Biopsychology Flashcards

1
Q

What is the human nervous system made up of

A
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2
Q

Function of the brain

A

Main job is to ensure that life is maintained
There are many parts of the brain
Some connected with vital functioning and others which are involved in processes such as problem solving and higher order thinking

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3
Q

What is the spinal cord

A

Facilities the transferral of messages to and from the brain to the PNS
Also involved in reflex action

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4
Q

What is the peripheral nervous system

A

The PNS transmits messages via millions of neurons (nerve cells), to and from the central nervous system

PNS is further sub-divided into:
The somatic nervous system (SNS)
The autonomic nervous system (ANS)

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5
Q

What does the central nervous system include

A

Brain and spinal cord

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6
Q

What is the somatic nervous system

A

The part of the PNS that is responsible for carrying sensory and motor information to and from the spinal cord
Controls conscious activities

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7
Q

What is the autonomic nervous system

A

The governs vital functions in the body such as breathing, heart rate, digestion, sexual arousal and stress responses (fight or flight)
Controls unconscious activities

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8
Q

Difference between sympathetic and parasympathetic nervous system

A

Sympathetic: fight or flight to prepare the body to expend energy
Parasympathetic: rest and digest to maintain body energy and functions
These are antagonistic and work oppositely

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9
Q

Functions of sympathetic vs parasympathetic systems

A
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10
Q

What is a gland

A

An organ in the body that synthesises and secretes substances such as hormones

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11
Q

What is a hormone

A

Chemical substances that circulate in the bloodstream, their effects on behaviour can be very powerful

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12
Q

What is homeostasis

A

The maintenance of a constant internal environment within the body

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13
Q

What does the pineal gland in the endocrine system

A

Produces and secretes he hormone melatonin which regulates biological rhythms such as sleep and wake cycle
Found in the brain

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14
Q

What does the pituitary gland do in the endocrine system

A

The master gland as it controls the release of hormones from all the other endocrine glands in the body
Found in the brain
Controlled by the hypothalamus
Made up of anterior (front) and posterior (back) pituitary gland

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15
Q

What does the thyroid gland do in the endocrine system

A

Produces hormones that regulate the body’s metabolic rate, as well as heart and digestive function, muscles control, brain development and mood
Found in the throat

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16
Q

What do the adrenal glands do in the endocrine system

A

Release adrenaline directly into the bloodstream from adrenal medulla which prepares the body for fight or flight by constricting blood vessels to the stomach
This inhibits digestion and increases the heart rate
Found above the kidneys
Made up of adrenal cortex (outer) and adrenal medulla (inner)

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17
Q

What do the testes do in the endocrine system

A

This facilitates the release of the male hormones - testosterone

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18
Q

What do the ovaries do in the endocrine system

A

This facilitates the release of the female hormones - oestrogen and progesterone

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19
Q

What is the endocrine system

A

One of the body’s major information systems that instructs glands to release hormones directly into the bloodstream
The hormones are released slowly and help to control slower processes such as cell growth
Provides a system of chemical communication through the bloodstream

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20
Q

What cells do hormones affect

A

Target cells

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21
Q

Negative evaluation of the endocrine system: gender bias

A

There are gender differences in how males and females respond to stress:
Taylor found that men usually react to stress with a ‘fight or flight” response but women may show a ‘tend and befriend’ response

Oxytocin (a hormone secreted in both men and women) as a response to stress has been shown to make people les anxious and more sociable

However, male hormones reduce the effects of oxytocin but female hormones oestrogen amplifies it

Therefore, men are more vulnerable to the adverse health effects of stress and more likely to develop stress related disorders (hypertension and CHD)

In contrast, women are more likely to ‘tend and befriend’ and this may protect women against stress and this may explain why women live on average 7 1/2 years longer than men

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22
Q

Negative evaluation of the endocrine system: reductionist

A

The physiological approach is reductionist
A person’s response depends on a number of different factors
These include the type of stressor involved and the way the person interprets (cognitively) the threat
This suggests that this approach may present an oversimplified explanation

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23
Q

Sensory neurone

A

Unipolar neurons - only transmit messages
Carries messages from the PNS to the brain and spinal cord
Long dendrites and short axons

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24
Q

Relay neurone

A

Multipolar neurons - send and receive messages
Transfers messages from sensory neurons to other interconnecting neurons or motor neurons
Short dendrites and short or long axons

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25
Q

Motor neurone

A

Multipolar neurons - send and receive messages
Carries messages from the CNS to effectors such as muscles and glands
Short dendrites and long axons

