Bio 2nd Exam Flashcards

(142 cards)

1
Q

What is Hydrolysis?

A

○ Decomp. By insertion of water molecules between certain bonds of the macromolecules

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2
Q

What is Ingestion

A

Occurs when we take food through our mouth

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3
Q

What is Digestion

A

○ Breakdown of larger pieces of food into smaller pieces
○ Can be mechanical or chemical

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4
Q

What is Mechanical Digestion?

A

Primarily by chewing in mouth and by wavelike contractions of the smooth muscles in the stomach

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5
Q

What is Chemical Digestion?

A

Digestive enzymes all have pH ranges at which most effective
Compartmentalization of the digestive tract helps establish these ideal pH ranges.

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6
Q

What is Peristalsis?

A

Wavelike contractions that propel substances along a tubular structure such as the esophagus

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7
Q

What is a Lumen?

A

Cavity inside any tubular structure, such as the lumen of the digestive tract

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8
Q

What is Mucosa

A

Membrane that lines tubes and body cavities that open to the outside of the body; also called mucous membrane.

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9
Q

What is Diverticulosis

A

A condition in which portions of the digestive tract mucosa have pushed through other layers of the tract, forming pouches where food may collect.

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10
Q

What are the two types of Digestion?

A

Intracellular
Extracellular

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11
Q

Examples of Intracellular Digestion

A

Amoeba
White blood cells

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12
Q

How does intracellular digestion work along with end product?

A

Process is endocytosis
§ End product is food vacuole

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13
Q

Examples of Extracellular Digestion

A

Homo sapiens

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14
Q

How does Extracellular Digestion work?

A

Requires both a digestive and circulatory system (much more complex)

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15
Q

Less Complex organisms

A

○ Protozoans
○ Flatworms
○ Sea Anemones
○ Roundworms
Earthworms

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16
Q

What is the Oral Region?

A

Site of ingestion

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17
Q

What are the parts of the Oral Region?

A

Mouth, Teeth and tongue

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18
Q

Smaller parts of the Oral Region?

A

○ Salivary Glands
§ Secret Salvia
§ Contains Salivary Amylase
□ First enzyme
○ Teeth
§ Mostly cosmetic today
○ Tongue
Taste buds

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19
Q

Esophagus

A

Peristalsis

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20
Q

Parts of the Stomach

A

Gastroesophageal sphincter
Duodenum

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21
Q
  1. Functions of Stomach
A
  1. Parietal cells -> Secrete -> HCl (pH of 1 -> 2)
    ○ Functions of Hydrochloric Acid
    § Kills bacteria
    § Denatures protein (Alters both the structure and physical properties)
    Activates Pepsin
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22
Q
  1. Functions of Stomach
A
  1. Chief cells -> secrete -> Pepsinogen -> (in HCl) -> Pepsin (hydrolyses Protein)
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23
Q
  1. Functions of Stomach
A
  1. Epithelial Cells -> Secrete -> Mucus
    i. Provides protection of stomach cells from digestion (life span of only a few days)
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24
Q

