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Nutrition > Biochemical assessment > Flashcards

Flashcards in Biochemical assessment Deck (29):
1

nutrient assessment

determine rate of function by analyzing enzymes and/or metabolites

2

organic acids

energy/mitochondrial fx
b-complex vitamin markers
methylation pathway markers
neurotransmitter metabolism markers
oxidative damage/antioxidant markers
detoxification markers
intestinal dysbiosis markers

3

test for serotonin metabolism

5-hydroxyindoleacetate (5-HIA) in urine
= end product of serotonin metabolism
incr with tryptophan, SSRIs, 5-HTP supplementation
decr when metabolic precursors = deficient or low B6

4

test for methylation

methylmalonic acid and/or SAMe
B12 dependent enzyme = methylmalonic CoA mutase

5

test for central energy metabolism

lactate (function of PDH and availability of its cofactors)
beta-hydroxybuterate

6

Thiamin (B1)

erythrocyte transketolase (ETK)
thiamin in serum or whole blood

7

Riboflavin (B2)

glutathione reductase

8

Niacin (B3)

N-methylnicotinamide in 24 hr urine

9

Pantothenate (B5)

whole blood or urine pantothenate

10

Pyridoxine (B6)

erythrocyte glutamate-pyruvate transaminase (EGPT)
amino acid profile (plasma or urine)
urine kynurenic and xanthurenic acid following tryptophan load

11

Folic acid

serum folate
24 hr urine formiminoglutamic acid
homocysteine

12

Vitamin B12

methylmalonic acid
serum B12

13

Biotin (B7)

whole blood biotin
fatty acid abnormalities

14

Vitamin C

whole blood/serum/WBC vitamin c

15

Vitamin A

plasma retinol
retinol binding protein

16

Vitamin E

alpha-/beta-/gamma tocopherol in serum or plasma

17

Vitamin K

prothrombin time
clotting time

18

Calcium

RBC calcium
whole blood calcium
(not an easy mineral to asses)

19

Chromium

RBC chromium
HgA1C

20

Copper

RBC copper
serum ceruloplasmin

21

Iron

serum binding iron
serum ferritin
% transferrin saturation
total iron binding capacity (TIBC)

22

Magnesium

RBC or WBC Mg
Mg load test

23

Manganese

RBC/whole blood/hair Mn

24

Molybdenum

hair Mo
urine sulfite

25

Potassium

serum/RBC/whole blood

26

Selenium

whole blood
RBC glutathione peroxidase
hair Se

27

Sodium

serum Na

28

Sulfur

urine sulfate
sulfide
sulfate:creatinine ratio
amino acids incl: methionine, cysteine, taurine (plasma or urine)

29

Zinc

WBC
oral zinc
urine amino acids