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26
Q

Process of synaptic transmission

A

Nerve impulse travels down an axon
Nerve impulse reaches synaptic terminal
This triggers the release of neurotransmitters
Neurotransmitters are fired into synaptic gap
Neurotransmitter binds with receptors on the dendrite of the adjacent neuron
If successfully transmitted the neurotransmitter is taken up by the post-synaptic neuron
The message will continue to be passed in this way via electrical impulses

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27
Q

Labelled motor neurone

A
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28
Q

What happens in a reflex arc

A

In a reflex arc (like the knee jerk reflex) a stimulus (e.g a hammer hitting the knee) is detected by sense organs in peripheral nervous system
These convey a message along a sensory neuron
The message reaches the nervous system where it connects with a relay neuron
This then transfers the message to a motor neuron
Message is carried to an effector such as a muscle, which cause the muscle to contract and, hence, the knee to move

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29
Q

When does an action potential occur

A

An action potential occurs when a neuron sends information down an axon, away from the cell body
This action potential is an explosion activity - means that some event (a stimulus) causes the resting potential to move forward

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30
Q

What does a reflex arc help to happen

A

Reflex arcs occur automatically
They bypass the conscious brain and allows the action to happen rapidly to avoid damage

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31
Q

Label the diagram

A
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32
Q

What is a synapse

A

The gap between the end of one neuron and the dendrites of the next neuron

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33
Q

What are neurotransmitters

A

Chemicals that are released from a synaptic vesicle into the synapse by neuron
They affect the transfer of an impulse to another nerve or muscle
They can either be excitatory or inhibitory

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34
Q

Where are neurotransmitters taken back up into

A

They are taken back up into the terminal buttons of neurons through the process of reuptake
Can also be broken down by an enzyme

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35
Q

What are some neurotransmitters that are excitatory only

A

Acetylcholine (ACH)
Adrenaline

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36
Q

What are some neurotransmitters that are inhibitory only

A

Serotonin
GABA

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37
Q

Differences between excitatory or inhibitory synaptic connections

A

Excitatory: make it more likely the next neuron will fire (such as acetylcholine
Inhibitory: they make it less likely the next neuron will fire (such as GABA)

Synaptic connections can be excitatory or inhibitory - the difference lies in the action of the neurotransmitter at the postsynaptic receptor

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38
Q

How do the types of neurotransmitters at synaptic maintain brain function

A

Normal brain functions depends upon a regulated balance between excitatory and inhibitory influences

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39
Q

What happens with an excitatory neurotransmitter

A

If neurotransmitter is excitatory then the post synaptic neuron is more likely to fire an impulse as the neurotransmitter increases the positive charge (once the positive charge reaches threshold, depolarisation occurs and the post synaptic neuron fires)

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40
Q

What happens with an inhibitory neurotransmitter

A

If the neurotransmitter is inhibitory then the post synaptic neuron is less likely to fire an impulse as it increases the negative charge (the neurotransmitter needs to keep the charge below threshold so that depolarisation does not occur and thus the post synaptic neuron will not fire)

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41
Q

What happens when both types of neurotransmitters are released from a synaptic vesicle

A

The excitatory and inhibitory influences are summed, if the net effect on the postsynaptic neuron is inhibitory, the neuron will be less likely to fire and if the net effect is excitatory, the neuron will be more likely to fire

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42
Q

What is localisation and when was it discovered

A

Localisation: the theory that specific areas of the brain are associated with particular physical and psychological functions

During the 19th century it was discovered that certain areas of the brain held particular functions
This is known as localisation of brain function

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43
Q

What does Broca’s area do

A

Broca: this is responsible for converting thought into speech

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44
Q

What does wernicke’s area do

A

Wernicke: plays an important role in understanding other people’s speech and for producing speech which makes sense

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45
Q

What does damage to Broca’s or Wernicke’s area result in

A

Damage to either of these areas would result in aphasia - inability (or impaired ability) to understand or produce speech

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46
Q

What is hemispheric lateralisation

A

Hemispheric lateralisation: the dominance of one hemisphere of the brain for particular physical and psychological functions

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47
Q

How is the brain divided

A

Divided into left and right hemispheres where each hemisphere is responsible for specific actions
Both sides a largely similar but language areas are only found on the left side

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48
Q

What does the central core do

A

This regulates out most primitive and involuntary behaviours such as breathing, sleeping or sneezing
Known as the brain stem
Includes structures such as the hypothalamus - in the midbrain
It regulates eating and drinking as well as regulating the endocrine system in order to maintain homeostasis

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49
Q

What is homeostasis

A

Homeostasis: the process by which the body maintains a constant physiological state