Additional Functions of Stomach

A

○ Absorption of:
§ Alcohol
§ Some prescription Drugs

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25
First two secretions of the Pancreas and what they do
§ Sodium Bicarbonate (NaHCO3) □ Changes pH of chyme from Acid to Base (alkaline) § Lipase □ Hydrolyses fats (lipids) to: Glycerol & fatty acids
26
Last 3 secretions of the Pancreas and what they do
§ Proteases □ (old names Trypsin & Chymotrypsin) □ Digestion of Proteins to: Amino Acids § Carbohydrases □ Change complex sugars to simple sugars (under the influence of Insulin from the Pancreas) □ Diabetes: Type A, Type B § Nucleases □ Hydrolyze RNA & DNA to Nucleotides & Nitrogenous bases
27
Liver
○ Gallbladder secretes Bile ○ Bile § Serves to emulsify Fats (lipids) Stores glucose as glycogen
28
Small intestine
○ Duodenum § First 8-10 in ○ Length of approximately 18ft ○ Surface area of almost 200 square meters ○ Final Digestion and absorption of the food stuffs
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Large Intestine
○ Re-absorption of water ○ Storage of waste material until defecation
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Anorexia Nervosa
§ Self-imposed starvation
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Bulimia Nervosa
§ Overeating followed by self-induced vomiting
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Muscle Dysmorphia
Preoccupation with underdeveloped body
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Peptic Ulcers
○ Both genetic and life style influenced § Helicobacter pylori are bacteria that can cause an infection in the stomach. Reason for: Colon Cancer, Diarrhea, Dysentery
34
Colon Cancer
Prevention with high fiber diet Broccoli, salads, whole grains etc.
35
Diarrhea
Traveler's diarrhea or Montezuma's revenge
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Dysentery
Amoebic dysentery - protozoan infection (spread by houseflies)
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Two noteworthy problems about milk
§ High butterfat content □ Triglycerides found in milk § Lactose intolerance □ Primary sugar in milk □ One cannot digest dairy products
38
Soy Milk
□ Contains about the same proportion of protein as cow's milk □ Is there an advantage to drinking soy milk? ® Yes ® More healthy than animal fats
39
Cellular Respiration
* Process by which the chemical energy stored in food (glucose) is converted into usable energy * ADP -> "ATP" (in Mitochondria) ATP -> ADP + Energy (in Muscle Tissue)
40
Normal Cellular respiration
○ Takes place in Mitochondrion ○ Uses Oxygen ○ Produces 36 ATP's from the glucose molecule 38% efficient
41
ATP
○ Stored chemical energy (glucose) Is converted to mechanical work (by muscles) ○ Different pathways of pyruvic Acid § Ethyl Alcohol Latic Acid
42
Latic Acid Fermentation
○ Occurs in overworked muscle tissue ○ Pyruvic acid (3 carbons) -> Lactic Acid (3 carbons) + energy ○ Produces an Oxygen debt that must be repaid later Only 7% efficient
43
Alcohol Fermentation
○ Occurs in yeast cells ○ 13% efficient Pyruvic Acid (3 carbons) -> ethanol (C2H5OH) + CO2
44
Aerobic respiration
Cellular respiration in cells
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Anaerobic Respiration
Bacteria such as tetanus, gas gangrene & botulism
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Human Heart
○ Weights 250-350 gms ○ 72 beats/minute 2.5 billion times/lifetime
47
Function of Circulatory system
○ Delivers nutrients and O2 to individual cells ○ Remove the by-products of digestion and cellular respiration from individual cells: § Nitrogenous waste -> Kidneys § CO2-> lungs ○ Temperature Regulation ○ Transports hormones from the site of production to their respective target cells § Testosterone - from the testes § Estrogen - from the ovaries § Growth Hormone - from the Pituitary Gland ○ Penis erection in some mammals such as H. sapiens
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Lymphatic System
○ Organ system consisting of lymphatic vessels and lymphatic organs that transport lymph and lipids; aids the immune system
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Two types of Circulatory systems
Closed and open system
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Closed system
§ Blood is contained within the vessels § Ex. Vertebrates - including H. sapiens § Heart -> Artery -> Capillaries -> Vein -> Heart
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Open System
§ Blood comes in direct contact with the cells § Ex. Grass hopper Heart -> Artery -> Blood Cavity -> Vein -> Heart
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Chambered hearts examples
○ Fish- two chambered heart ○ Amphibian - three chambered heart ○ Reptile - modified three chambered heart ○ Birds & Mammals - four chambered heart
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Systems of the Heart
Coronary system Pulmonary System Systemic System
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Coronary System
§ Heart and its blood supply (coronary artery)
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Pulmonary system
§ Includes: □ Pulmonary artery □ Lungs □Pulmonary vein
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Systemic System
§ Aorta § Capillaries § Vena Cava □ (superior & inferior)
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Four Chambered heart
○ Two Atria § Thin walled ○ Two Ventricles § Thich walled ○ Two valves in between § Tricuspid valve § Bicuspid valve (AKA mitral valve)
58
Heart murmur
Caused by several childhood diseases
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IMPORTANT NODES
Sinoatrial node (pacemaker) Atrioventricular node
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Systole
Contracted phase of the heart
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Arteries
○ Red vessels =↑ in oxygen Blue vessels =↑ in Carbon dioxide
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Blue Baby
○ Cyanosis Fetal heart basically by-passes the pulmonary circuit until partition (birth)
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Blood flow
○ Heart -> Artery -> Capillaries -> Vein -> Heart
