Biochemistry of Alcohol Flashcards Preview

Year 2 CLASP Alcohol > Biochemistry of Alcohol > Flashcards

Flashcards in Biochemistry of Alcohol Deck (9)
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1

What tests you can do to see if someone drinks alcohol chronically?

GammaGT
MCV
Triglycerides

2

Why is gammaGT raised in chronic alcohol consumption?

It is a pathway that is induced to breakdown excess alcohol.

3

Why is there a raised MCV in alcoholics?

Unknown.

4

Why are there raised triglycerides in chronic alcohol excess?

Due to increased synthesis in the liver.

5

What is the simplest formula for serum osmolality?

2 x [Na]
Concentration of sodium is much higher than everything else.

6

What is the reference interval for serum osmolality?

275-295mmol/kg

7

What is the gap between calculated and measured osmolality?

The osmolal gap (measured - calculated)

8

What does it mean when there is an osmolal gap?

There is something else in the patient's blood contributing to the osmolality.

9

What kind of acidosis will methanol cause?

A metabolic acidosis (low bicarbonate).