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50
Q

What does the limbic system do

A

This controls our emotions
Around the central core of the brain, interconnected with hypothalamus, it contain structures such as the hippocampus; key roles in memory

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51
Q

What does the cerebrum do

A

This regulates our higher intellectual processes
It has an outermost layer known as the cerebral cortex; appears grey because of the location of cell bodies (hence “grey matter”)
Each of our sensory systems sends messages to and from this cerebral cortex
The cerebrum is made up of the left and right hemispheres which are connected by a bundle of fibres called the corpus callosum

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52
Q

Frontal lobe function

A

Frontal lobe: the location for awareness of what we are doing within our environment (our consciousness)

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53
Q

Temporal lobe function

A

Temporal lobe: location for the auditory ability and memory acquisition, responsible for analysis of speech based information

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54
Q

Occipital lobe function

A

Occipital lobe: location for vision

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55
Q

Parietal lobe function

A

Parietal lobe: location for sensory and motor movements
Somatosensory located in parietal lobe responds to heat, cold, touch, pain and our sense of body movement

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56
Q

What happens during Broca’s aphasia

A

Responsible for speech production
Damage means that you are able to speak but comes out as nonsense and grammatically incorrect

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57
Q

What happens during Wernicke’s aphasia

A

Language comprehension
Damage means you can hear what someone is saying but cannot understand

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58
Q

Positive evaluation of localisation of brain function: brain scan evidence

A

There is a wealth of evidence providing support for the idea that many neurological functions are localised, particularly in relation to language and memory

Petersen used brain scans to demonstrate how Wernicke’s area was active during a listening task and Broca’s area was active during a reading task, suggesting that these areas of the brain have different functions

There now exists a number of highly sophisticated and objective method for measuring activity in the brain which provide sound scientific evidence for localisation of brain function

Tulving suggested semantic memories resided in left prefrontal cortex, episodic memories in right prefrontal cortex, procedural in cerebellum

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59
Q

Positive evaluation of localisation of brain function: neurosurgical evidence

A

Most extreme treatment as it involves the destruction of healthy brain tissue:
Lobotomy: removal of brain tissue
Leucotomy: cutting the connections to a particular part of the brain

Neurosurgery is still used today for treatment - resistant severe depressives and extreme cases of OCD

The success of these procedures strongly suggests that symptoms and behaviours associated with serious mental disorders are localised

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60
Q

Positive evaluation of localisation of brain function: case study evidence

A

Phineas gage
Gage suffered blast injury in a mine where an iron pole was pushed through his left cheek and behind the left eye and exited the brain and skull from the top of his head
Survived but changed from efficient foreman with a well balanced mind, and a shrewd business man with a kind and reserved personality to now a boisterous, rude and grossly blasphemous
Damasio said he taught us a lot about the complexity of psychological processes that occur in the human brain

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61
Q

Negative evaluation of localisation of brain function: high cognitive functions are not localised

A

The work of Karl lashly suggest that the basic motor and sensory functions were localised, but that higher mental functions were not

Rats had 10%-50% of their cortex removed. No area was shown to be more important than any other area of a rats ability to learn a maze

The process of learning appeared to require every part of the cortex, rather than being confined to a particular area

This seems to suggest that learning is too complex to be localised and requires the involvement of the whole brain

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62
Q

Negative evaluation of localisation of brain function: how is neuroplasticity a criticism of localisation of the brain?

A

Cortical remapping: the brain is able to reorganise itself in an attempt to recover the lost function

Lashley ‘the law of equipotentiality’ - surviving brain circuits help out so the neurological function can be achieved
So function not limited to one area of brain

63
Q

What is denervation

A

Denervation: loss of nerve supply. Inactivity and atrophy of muscle fibres

64
Q

What is plasticity

A

Plasticity: the brain’s tendency to change and adapt as a result of experience and new learning

65
Q

What is denervation supersensitivity

A

Denervation supersensitivity/ Denervation hypersensitivity is the sharp increase of sensitivity of post synaptic membranes to a chemical transmitter after denervation.
It is a compensatory change

66
Q

How does plasticity work after trauma

A

New nerve endings grow and connect with undamaged areas through axonal sprouting

Brain is able to rewire and reorganise by forming new synaptic connections close to the area of damage
Secondary neural pathways that would not typically be used to carry out certain functions are ‘unmasked’ to enable functioning to continue
This process is supported by a number of structural changes

Can also be done through recruitment of homologous areas where areas on the opposite hemisphere take up specific tasks.
E.g. if Broca’s area was damaged then an area on the right might take over