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Arteries
carry blood away from the heart § Elastic - absorb pressure from the heart Lack valves ○ These may harden with age - causing ↑ in blood pressure § Hypertension □ Affected by diet among other factors
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Capillaries
Width of the red blood cells and serve the individual cells
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Veins
§ Carry blood back to the heart Contain valves
67
Angioplasty
Balloon in clogged arteries
68
Stent
§ a perforated tube is placed in the artery § Meth?
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Bypass Surgery
replace damaged arteries w/veins from the patient's own legs
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Transplants
Difficult to find suitable donor and problems with the patient's own immune system.
71
Baboon heart
Case of "Baby Jane/Fae" in California 1980s
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Artificial heart
Problem with damage to the patient's own blood cells
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Blood
○ Average person has ≈ 5 liters (≈ 5 quarts) ○ ≈ 55% is Plasma (which is 90% water) ○ Rest is mostly plasma proteins
74
Albumin
Homeostasis & water recovery
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Globulins
Contribute to immune system
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Fibrinogen
Functions in blood clotting
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Clotting Mechanism
○ Damaged cells -> release -> thromboplastin ○ Prothrombin -> Activates -> Thrombin Fibrinogen -> activates -> fibrin threads
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Erythrocytes
○ Red blood cells ○ RBC's ○ Life span ≈ 4 months Produced by the marrow of the long bones
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Hemoglobin
§ Iron (Fe) Absorbs 99 times the Oxygen as plasma
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Problems with Erythrocytes
○ Leukemia ○ Radiation Sickness Bone marrow transplants
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Why is there a differences between life expectancy of males and females?
§ Varying levels of Iron (Fe) in the blood of males and females
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Sources of Iron in our diet
○ Red Meat ○ Some organs § Liver ○ Anemia
83
Hadacol
○ Vitamins B1, B2, Iron and Niacin ○ 12 percent alcohol ○ Press release in 1951 AMA 66 times the dose of modern iron supplements
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Leucocytes
○ White blood Cells (WBC) ○ Less than 0.1% of blood ○ Also produced by the bone marrow Provide a defense against foreign invaders of the blood exhibit amoeba-like feeding - "Phagocytosis" - endocytosis
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Rx of two different diseases/infections
○ Sexual transmitted Disease (STD) § Gonorrhea ○ Rx is an injection of an Antibiotic ○ Bitten by a rabid dog, skunk, bat, etc. Rx is a vaccination
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How were antibiotics first produced?
○ First produced by Fungi § Compete naturally with bacteria Directly attack antigent
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Some examples of fungi?
○ Terramycin § Earth mold ○ Penicillin Isolated from the mold Penicillium
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Antibiotic Resistance
Due to overuse & misuse some bacterial strains have become resistant
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Methicillin-resistant Staphylococcus aureus
§ Superbug Does not respond to Rx with many antibiotics
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Vietnam War
○ 46 deaths ○ Emergence of chloroquine-resistant P.Vivax Quinine
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Leprosy
○ Bacterial infection Carried by armadillos
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Axillary Lymph nodes (Lymphatic System)
Located in the underarm region
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Red bone marrow (Lymphatic System)
Site for the origin of all types of blood cells
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Thymus
Lymphatic tissue where T lymphocytes mature and learn to tell "self" from "nonself"
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Network of fluid-carrying vessels & associated organs flow of lymph is on-way
Lymphatic system Vessels have valves - but no pump
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Lymphocytes
Defense against pathogens
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Types of lymphocytes
B lymphocytes T lymphocytes Both function in the production of Antibodies which will attack foreign proteins known as Antigens
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B lymphocytes
§ B-cells § First found in Bursa (joints) of chickens § Formation in H. Sapiens is not entirely understood but they mature in the bone marrow
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T lymphocytes
T- cells produced by the Thymus gland (chest) and in bone marrow
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Similar of Lymphatic and Circulatory Systems
§ It has valves □ Similar to both the heart and the veins § Produces cells □ Lymphocytes instead of RBC's and WBC's
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Differences of Lymphatic and Circulatory Systems
§ Open system § Does not have a pump § Does not have capillaries It does not function in the exchange of Oxygen and Carbon Dioxide
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Classic example of diseases
Smallpox and Cowpox in Europe during the 1700's
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Primary immune response
Often very slow - may take days, weeks or longer for Antibody levels to become high enough
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Secondary immune response
Occurs very quickly & provides immediate protection
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Well known Viral infections
