Biopsychology Flashcards
(38 cards)
Localisation and function of the brain - holistic vs localisation theory
- knowledge
- holistic vs localisation theory : - in the 19th century scientists broca and werner discovered that particular parts of the brain were associated with particular physical and psychological functions
- before this it was generally believed by scientists about the holistic theory - this was the idea that all parts of the brain were involved with processing thoughts and actions.
- broca and wernicke argued for localisation of function - idea that different parts of the brain performed different tasks and were associated with different parts of the body
- if these certain areas became damaged due to illness or injury, then these functions would be affected.
localisation and function of the brain -hemispheres of the brain
- knowledge
- main part of the brain is known as the cerebrum
- this is divided into two symmetrical halves known as the left and right hemispheres
- lateralisation - idea that some physical and psychological functions are controlled or dominated by particular hemispheres
- activity on left hand side of body = controlled by right hemisphere and vice versa.
localisation and function of the brain - motor, somatosensory, visual and auditory centres
- knowledge
- cerebral cortex - outside layer of both hemispheres
- subdivided into 4 centres known as lobes of the brain - parts of organs which are separated by some way from the rest and each lobe is associated with a specific function
- frontal lobe : - back , motor area, controls all voluntary movement in the opposite side of the body, damage to it can cause the loss of control over fine movements
- parietal lobe : - front, somatosensory area , separated from the frontal lobe by the valley known as the central sulcus, represents sensory information from the skin - amount of area devoted to a body part denotes its sensitivity
- occipital lobe : - visual area / visual cortex, each eye sends information from the right visual field to the left visual cortex and the left visual field to the right visual cortex, damage to the left hemisphere can produce blindness in the right visual fields of both eyes
- temporal lobe : - auditory area, analyses speech - based information, damage to it can cause partial hearing loss or damage to more specific areas such as wernickes area can affect ability to comprehend language
localisation and function of the brain - language centers of the brain
- knowledge
- language is restricted to only the left hand side of the brain
- 1880s - brocas area was developed - left frontal lobe and is responsible for speech production
- damage to it causes brocas aphasia which is chatacerised by speech which is slow, laborious or lacking in fluency overall
- usually people with this have difficulty with conjunctions and prepositions.
- wernickes area - in the left temporal lobe and is responsible for language understanding
- damage to it causes wernickes aphasia - people usually start to produce nonsense words such as neologisms
- wernickes area is for people who have no problem producing language but difficulty understanding it
localisation and function of the brain
- evaluation
- evidence from neurosurgery
- behavious associated with serious mental disorders may be localised , neurosurgery is usually a last resort to treat mental disorders as they target specific areas of the brain, there is a surgery known as cingulotomoy which isolates a region known as the cingulate gyrus which has implications in OCD
- a report was made by darius doughtery who assessed ocd patients post surgery - a follow up after 32 weeks and found 30% of them met a success criteria of a good response to the surgery , 14% with partially good respone
- this shows that behaviours associated with serious disorders can be localised - evidence from brain scans
- studies confirm localisation in everyday behaviours , steven peterson used brain scans to demonstrate how wernickes areas was active during a listening task and brocas area was active during a reading task
- also a review into long term memory by buckner and peterson suggests that semantic and episodic memories subside in different parts of the pre-frontal cortex.
counterpoint : - higher cognitive processes may not be localised and actually use a more holistic distribution
- karl lashley did a study where she removed areas of the cortex (10-50%) of rats brains while they learnt a route through a maze
- it was found that no particular area was more important than another in terms of learning
- shows that the process actually required all parts of the cortex - language localisation questioned
- language may be organised in a more holistic way rather than just broca and wernickes area - a recent review by psychologists show that only 2% of modern researchers believe that language is completely controlled by broca and wernickes area
- there are advancements in imaging techniques such as fMRI scans
- there are various language streams identified across cortex and in the brain regions of the right hemisphere as well as in subcortical regions
hemispheric laterlisation and split- brain research
- knowledge
- localisation - different functions are governed by specific areas
- laterlisation - the brain has 2 hemispheres
left and right hemispheres - language is only controlled by the lh and is known as brocas and wernickes area
- rh produces rudimentry words and is important in emotional context
- lh is an analyser while the rh is a synthesiser
not lateralised functions - vision, motor and somatosensory areas are present in both hemidpheres
- motor is more complex as the brain is cross wired so it is contralateral
- rh controls movement on left hand side of body and lh controls movement on right hand side of body
vision- even more complex as it is contralateral and ipsilateral which means it is opposite and same - sided
- this means that each eye receieves light from the lvf and rvf
- rvf of both eyes connected to the lh and the lvf of both eyes connected to rh
- enables the visual areas to compare slightly different perspectives from each eye and also enables depth - perception
hemispheric laterlisation and split- brain research
- evaluation
- laterlisation in connected brain:
- has been found that hemispheric laterlisation is a feature in both connected brain and split brain
- a study was done by gereon fink et al who used pet scans to analysed active brain areas / regions during a visual processing task
- found that when people were asked to focus on more global elements of an image the regions of the rh were more active
- when they were asked to focus on more finer details specific areas of lh were more dominant - one brain :
- research suggests that people do not have a dominant side of the brain which creates different personalities
- the notion of right and left brained people is wrong
- idea of lh as analyser and rh as synthsiser is also wrong
- study was done by neilson who analysed brain scans of 1000 people from ages of 7-29
- found that they used specific areas for certain tasks so laterlisation is shown but no side was more dominant - laterlisation vs plasticity :
- laterlisation is adaptive as it allows two tasks to be done at the same time with greater efficiency
- lesley rogers - lateralised chickens could hunt for food while also watching for predators but normal chickens couldnt
- neural plasticity is also adaptive as functions can als be over taken by non specialised areas in the opposite hemisphere in cases of damage such as language switching over.