67
Q

What half of the brain are both Broca and Wernicke’s areas located

A

Left hemisphere (where language resides)

68
Q

How does plasticity work

A

Information takes a pathway through the brain
Travels from one neuron to the next via synapses
When we are presented with new information, new neural pathways begin to form
Using a neural pathway strengthens it as the connection between neurons get stronger
If a neural pathway is not used it weakens

69
Q

Method of Elberts study of plasticity in musicians

A

9 musicians who played strings instruments were compared to 6 non-musicians
Magnetic source imaging was used to measure the area of the somatosensory cortex representing the digits of the left hand of ppts
(Left hand is key in playing strings instruments proficiently)

70
Q

Results of Elberts study of plasticity in musicians

A

Area of the somatosensory cortex representing digits of the left and was larger in the stringed instrument players than in controls

71
Q

Conclusion of Elberts study of plasticity in musicians

A

Findings suggest that the increased amount of sensory processing required from the left hands of the musicians resulted in structural changes in the brain
Provides support for plasticity

72
Q

Evaluation of Elberts study of plasticity in musicians

A

Researchers argue that the increased representation of the left hand digits in the musicians may have been genetic rather than the result of playing the instrument
Meaning they may have good because of natural traits
Study used small sample size so may not be representative

73
Q

Positive evaluations of plasticity: evidence of plasticity in motor cortex

A

Nudo mapped motor cortex of adult monkeys beforr and after training in a task which required use of finger digits
Found that the representation of the digits in the motor cortex increased
Mapped out training task mainly using forearm and found the representation of this increased and digit representation decreased
Suggests that the plastic changes are continuous and reversible in monkeys

74
Q

What is synaptic pruning

A

During infancy the brain experiences rapid growth in synaptic connections (twice as many as an adult brain)
As we age the rarely used connections are deleted and frequently used connections are strengthened
This is synaptic pruning

75
Q

When may neural plasticity not work

A

Prolonged damage to an area of the brain will result in less rewiring and repair

76
Q

How does the brain use plasticity to functionally recover from trauma

A

Increased brain stimulation: if neurons are damaged, neighbouring neurons are also affected (works the same for the hemispheres)
Therefore, you need to stimulate the undamaged neighbouring neurons or healthy hemisphere to aid plasticity
After trauma, this can happen very quickly (spontaneous recovery) and then it slows down

77
Q

Evidence for brain recovery using plasticity

A

Case of Gabby Giffords
Gunshot wound to head
Survived shooting
Bullet only went through one hemisphere
Brain was able to rewire to allow speech and normal functioning through functional recovery

78
Q

Positive evaluation of using the affected area for recovery from brain damage

A

CIMT (Constraint-induced movement therapy)
Can be applied to aphasia patients recovering from a stroke
Patients try to speak a word on a card instead of trying to communicate in other ways
Studies have shown this to cause dysfunctional areas near the damaged area to work again

79
Q

Negative evaluation of using the affected area for recovery from brain damage

A

CIMT can be frustrating
Needs to be intensive to be effective
Much harder to regain function if there’s lots of damage to brain

80
Q

Positive evaluation for plasticity: practical application

A

Understanding plasticity has contributed to the field of neuro-rehabilitation
Following illness or injury spontaneous recovery slows down so physical therapy can be used

81
Q

Positive evaluation of using the affected area for recovery from brain damage: animal studies

A

Study involved sewing one eye of a kitten shut and analysing the brain’s cortical responses
Found that the area of the visual cortex associated with the shut eye was not idle but continue to process information from the open eye

82
Q

Negative evaluation of using the affected area for recovery from brain damage: negative plasticity

A

Brain’s bility to rewire itself can have bad behavioural consequences
Prolonged drug use can cause poor cognitive function and risk of dementia
60-80% amputees develop phantom limb syndrome
Sensations are unpleasant and painful and thought to be due to plasticity in the somatosensory cortex

83
Q

What part of the brain connects the two hemispheres

A

The corpus callosum

84
Q

What side of the body does each hemisphere control

A

Each hemisphere generally deals with information from the opposite side of the body
E.g. information in the right visual field (right half of what you see) goes to visual cortex in the left hemisphere and vice versa
Info passes through corpus callosum whichever side of the brain needs to deal with it

85
Q

When may the corpus callosum be severed

A

In severe cases of epilepsy to stop seizures spreading across the brain

86
Q

What can be a result of severing then corpus callosum

A

Information can no longer move between the two hemispheres

87
Q

What is hemispheric lateralisation

A

Where certain activities and behaviours are controlled by one of the two hemispheres of the brain independently

