biological membranes Flashcards

(50 cards)

1
Q

describe the structure of a phospholipid

A

phosphate head- soluble in water, hydrophilic and polar
fatty acid tails- insoluble, hydrophobic and non-polar

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2
Q

give 3 roles of cell membranes

A

barrier between internal and external environment
location of chemical reactions
protection

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3
Q

why hydrophobic molecules (e.g. steroids) pass through the membrane easily

A

phospholipid bilayer is hydrophobic

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4
Q

why can water molecules pass through easily even though they are polar

A

they are extremely small

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5
Q

why does cholesterol increase the strength of the cell surface membrane

A

polar, hydrophilic group attracts polar phosphate heads in the phospholipids
non-polar, hydrophobic groups attracts non-polar fatty acid tails in the phospholipids

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6
Q

give 2 advantages of cholesterol

A

maintains fluidity of membrane
maintains strength
reduces the movement of water soluble chemicals

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7
Q

why is it called the fluid mosaic model

A

fluid- phospholipids can move around (flexible and can change shape)
mosaic- arrangements of proteins vary

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8
Q

what are intrinsic proteins

A

embedded in the membrane from one side to the other

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9
Q

how are intrinsic proteins hydrophobic

A

they have hydrophobic amino acid groups on the outside surface of the protein which interact with the hydrophobic fatty acid tails

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10
Q

what are the 2 types of intrinsic proteins

A

channel proteins
carrier proteins

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11
Q

what is the role of channel proteins

A

allow water soluble molecules and ions to diffuse through

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12
Q

why do channel proteins allow water soluble molecules to diffuse through

A

the central pore is lined with hydrophilic amino acids

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13
Q

what is the role of carrier proteins

A

they change tertiary shape or position to transfer ions or molecules from one side of the membrane to another side

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14
Q

give 3 roles of extrinsic proteins

A

structural role
act as enzymes
receptors (e.g. hormones)

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15
Q

how are extrinsic proteins different to intrinsic proteins

A

extrinsic don’t span the membrane whereas intrinsic proteins do

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16
Q

what are glycoproteins

A

carbohydrate molecule attached to the protein

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17
Q

give 3 roles of glycoproteins

A

allow cells to attach to each other (to make tissues)
present antigens
receptors for hormones

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18
Q

what are glycolipids

A

carbohydrate molecule attached to the phospholipid

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19
Q

give 3 roles of glycolipids

A

antigens
recognition

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20
Q

define diffusion

A

the net movement of molecules from a region of higher concentration to a region of lower concentration down a concentration gradient

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21
Q

why is diffusion a passive process

A

no metabolic energy is required to take place

22
Q

give 6 factors that affect the rate of diffusion

A

concentration gradient
particle size/charge
temperature
surface area
distance
presence of carrier/channel proteins

23
Q

why does particle charge affect the rate of diffusion

A

ions with a charge will not pass through the membrane due to the hydrophobic core

24
Q

why does temperature affect the rate of diffusion

A

particles have more kinetic energy

25
what happens in facilitated diffusion
hydrophilic substances pass through the cell membrane through intrinsic proteins (carrier and channel proteins)
26
give 2 key facts about protein channel
they are selective of the chemical it passes through some are constantly open and others open via a trigger
27
is facilitated diffusion passive?
yes
28
what protein is used in active transport
carrier proteins
29
define active transport
the net movement of molecules from a region of low concentration to a region of high concentration against a concentration gradient
30
is active transport passive
no
31
how is metabolic energy is required
ATP
32
how does active transport work
molecule attaches to a receptor site on a carrier protein ATP undergoes hydrolysis creating ADP and phosphate ATP binds to the carrier protein causing it to change shape the changing of shape causes it to transport the molecule so it can leave via the other end of the membrane where it is released
33
what are product after ATP is hydrolysed
ADP and phosphate
34
why do we find a lot of mitochondria in cells that perform a lot of active transport
active transport uses a lot of ATP
35
define osmosis
the movement of water molecules from a region of higher water potential to a region of lower water potential through a partially permeable membrane
36
what water potential is pure water
0
37
what is the unit of water potential
kPa
38
what is water potential a measure of
pressure
39
what is the highest possible water potential
0
40
define hypertonic
lower solute concentration in the inside than on the outside, causing water to leave the cell to a higher concentration of water
41
what can hypertonic lead to
plasmolysis (shrivelled up)
42
define hypotonic
higher solute concentration in the inside than the outside, water enters cells where there is a higher concentration of water
43
what can hypotonic lead to
cytolysis
44
define isotonic
equilibrium
45
what do both endocytosis and exocytosis transfer
large quantity of material (bulk transport)
46
what is phagocytosis
when solid materials are taken in by endocytosis
47
what is pinocytosis
when liquid materials are taken in by endocytosis
48
what is endocytosis
material into the cell
49
what is exocytosis
material out of a cell
50
are endocytosis and exocytosis passive
no- they require energy