bio final Flashcards

(28 cards)

1
Q

Structure of tough layers of transparent crystallin proteins that focuses light onto the retina
-Flexibility deteriorates with age

A

lens

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2
Q

Smooth muscles that stretch the lens to focus light.
-Produce Aqueous Humor
Ciliary
body

A

ciliary body

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3
Q

What are the 2 “humors” in the eye & where are they located?

A

Aqueous Humor: Fluid in the compartment in front of the lens that helps bend light and maintain
pressure.
Vitreous humor: Fluid filling the posterior compartment of the eye that also helps bend light and
maintain pressure.

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4
Q

Which tissues are affected by cataracts & glaucoma?

A

lens and muscle tissue

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5
Q

What is the difference between Myopia, Hyperopia, Astigmatism, and how is each corrected?

A

Myopia (Nearsightedness): Distant objects focus in front of retina, because the eye is longer than normal, cornea is too curved, or excessive amount of near-vision work.
-May be corrected with concave lenses (surface that curves inward)
Hyperopia (Farsightedness): The focal point of light from near objects is behind the retina because the eye is shorter than normal or the cornea has too little curvature.
Astigmatism: Irregularities exist in cornea or lens (ground lens)

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6
Q

What layer of the eye contains the blood vessels and pigment cells?

A

Choroid

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7
Q

What do the different photoreceptors detect?

A

Photoreceptors: The light detecting or “photosensitive” cells.
Rods: Cells very sensitive to light (allows vision in dim light).
Cones: Cells sensitive to color

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8
Q

What cells are involved in AMD and what happens to them?

A

AMD: Retina detaches and photoreceptors in the macula
degenerate, or vessels grow under the retina
Bipolar cells: Transmit action potential from photoreceptors to ganglion cells.
Ganglion cells: Neurons that form the innermost layer of the retina.

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9
Q

How do you say λ and what does it represent in waves?

A

λ( lambda) = wavelength

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10
Q

What are the 3 color opsins in humans?

A

blue green red

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10
Q

What wavelengths do insects see that we cannot?

A

Insect opsins can detect Ultraviolet wavelengths

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11
Q

Complex that detects dim light & consists of a transmembrane protein called Rod opsin and a
pigment retinal molecule

A

rhodopsin

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11
Q

Pigment molecule that detects light; acts like a light switch inside an opsin molecule.

A

11- cis retinal

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12
Q

Contain the photoreceptor discs.

A

Outer Segments of rods & cones.

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13
Q

Membrane-bound organelles in photoreceptors that contain light sensitive pigments

A

Photoreceptor discs

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14
Q

Precursor molecule of 11-cis retinal.
-Vitamin A deficiency can lead to night blindness and eventually blindness from hemorrhaging.

15
Q

Are photoreceptors depolarized or hyperpolarized in the dark?

16
Q

order of light stimulation

A
  1. Light stimulation of rhodopsin allows GTP to bind its attached G protein (Transducin).
  2. G proteins (transducins) activate cGMP PDE (phosphodiesterase).
  3. PDE breaks down hundreds of cGMP, reducing its concentration and closing cGMP-gated Na+/Ca2+
    4.Ion channels close in response to hyperpolarization.
  4. The cell stops releasing glutamate. (Retinal Bipolar cells have a receptor that activates when glutamate is NOT present)
17
Q

What are 4 muscle tissue functions?

A
  1. Many muscles resist movement
  2. Maintenance of posture
  3. Maintenance of blood pressure
  4. All muscles generate hea
18
Q

What are the Sarcolemma, T-tubule, and Sarcoplasmic Reticulum?

A

Sarcolemma: Specialized muscle cell membrane.
T-tubule: Invaginations of the cell membrane in cardiac & skeletal muscle.
Sarcoplasmic Reticulum (SR): Specialized muscle cell Endoplasmic Reticulum.

19
Q

What is the contractile unit of a Skeletal & Cardiac muscle?

A

sarcomere : which is The contractile unit of a Skeletal &
cardiac myofibril extending from one Z line to the
next

20
Q

What are the 2 contractile proteins?

A

Myosin: Protein that forms thick filaments in muscle.
Actin: Protein that forms thin filaments in muscle.

21
Q

Explain the steps of Muscle contraction using the diagram

A
  1. A motor neuron releases the neurotransmitter acetylcholine at the neuromuscular junction (NMJ).
  2. Acetylcholine binds receptor proteins on muscle that open Na+ channels.
  3. Action potential: Na+ rushes into the muscle cell depolarizing the membrane which opens a cascade
    of ion channels along the muscle membrane.
  4. Action potential passes into membrane
    extensions called T-tubules (transverse tubules).
  5. Impulse reaches the Sarcoplasmic reticulum
    which opens calcium (Ca2+) channels.
  6. Ca2+ binds Troponin, which moves Tropomyosin,
    opening myosin binding sites on actin.
    Troponin and Tropomyosin: Two inhibitor
    proteins that surround actin filaments
    preventing myosin from interacting.
  7. Myosin heads bind actin to form cross-bridges.
    -This shortens the sarcomere (i.e. muscle
    contracts)
    6-7
    Stimulation causes contraction
22
Q

Does ATP connect or release actin-myosin cross-bridges?

23
What role does SERCA (Sarcoplasmic / Endoplasmic Reticulum Ca2+ ATPase) play in muscle relaxation?
Membrane transport protein that uses ATP to pump calcium ions from the cytosol back into the sarcoplasmic reticulum. * Muscle relaxes
24
How does phosphocreatine act as a energy storage molecule?
transfers a phosphate molecule to ADP during strenuous exercise when ATP levels are low. -This releases an ATP and a Creatine molecule
25
What 4 things define slow vs fast twitch muscle?
1 Aerobic vs Anaerobic respiration use Anerobic produces lactic acid (muscle burning feeling) 2. Myoglobin levels -Myoglobin provides oxygen to cells. 3. Mitochondria number 4. Myosin isoforms
26
A cell with high myoglobin, uses aerobic respiration, would have myosin isoforms that break down ATP fast or slow?