88
Q

Method of sperry’s study on split brain surgery

A

Study involved a combination of case studies and experiments
11 ppts who had had split surgery as a result of severe epilepsy
Control group used who had no hemisphere disconnection

In one experiment, ppts covered one eye and looked at a fixed point on a projector screen
Pictures were projected onto the right or left of the screen at high speeds so that there was no time for eye movement

89
Q

Results of sperry’s study on split brain surgery

A

If the picture was shown in the right visual field all ppts could say or write what it was
However, if image was flashed onto the left, the split brain ppts couldn’t say or write what they’d seen but could select a corresponding object with their left hand
The object selected represented what had been shown to their left eye (right hemisphere)
They did not know why they had selected this object

90
Q

Conclusion of sperry’s study on split brain surgery

A

Shows that different areas of the brain specialise in different functions
Left hemisphere (receiving visual information from the right visual field) can convert sight into spoken and written language
Usually information entering the right hemisphere can cross over to be processed in the left but this can’t happen in split brains so the information going to the right hemisphere can’t be converted into language at all
However, the right hemisphere can still produce a non-verbal response

91
Q

Evaluations of sperry’s study on split brain surgery

A

Sperry used case studies and experiments to obtain qualitative and quantitative data which increased the reliability and validity of the study

Study only used 11 ppts which is a very small sample to be generalised to everyone
However, it would’ve been hard to find more split brain patients to study

Epilepsy is called by brain damage and the patients had been on medication which may have affected their brain
This means it’s hard to conclude that the ways they processed information would be the same for people without epilepsy or split brain treatment

Situation was artificial so study lacks ecological validity

92
Q

Positive evaluation for sperry’s research on split brain: Strengths of methodology

A

Experiments used highly specialised and standardised procedures
The method used was ingenious - typically ppts would be asked to stare at a given point, the ‘fixation point’, whilst one eye is blindfolded
The image projected would be flashed for 1/10 of a second, meaning the split brain patient would not have time to move their eye across the image and so spread the information across both sides of the visual field and both sides of the brain
Sperry was able to develop a useful and well-controlled procedure based off the original research

93
Q

Positive evaluation for sperry’s research on split brain: Demonstrated lateralised brain functions

A

The work into the split brain phenomenon has produced sizeable body of research and conclusions of which appears to be that left hemisphere is more geared towards analytic and verbal tasks, whilst right is more for performing spatial tasks and music
The right hemisphere can only produce rudimentary words and phrases but contributes emotional and holistic content to language
Left hemisphere = analyser
Right hemisphere = synthesiser

94
Q

Negative evaluation for sperry’s research on split brain: theoretical basis

A

Studies have suggested that the two hemispheres are so functionally different that they represent a form of duality in the brain- that in effect we are all two minds and that this is a situation that is only emphasised rather than created in the split brain patient.
In contrast, other researchers have argued that, far from working in isolation, the two hemispheres form a highly integrated system and are both involved in most everyday tasks.

95
Q

Negative evaluation for sperry’s research on split brain: Differences in function may be overstated

A

Sperry’s work overemphasises and oversimplifies the functional distinction between the left and right hemisphere.

Although the verbal and non-verbal labels can, on occasion, be usefully applied to summarise the differences between two hemispheres, modern neuroscientists would contend that the actual distinction is less clear-cut than this.

In normal brain the two hemisphere are in constant communication when performing everyday tasks, and many of the behaviours typically associated with one hemisphere can be effectively performed by the other when the situation requires it.

96
Q

How do fMRI scans work

A

How it works
More oxygenated blood flows to active areas of the brain
Molecules in oxygenated blood respond differently to a magnetic field than those in deoxygenated blood
More active areas of the brain can be identified

97
Q

What does fMRI stand for

A

Functional magnetic resonance imaging

98
Q

What are fMRIs

A

These are 3D scan providing structural and functional information
fMRIs show changes in brain activity using a strong magnetic field and radio waves to measure blood flow in the brain

99
Q

Strengths of fMRIs

A

fMRI provides a high resolution moving picture of brain activity.
This means that patterns of activity can be compared rather than just the physiology of the brain.
Non-invasive/ virtually risk free
Does not rely on radiation

100
Q

Weaknesses of fMRIs

A

Poor temporal resolution- 5 second time-lag behind the image on the screen and the initial firing of neuronal activity.
Expensive and can only capture a clear image if the person stays still.
Can only measure blood flow in the brain. It cannot home in on activity of individuals neurons.

