are often affected

- May be tender on palpation


what are the histological characteristics of Traumatic neuromas?

- Microscopically, a tangled mass of peripheral nerve fibers is seen

- Usually set in a collagenous background


a ____________ is a benign tumor of schwann cell origin

Neurilomoma (Schwannoma)


clinical characteristics of Neurilomomas

A) Most are identified in adults
B) Slow-growing, solitary, encapsulated, rubbery-firm, non-tender mass
C) Lips, tongue, buccal mucosa
D) May be seen within the mandible


General histological characteristics of Neurilomomas:

Well-developed connective tissue capsule

Benign proliferation of spindle-shaped schwann cells

Presene of Antoni Patterns (A & B)


what types of "Antoni patterns" are seen in Neurilomomas? Describe each

A) Antoni A and Antoni B patterns are seen

B) Antoni A featuring palisaded nuclei arranged around acellular hyaline material (Verocay bodies)

C) Antoni B more disorganized, myxoid


what are the treatment options for a Neurilemoma?

- Treatment consists of conservative excision

- Lesion usually “shells out” due to dense connective tissue capsule

- Virtually no tendency to recur

- Extremely rare malignant transformation


what lesion is defined as a "Benign tumor of neural fibroblast origin"



what are the clinical characteristics of Neurofibromas?

A) Over 90% are solitary; most of remainder are multiple and associated with neurofibromatosis

B) Soft, dome-shaped, non-tender, superficial nodule affecting skin or mucosa

C) Demarcated, but unencapsulated


T/F: in Neurofibroma lesions, lesional tissue tends to mingle with the adjacent normal tissue



Treatment/prognosis/reoccurance of Neurofibromas:

A) Treatment consists of simple, conservative excision

B) Prognosis is generally good

C) Uncommon possibility of malignant transformation to malignant peripheral nerve sheath tumor; especially rare for small, superficial lesions