Benign vaginal and vulval conditions Flashcards

(46 cards)

1
Q

Define lichen simplex chronicus.

A

An itch scratch cycle typically leads to chronic trauma from rubbing and scratches.

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2
Q

What are the clinical features of lichen sclerosus?

A
  • Asymptomatic
  • Anogenital pruritus that worsens at night
  • Excoriations and thickening of vulvar skin
  • Dyspaurenia
  • White atrophic papules
  • Distortion of vulvar anatomy: Labia minora regression, Clitoral concealment, Urethral obstruction, Introital stenosis
  • Crinkling of the skin
  • Formation of figure 8 due to involvement of perineum and anus
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2
Q

How is lichen simplex chronicus diagnosed?

A

Clinical

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2
Q

How is lichen simplex chronicus treated?

A

Treatment
Ellimination of provocative stimuli
Topical corticosteroid ointments
Lubricants: plain petrolatum, vegetable oil, cool sitz

To reduce scratching
Oral antihistamines
Trim finger nails
Cotton gloves worn at night

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2
Q

What are the clinical features of lichen simplex chronicus?

A
  • Intense pruritus
  • Excoriations within a background of erythema
  • Lichenification
  • Thickness of vulvar skin with exaggerated skin markings causing a leathery, gray appearance
  • Functional and psychological distress
  • Disruption of sleep
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2
Q

In which women is lichen sclerosus common?

A

Post-menopausal

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2
Q

What causes pruritis in lichen simplex chronicus?

A
  • Irritation from clothing, heat or sweating
  • Chemicals (hygiene products, topical medications, laundry product
  • Food sensitivities
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2
Q

How is lichen planus treated?

A

Pharmacotherapy
Ultra potent topical corticosteroid ointments
Systemic corticosteroids
Topical tacrolimus ointment
Oral retinoids

Vaginal dilators

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2
Q

Give 2 suggested causes of lichen sclerosus.

A

Infections, hormonal, genetic and autoimmune

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3
Q

How is lichen sclerosus diagnosed?

A

Clinical and histology

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3
Q

Give 5 clinical features of lichen planus.

A
  • Pruritus
  • Superficial dyspaurenia
  • Post coital bleeding
  • Nail bed involvement: longitudinal ridging and sandpaper effect
  • Genital lesions: Longitudinal, annular, ulcerative, hyperpigmented and bullous
  • Mouth lesions: Reticular like cobwebs
  • Skin lesions
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3
Q

What kind of condition is lichen planus?

A

Autoimmune

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3
Q

How is lichen sclerosus treated?

A
  • Corticosteroids
  • Oral antihistamines
  • 2% lidocaine jelly
  • Estrogen cream: indicated for menopausal atrophy, labial fusion and dyspaurenia
  • Retinoids: severe non responsive cases of lichen sclerosus, or patients with intolerance for corticosteroids
  • Topical calcineurin inhibitors (tacrolimus)
  • Phototherapy
  • Surgery
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3
Q

What the 3 forms that lichen planus can present in?

A

Erosive

Papulo-squamous

Hypertrophic

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3
Q

How do you differentiate irritant and allergic contact dermatitis?

A

Irritant- Immediate burning and stinging upon exposure to an offending agent

Allergic- Delayed onset and an intermittent course of pruritus and localized erythema, edema and vesicles/ bullae

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4
Q

How is contact dermatitis treated?

A
  • Elimination of offending agent
  • Restoration of the natural protective skin barrier
  • Topical corticosteroids
  • Scratch cessation
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5
Q

How does intertrigo come about?

A

Due to friction between moist skin surfaces

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6
Q

Give 5 clinical features of intertrigo.

A
  • Erythema
  • Erosions
  • Fissuring
  • Pruritus
  • Hyperpigmentation
  • Crusting
  • Maceration
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7
Q

How is intertrigo treated?

A

Drying agents such as corn starch

Mild topical corticosteroids

Use of antibiotics if superinfected

Lightweight loose fitting clothing made of natural fibers

Improved ventilation

Thorough drying between skin folds after bathing

8
Q

Define hidradenitis suppurativa.

A

Recurrent papular lesions that may lead to abscess, fistula formation, and scarring predominantly in apocrine gland bearing skin.

9
Q

How is hidradenitis suppurativa treated?

A
  • Local hygiene and weight reduction in obese patients
  • Topical or oral antibiotics
  • Warm compresses
  • Non medical therapies: laser and phototherapy
  • Surgical excision
10
Q

What are apthous ulcers?

A

Self limited mucosal painful ulcers

11
Q

What are potential triggers of apthous ulcers?

A

Stress, trauma, infection, hormonal fluctuation, and nutritional deficiencies of vitamin B12, folate, iron or zinc

12
Q

How are apthous ulcers treated?

A
  • High potency corticosteroids
  • Colchine
  • Dapsone
  • Thalidomide
13
Define psoriasis.
T cell mediated autoimmune process in which pro inflammatory cytokines induce keratinocyte and endothelial cell proliferation.
14
How does psoriasis present?
Thick red plaques covered with silvery scales, pruritis minimal or absent
15
How is psoriasis treated?
- Topical corticosteroids - Vitamin D analogues - Phototherapy
16
What is atopic dermatitis?
Severe pruritic dermatitis that follows a chronic, relapsing course
17
How is atopic dermatitis treated?
Topical corticosteroids and immunomodulators such as tacrolimus Skin moisturizing with emollients
18
What is acanthosis nigricans characterized by?
Velvety to warty, brown to black, poorly marginated plaques
19
What is acanthosis nigricans associated with?
Insulin resistance with compensatory hyperinsulinemia
20
How is acanthosis nigricans treated?
No proper treatment. Weight loss can ameliorate insulin resistance. Compliance to DM medication. Topical keratinolytics and exfoliants may have benefit.
21
What does crohn's disease present with?
- Asymmetrical vulvar edema - Ulceration (linear “knife-cut” which affect inguinal, genitocrural, and interlabial folds) - Hypertrophic lesions - Chronic abscesses
22
How is crohn's disease treated?
- Treat underlying GI crohn disease - Topical or intralesional corticosteroids - Anti tumor necrosis factor alpha treatments - Surgery
23
What is Behcet's disease?
Rare, chronic, autoinflammatory, systemic vasculitis
24
What are the 3 classifications of nevi?
Junctional: located at epidermis-dermis junction Compound: evolve over time to reside entirely within the dermis Dermal: extend into dermis
25
What is vitiligo?
Loss of epidermal melanocytes leading to depigmentation which progresses over time
26
How is vitiligo treated?
- Narrowband ultraviolet B phototherapy - Excimer laser therapy - Topical immunomodulators
27
Name 2 epidermal and dermal lesions.
Acrochordons, Seborrheic keratosis, Keratoacanthoma, Syringoma
28
Name 2 subcutaneous masses.
Leiomyoma, Fibroma, Lipoma
29
Name 2 cystic vulvar tumors.
Bartholin gland duct cyst and abscess, urethral diverticulum, epidermoid cyst
30
What is vulvovaginitis?
Inflammation of the vulva and vagina
30
Give 2 infectious and 1 non-infectious cause of vulvovaginitis.
Infectious Bacterial vaginosis, fungal(candida), protozoal(Trichomoniasis) Others: Gonorrhea, chlamydia Non infectious Atrophic vaginitis
30
What causes external genital warts?
Human papillomavirus (HPV) 6 or 11
31
What is the classic sign for external genital warts?
Cauliflower like growths
32
How are external genital warts treated?
- Cryotherapy - Trichloroacetic acid - Surgical excision