101
Q

Where are EEGs commonly used

A

EEGs are commonly used in sleep studies
Used for studying depression and schizophrenia.
Studies have found people suffering from schizophrenia or anorexia nervosa had abnormal EEG wave patterns compared to controls
EEGs can be used as a diagnostic tool (potentially)

102
Q

What does EEG stand for

A

Electroencephalogram

103
Q

Strengths of EEGs

A

Invaluable in the diagnosis of conditions such as epilepsy.
Contributed to research into ultradian rhythms of sleep
Extremely high temporal resolution- can accurately detect brain activity at a resolution of a single millisecond.
Non invasive procedure

104
Q

Weaknesses of EEGs

A

The main drawback of EEG lies in the generalised nature of the information received (thousands of neurons)
Not useful for pinpointing the exact source of neural activity and does not allow researchers to distinguish between activities originating in different but adjacent locations

105
Q

How do EEGs work

A

Shows overall electrical activity of the brain
Picks up the signal of many neurons firing together
Multiple electrodes are placed on the scalp and the electrical activity in the brain is recorded for a period of time
Produces a pattern of waves that can represent levels of arousal or consciousness

106
Q

What does ERP stand for

A

Event-related potentials

107
Q

What do ERPs do

A

ERPs record activity in response to a stimulus introduced by the researcher.
All extraneous brain activity from the original EEG recording is filtered out leaving only those responses that relate to the specific stimuli.

108
Q

What are ERPs used for

A

Have been used in memory research to give researchers an insight into information processing in the brain
Have been used to show differences in brain activity from people suffering from certain psychiatric disorders
E.g. Miltner found that people with phobias had ERPs of greater amplitude compared to non phobic people

109
Q

Strengths of post-mortem examinations

A

Vital in providing a foundation for early understanding of key processes in the brain.
Broca and Wernicke both used post-mortem studies to establish links between language and the brain.
Improves medical knowledge and helps generate hypotheses for further study

110
Q

Strengths of ERPs

A

Much more specificity to the measurement of neural processes than raw EEG data.
Excellent temporal resolution
Researchers have been able to identify many different types of ERP and describe the precise role of these in cognitive functioning- P300 component is thought to be involved in the allocation of attentional resources and the maintenance of working memory

111
Q

Weaknesses of ERP

A

Lack of standardisation in ERP methodology between different research studies which makes it difficult to confirm findings
To establish pure data, background noise and extraneous material must be completely eliminated

112
Q

What are post mortem examinations

A

Post-mortem examinations involve dissecting the brain of a dead person
This allows researchers to physically look at internal structures of the brain

113
Q

Uses of post mortem examinations

A

If a person had a medical condition when they were alive, a post mortem could show up any structural abnormalities that could explain their condition
E.g: Brown et al. (1986) discovered that patients who suffered from schizophrenia had enlarged ventricles in their brains.

Post mortems have provided evidence for localisation of function in the brain
E.g: Broca carried out post mortems examinations on two patients who developed speech problems as a result of brain damage
Both patients had damage to the same area of the brain, so Broca discovered Broca’s area of the brain

114
Q

Weaknesses of post mortem examinations

A

Causation is an issue with these investigations- observed damage may not be linked to the deficits under review but some other trauma or decay
Ethical issues- patients may not be able to give consent.
For example, the case of HM who lost his ability to form memories and was not able to provide such consent, however post-mortem research has been conducted on his brain.

115
Q

What are circadian rhythms

A

Have cycles that generally occur once every 24 hours
E.g. sleep wake cycle every day

116
Q

What are infradian rhythms

A

Cycle that occur less than once every day
E.g. menstrual cycles

117
Q

What are ultradian rhythms

A

Cycles that occur more than once every 24 hours
E.g. sleep cycle has several repeating stages of light and deep sleep, disrupting these regular sleep cycles can have serious consequences

118
Q

What are the timings of biological rhythms controlled by

A

Controlled by factors both inside (endogenous pacemakers) and outside (exogenous zeitgebers) the body

119
Q

What are endogenous pacemakers

A

These are genetically determined structures and mechanisms within the body which set aspects of biological rhythms

120
Q

What is the SCN

A

Suprachiasmatic nucleus is part of the hypothalamus
Acts as an internal clock to keep the body on an approximate 24-hour sleep wake cycle
Sensitive to light and regulates the pineal gland, which secretes melatonin (induces sleep)

121
Q

How does melatonin secretion work

A

When there is less light, more melatonin is produced
When there is more light, secretion is reduced and waking occurs

122
Q

What are exogenous zeitgebers

A

These are influences outside the body that act as a prompt, these can trigger a biological rhythm

