Biochem 2 Final--Vitamins Flashcards Preview

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Flashcards in Biochem 2 Final--Vitamins Deck (51)
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1
Q

What is the street name for B1

A

Thiamine

2
Q

What is the coenzyme form of B1

A

TPP

3
Q

What is the general role of B1

A

Oxidative decarboxylation

decarboxylase enzyme

4
Q

What are the deficiencies associated with B1

A

Beri-Beri

Wernicke-korsakoff syndrome

5
Q

What is the street name for B2

A

Riboflavin

6
Q

What is the coenzyme form of B2

A

FAD and FMN

7
Q

What is the general role of B2

A

oxidation-reduction and dehydrogenase enzyme

8
Q

What is the deficiencies associated with B2

A

Angular stomatis, corneal vascularization and cheilosis

9
Q

What is the coenzyme form of B3

A

NAD+

NADP+

10
Q

What is the general role of B3

A

Vasodilator, Glycolysis, KC, electron carrier, H+

11
Q

What are the deficiencies associated with B3

A

Pellegra (Dementia, Dermatitis, Diarrhea)

12
Q

What is the street name for B5

A

Panthothenate

13
Q

What is the coenzyme form of B5

A

Coenzyme A

14
Q

What is the general role of B5

A

activation rxn and acyl carrier (acetyl-coa fat synthesis)

15
Q

What deficiencies are associated with B5

A

rare–present in most food

16
Q

What is the street name of B6

A

Pyroxidine

17
Q

What is the coenzyme form of B6

A

PLP

PMP

18
Q

What is the general role of B6

A

Transamination, decarboxylations, deaminations

glu -> Gaba, Trp -> serotonin, Gly - heme

19
Q

What are the deficiencies associated with B6

A

seizures
anemia
neuropathies
seborrheic derm

20
Q

What is the street name of B7

A

Biotin

21
Q

What is the coenzyme form of B7

A

Biotin

22
Q

What is the general role for B7

A

transfer CO2

carboxylase enzymes

23
Q

What conditions are associated with B7

A

dermatitis and enteritis

24
Q

What is the street name for B9

A

Folate

25
Q

What is the coenzyme form of B9

A

THF

26
Q

What is the general role of B9

A

one carbon transfer
maturation of RBC
AA interconversion
purine/pyrimidine synth

27
Q

What conditions are associated with B9

A

megaloblastic anemia (enlarged cells die in bone marrow)

28
Q

What is the street name of B12

A

cobalamin

29
Q

What is the coenzyme form of B12

A

2 methyl cobalamine

deoxyadenosyl

30
Q

What is the general role of B12

A

one carbon transfer
isomerization of methyl malonyl
CoA to succinyl CoA
Maturation of RBC

31
Q

What are the conditions associated B12

A
pernicious anemia (lack of intrinsic factor)
Dietary deficiency (not enough dietary B12)
32
Q

What is the street name for C

A

ascorbic acid

33
Q

What is the coenzyme form of C

A

L-dehydroascorbic acid

34
Q

What is the general function of C

A

Reducing agent
wound healing
carnitine/hormone/AA formation
collagen synth

35
Q

What are the deficiencies with C

A

scurvy

poor wound healing

36
Q

What is the street name of A

A

retinol

37
Q

What is the coenzyme form of A

A

retinal

retinoic acid

38
Q

What is the general role of A

A

formatin of rhodopsin

cis-trans conversion of retinal

39
Q

What deficiencies for are associated with A

A
night blindness
dry skin
perifollicular hyperkeratosis
xerophathalmia 
keratomalacia
40
Q

What is the street name of D

A

cholecalciferol (D3 w/sun)

ergocalciferol (D2 w/milk)

41
Q

What is the conenzyme form of D

A

25-OH(Storage form) DHCC

1,25 (active form)

42
Q

What is the general role of D

A

regulates Ca++ levels

43
Q

What is the deficiencies with D

A

Rickets
osteomalacia
hypocalcemic tetany

44
Q

What is the street name of K

A

phylloquinone

45
Q

Whatis the coenzyme form of K

A

prothrombin II

46
Q

What is the general role of K

A

cofactor for carboxylations of glutamic acid

47
Q

What is associated with K deficiency

A

hemorrhage

48
Q

What is the street name of E

A

Tocopherols

49
Q

What is the coenzyme form of E

A

alpha-tocopherol

50
Q

What is the general role of E

A

antioxidant, decrease free radicals, protects against lipid peroxidation

51
Q

What is associated with deficiency in E

A

tendency to bleed