Biopharmaceutics (1)

Question 1

Biopharmaceutics

Answer 1

Study of the properties of therapeutic substances + their dosages/bioactivity relationships

Question 2

Reasons why people live longer (in terms of therapeutic drugs)

Answer 2

Prescription drugs +Natural health products, vaccines, Diagnostics and workplace infrastructure

Question 3

Prescription Drugs

Answer 3

Small molecules -peptides or proteins

Question 4

Why are proteins not used in drugs very often? What can be used instead?

Answer 4

• Has very shot half-life.. Our body breaks down proteins very efficiently
• Synthetic amino acids can be used

Question 5

Insulin + therapeutic drugs

Answer 5

acts like therapeutic drugs even though it is very large

Question 6

How do prescription drugs get excreted?

Answer 6

Urine

Question 7

Function of Vaccines/conjugates

Answer 7

Immunity and protection of illnesses

Question 8

Worst case scenario for vaccines/conjugates + how to prevent it?

Answer 8

• could get sick when pathogen that was used in the vaccination is obtained
• Put protein on a pathogen so that body can detect it – body breaks down proteins

Question 9

What are natural health products?

Answer 9

Vitamins, Plant extracts

Question 10

Grapefruit + pills

Answer 10

• it can affect the liver metabolism of a drug… pill stays longer in the body = overdosage

Question 11

Diagnostics

Answer 11

• Improved medical procedures and early detections

- ex. cameral pill or endoscopies(takes pictures as it goes through the body)

Question 12

Pharmaceutical Sciences

Answer 12

• group of interdisciplinary areas of research that are involved with the design, synthesis, mode of action, delivery and use of drugs

Question 13

Industry of pharmaceutical science purpose

Answer 13

Supply materials or techniques that (promise to) deliver the things people desire the most

Question 14

What drugs are in demand (2015-present)

Answer 14

• Mental health
• Cholesterol lowering
• hypertension (blood lowering)
• • These are easily changed with lifestyle/diets but people prefer quick resolution to their problems (the need to spend $$$)

Question 15

Popular/in demand drugs

Answer 15

• Lipitor (cholesterol lowering)
• Plavix (blood thinner)
• Nexium (reduces stomach acid)
• Advair (asthma)
• Abilify (mental health - schizophrenia)

Question 16

Most prescribed drugs (3 examples)

Answer 16

1. Hydrocodone (attaches to opinoid receptors - treats mild pain, coughs or diarrhea)
2. Zocor (lowers cholesterol)
3. Lisinopril (lowers blood pressure)

Question 17

Top selling drugs/in demand (top 5 in 2010)

Answer 17

1. Lipitor (cholesterol lowering)
2. Nexium (proton pump inhibitor - decreases stomach acid)
3. Plavix (Blood thinner- prevents blood clots)
4. Advair (asthma)
5. Abilify (antipsychotic medication - schiz)