○ HIV- Human immunodeficiency Virus ○ AIDS- Acquired Immunodeficiency Syndrome § In 2005 - AIDS killed an estimated 2.4 to 3.3 million lives § One does not die directly of AIDS - but instead one dies of some other infection ○ Influenza ○ Swine flue ○ H1N1 ○ West Nile & Zika viruses § Carried by mosquitoes (vector) ○ Polio (poliomyelitis) Monkeypox
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Categories of Risk
○ High Risk § Poorly developed when young § Common in the elderly ○ Low Risk § Best developed when mature ○ System will begin to fail with time and/or age often requires a "booster" § Tetanus shot Annual flu shot
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Polio Vaccine
§ Salk Vaccine (injected) in early 1950s § Sabin Vaccine (oral) in late 1850s § Completely eradicated in the Americas by 1994 350,000 cases in 1988 - down to 1,652 in 2007
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Flu Pandemic
§ Estimates of 50-100 million deaths worldwide § In the US Estimates of 500,000 - 675, 000 deaths
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Ebola
§ Spread by exchange of body fluids § Epidemic in SW Africa □ (Guinea, Liberia & Sierra Leone) § Recent death in Dallas - Spring 2014 § Mr. Duncan had shutdown of organ systems Two nurses also diagnosed with Ebola
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Enterovirus (EV-D68)
§ Colorado School Children fall of 2014 § Ages 1-18 § Polio-like virus May have been introduced by immigrants from El Salvador, Honduras & Nicaragua
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Zika
§ Microcephaly in unborn children Summer & fall of 2016
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Coronavirus disease 2019 (Covid-19)
§ When viewed under a microscope, Covid had a crown-like structure.
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Short History of Recent vaccines
○ Modified or quick-kill process ○ Rendered the live virus ineffective ○ The immune system to produce own antibodies Early polio vaccines was not completely deactivated giving polio to children
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Types of vaccines
○ MLV's § Killed Vaccines ○ Live-attenuated vaccines § Get rid of parts Inactivated vaccines
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COVID Vaccine
○ None of the nucleic acids of original virus are used Use mRNA (messenger RNA) to induce body to produce its own antibodies in place of the original virus template
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Advantages of COVID Vaccine
§ Don't use the original viral template Allows researchers to "re-program" the mRNA sequence to respond to any new variant such as "Delta variant"
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New variants of COVID
Mutation that originates and thrives in a region with little or no medical facilities
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Other medications used for COVID Rx
○ Remdesivir § Broad-spectrum antiviral medication ○ Hydroxychloroquine § Malaria Rx ○ Ivermectin § Anti-parasite for horses ○ Merck § Experimental pill for people sick with COVID19 A pill taken at home
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Childhood immunizations
○ DPT Vaccine (or some variant) Diphtheria - Pertussis (whooping cough) - Tetanus (Lockjaw)
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Tetanus
§ Causative agent □ Anaerobic bacteria □ 40-50 cases/year reported in US Worldwide - 500,00 to million/year mostly in new born children
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Excretion
Elimination of metabolic waste arising from the digestion of proteins
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Digestion of protiens
○ Known as Deamination Ammonia converted to Urea and flushed from body by a process known as urination
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Urine
○ Produced in Kidney -> Ureter -> Bladder -> Urethra ○ Kidney stones & STD's
125
Nephron
§ Basic unit of the kidney Blood pressure of 70 mm/Hg (most capillaries have only 30 mm/Hg)
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Loop of the Nephron
§ Functions in water recovery Very long in some desert mammals such as kangaroo rats
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Hemodialysis
§ More commonly known as Dialysis § Rx for renal failure □ Uses semi-permeable membrane § 3 to 5 hours required - 2 to 3 times a week § 240 Americans on dialysis die every day § Wait can be as long as 5- 10 years.
128
Kidney transplants
○ Most common organ transplanted ○ One year survival rates ○ 97% if from close relative ○ 90% if from a non-relative ○ Like heart transplants rejection is a problem ○ ~25,000/year in the US ○ Research underway for using kidney transplants from pig
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Xenotransplantation
Use of animal organs instead of human organs in human transplant patients
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Enlarged Prostate
○ BPH § Benigin Prostatic Hyperplasia ○ Prostate Cancer 2nd most common Cancer in men ○ Not a killer 98% survival rate Lung Cancer is most common and #1 killer
131
Respiration
○ Gaseous exchange of an organism with its environment ○ Primary concern is with O2 and CO2 ○ Not to be confused with Breathing
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Lower Respiration Tract
Trachea Bronchus Bronchioles Lung Alveoli Diaphragm
133
Trachea
passage of air to bronchi
134
Bronchus
Passage of air to lungs
135
Bronchioles
Passage of air to alveoli
136
Lung
Gas exchange
137
Alveoli
§ Smaller air sacs Site of gas exchange
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Diaphragm
§ Responsible for inhaling and exhaling Vagus nerve
139
Lungs (Breathing)
○ Normal Exchange - ~ 500cc ○ Maximum exchange - ~1200cc ○ Having the wind knocked out of you ○ Coming up from a SCUBA dive ○ Hiccoughs ○ Chest Puncture Wounds
140
Smoking
○ Emphysema & Lung Cancer ○ Secondary smoke ○ Asbestos workers ○ 480,000 deaths/year
141
Smoking while pregnant
§ Increase in miscarriages and stillbirths § Decrease in weight of the infant § Infant will be twice as susceptible to respiratory infections
142