123
Q

What is the most important zeitgeber

A

Light

124
Q

How did Siffre prove that light was an important zeitgeber

A

Spent 6 months in a cave
No clocks and no natural light as zeitgebers
His sleep-waking cycle extended from a 24-hour to a 25-30 hour cycle
It therefore seems that natural light is needed to fine-tune our normal 24-hour cycle

125
Q

Where is an example of how endogenous factors may completely determine a cycle

A

Pengelly and Fisher found that squirrels will hibernate even when kept in laboratory conditions very different from their natural environment

126
Q

How can animals react more flexibly to biological rhythms

A

Human are able to adapt to their surroundings
We can make ourselves stay awake and change the environment to suit our needs e.g. by artificial light

127
Q

How do cultural factors contribute to our understanding of rhythms

A

E.g. eskimos often live in permanent daylight or permanent night time but can maintain regular daily sleep cycles
This means that the cycle cannot be determined by levels of light acting on the pineal gland

128
Q

How can individual differences effect the rhythms

A

Aschoff and Wever found that in a group of people isolated from daylight, some maintained their regular sleep cycles
Other members of the group displayed their own very extreme rhythms e.g. 29 hours awake followed by 21 hours asleep
This also shows that factors must interact to control of influence biological rhythms

129
Q

How can sleep cycles be disrupted

A

This is when exogenous zeitgebers become out of line with endogenous pacemakers

130
Q

How can fast changing exogenous zeitgebers effect our cognition

A

In a natural environment, zeitgebers normally change slowly, e.g. light levels during the year change gradually
Today, zeitgebers can change quickly
These have negative effects on our ability to function which slows reaction times, impairs problem solving skills and limiting our ability to concentrate

131
Q

How can jet lag effect your biological rhythms

A

E.g. travelling from UK to New Yorke, leaving at 9am means arriving at 4pm UK time but it’s 11am US time
Means you’ll feel sleep at an earlier time, sleeping means you’d wake up earlier and be out of sync with local timing. Only way to adapt is to force yourself to stay awake
Takes about a week to fully synchronise to a new time zone
While this is adapting your function and concentration is being impacted

132
Q

How does shift work effect biological rhythms

A

Shift work has been found to desynchronise circadian rhythms, leading to adverse cognitive and physiological effects as workers’ concentration can lapse around 6am whuch increases the rate of accidents
Shift workers also 3x more likely to suffer from heart attacks
Can have economic implications as workers may not work as productively

133
Q

What is phase advance and phase delay

A

Phase delay: changing time zone forwards
Phase advance: changing time zone backwards

134
Q

Negative evaluation for studying biological rhythms: generalisation

A

Findings from animal studies can’t accurately be generalised to human
Humans have greater adaptability
Case study of Siffre was only one person and Aschoff study was conducted on a handful of people

135
Q

Negative evaluation for biological rhythms: poor control within studies

A

Exposure to artificial lights was not controlled in cave studies
Assumed that only natural light has an influence on our biological rhythms but it was later found that dim artificial lighting could adjust the circadian rhythm between 22-28 hours
Means that the sleep wake cycle can be impacted by use of devices such as iPad and phones

136
Q

Positive evaluation for biological rhythms: application to pharmacokinetics

A

Understanding circadian rhythms and their impact on health can determine the best time to administer drug treatments
E.g. risk of heart attack is greatest in early morning so drugs can be taken at night but not released until dusk where they’ll be most effective
Applies to a variety of drugs (cancer, epilepsy etc)

137
Q

Positive evaluation of infradian rhythms: evolutionary basis of the menstrual cycle

A

Evolutionary value of McClintock’s study
May have been advantageous for females to menstruate together and therefore fall pregnant around the same time.
Means that new-borns could be cared for collectively within a social group increasing the chances of offspring’s survival.
Validity can be questioned: Schank argued that if there were too many females cycling together within a social group, it would produce competition for the highest quality males and therefore lowering the fitness of any potential offspring.
The avoidance of synchrony would appear to be the most adaptive evolutionary strategy

138
Q

Positive evaluation of infradian rhythms: evidence supports the idea of distinct stages in sleep

A

Dement and Kleitman measured brain activity using EEG, controlling for effects of caffeine and alcohol.
REM sleep highly correlated with dreaming
Waking people up during the REM stage, people could recall very clearly what they dreamed.
This finding has been replicated on multiple occasions

Replications of this investigation have noted similar findings, though the small size of the original sample has been criticised

139
Q

Positive evaluation of infradian rhythms: animal studies

A

The role of pheromones in animal sexual selection is well documented.
Sea urchins release pheromones into the surrounding water so other urchins in the colony will eject their sex cells simultaneously.
In contrast evidence for the effects of human behaviour remains speculative and inconclusive

140
Q

Positive evaluation of infradian rhythms: practical application

A

One of the most effective treatments for SAD is phototherapy.
Uses light box that simulates very strong light in the morning and evening.
Thought to reset melatonin levels in people who have SAD
However, the placebo effect calls into question the effect of phototherapy

141
Q

Negative evaluation of biological rhythms: methodological limitations in synchronisation studies

A

Stress, lifestyle, diet and exercise can all change a woman’s cycle and these may act as confounding variables.
Suggests that the results of McClinktock’s study would be down to chance.
These studies used small samples and did rely on participants self- reporting.
The study by Trevathan failed to find any evidence of menstrual synchrony.
In this study 29 cohabiting same sex couples kept a daily diary of their cycle, sexual activity and intimate contact

142
Q

Negative evaluation of EP and EZ: beyond the master clock

A

Research has revealed there are numerous circadian rhythms in many organs and cells of the body
Found in the adrenal gland, liver, pancreas, spleen
Although influenced by SCN, they can act independently.
Study demonstrated how changing feeding patterns of mice could alter the circadian rhythms of cells in the liver by up to 12 hours, whilst leaving the rhythm of the SCN unaffected

143
Q

Positive evaluation of EP and EZ: evaluation of exogenous zeitgebers

A

Campbell and Murphy (1998) shone light onto the back of the knees of 15 participants when they woke them at various points in the night.
They managed to vary their sleep cycle by up to three hours

144
Q

Negative evaluation of EP and EZ: ethics in animal studies

A

DeCoursey et al. – animals were exposed to considerable harm and risk when they were returned to their natural habitat

Destroyed the SCN connection in the brain of 30 chipmunks, who were then returned to their natural habitat an observed over 30 days
The sleep wake cycle of the chipmunks disappeared and by the end of the study they were exposed to considerable harm by the end due to predators

145
Q

Negative evaluation of EP and EZ: influence of EZ may be over rated

A

Miles et al. (1997) recount the story of a young man, blind from birth with a circadian rhythm of 24.9 hrs. Despite exposure to social cues, his sleep wake cycle could not be adjusted , and consequently, he had to take sedatives at night and stimulants in the morning to keep pace with the 24 hour world

146
Q

Negative evaluation of EP and EZ: methodological issues

A

Campbell and Murphy’s study has yet to be replicated. However researchers have been critical of the manner in which the study was conducted and have suggested that there may have been some light exposure to participants’ eyes- a confounding variable
• Isolating one zeitgeber does not give insight into the many other zeitgebers that influence the sleep/wake cycle and the extent to which they interact

147
Q

What is the menstrual cycle

A

Occurs every 28 days
Ovulation window of 14 days
Regulated by pituitary gland

148
Q

How did McClintock test whether menstrual cycles can be synchronised

A

Soaked sweat from a woman with a cotton swab under the armpit
Added ethanol and froze the sweat then applied it under other women’s noses to expose them to other pheromones
Found that the ppts menstrual cycles synchronised with the armpit swab

149
Q

Symptoms of SAD

A

The main symptoms are persistent low mood alongside a general lack of activity and interest in life

150
Q

What is SAD

A

A depressive disorder where the onset is related to seasons
Some people can become depressed in the winter months
This is because lack of light causes melatonin to be secreted for a longer time
Melatonin can affect serotonin levels which results in symptoms of depression

151
Q

How is SAD a circannual rhythm

A

melatonin is secreted for a longer period of time due to lack of light.
This is thought to have an effect on the neurotransmitter serotonin, creating depressive symptoms

152
Q

Stages of sleep

A

Stage 1: non REM sleep, the transition of wakefulness to sleep.
Marked by slowing heartbeat, breathing, eye movements and relaxing of muscles
Stage 2: non REM sleep includes slow alpha waves and deeper (theta waves)
Stage 3: involves delta waves (slower), transition into deep sleep
REM: body is paralysed and brain activity speeds up significantly, rapid eye movement, correlates with dreaming

153
Q

Function of adrenaline

A

Prepares body for fight or flight
Increases heart rate
Diverts blood away from skin, kidneys and digestive system
Increases respiration and sweating
Increases blood and oxygen to brain (for planning) and skeletal muscle

154
Q

Why can signals from neurons only travel in one direction

A

Vesicles containing neurotransmitter are only released from pre-synaptic membrane
Receptors for neurotransmitters only present on postsynaptic membrane
Neurotransmitter bind to trigger information to be passed onto next neuron
Neurotransmitters only diffuse from high to low concentration across synaptic gap