hemispheric laterlisation and split brain - research
- knowledge
- sperry procedure - 11 ppts who had split brain operation were analysed in special set up
- an image of an object would be projected to ppts lvf and processed by rh or projected to rvf and processed by lh
- a normal brain would immediately share this information between the hemispheres
- in split brain this is not possible as the info cannot be conveyed between hemispheres
findings :
- if an image was projected to their rvf and processed by lh they could describe it but if it was projected to lvf and processed by rh they reported nothing was there
- this is because the rh cannot relay messages to the language centres of the lh
- also was found that they could match connecting objects out of sight with their left hand (rh) or select the object most closely associated
- if a pinup picture was projected to their lvf they had a more emotional response like a giggle but most reported that there was nothing or a flash of light
- shows that certain functions in the brain are lateralised and lh is verbal and rh is silent but emotional
hemispheric laterlisation and split brain research
- evaluation
- research support - support of the idea that sperry suggested their is a left brain and right brain which are distinct
- michael cazzinga showed split brain patients performed better at a task than connected controls
- they were more quickly able to identify an odd object amongst similar ones
- this is because in a normal brain the lh is interrupted by the inferior rh - ethics :
- the operation was not done for the purpose of research and so the ppts were not deliberately harmed
- they gave full informed consent as it was volunatry and procedure / experiment was fully explain to them
- however the traume of the operations may have meant they didnt full understand what they were agreeing to
- they were subject to repeated testing over years which may be stressful and have negavtive consequneces on the ppts involvement in task - generalisation issues :
- hard to establish casual relationships
- sperrys split brain patients were compared to neurotypical control group
- this control gorup - none of them had epilepsy - confounding variable
- this means his results may be due to epilepsy rather than split brain
brain plasticity and functional recovery after trauma
- knowledge
brain plasticity :
- idea that the brain can continue to change and develop throughout life
- during infancy our brains experience a rapid growth in synaptic connections
- we gain around 15,000 by the age of 2-3 which is twice as much as an adult
- as we age our rarely used connections are deleted and our frequently used connections are strengthened - synaptic pruning
- this enables life long plasticity and the formation of new neural connections when the brain demands it
research into plasticity :
- eleanor maguire - studied london taxi drivers brains - found a significantly more volume of grey matter in their posterior hippocampus than a matched control group
- this part of the brain is associated with development of navigational and spatial skills
- to be able to become a ldn taxi driver they need to take a complex test known as the knowledge which assess’ their recall of city streets and possible routes
- findings - this new learning experience had altered the brain of the taxi drivers and the ones who had been in the job longer had a more pronounced structural difference - positive correlation
- draganski - imaged brains of medical students 3 months prior and after their exams and noticed learning induced changes in their posterior hippocampus and their parietal cortex.
plasticity of the brain and functional recovery after trauma
- evaluation
- negative plasticity :
- negative behavioural consequences
- brains adapation to prolonged drug use leads to poorer cognitive functions during later life and increased risk of dementia
- 40-60% of amputees develop phantom limb loss
- this is where they experience extreme sensations in the missing limb - unpleasant and painful
- this is thought to be due to the cortical reorganisation in the somatosensory cortex due to limb loss
- suggests the brains ability to adapt to damage is not always beneficial - age and plasticity :
- plasticity reduces with age but can be life long
- ladina bezzola - demonstarted how 40 hours of golf traning chnaged the neural represenation of movement in ppts aged 40-60
- found increased motor cortex ability in the novice golfers compared to control group - found using fMRI scans - more efficient neural representation after training - seasonal changes
- seasonal plasticity occurs in response to changes in the environment such as day length
- scn - controls and regulates the sleep wake cycle
- this part of the brain structure shrinks in all animals during the spring and expands during autumn
- enables ability to adapt to seasonal changes
functional recovery of the brain
- knowledge
- after trauma - unaffected areas of the brain are able to adapt and compensate for the damaged area
- it is an example of neural plasticity
- healthy parts of the brain can take over the functions of the damaged, or missing areas
- can recover quickly after trauma, spontaneous recovery but after a period of time this slows down over weeks and months
- individuals may require more further rehabilitative therapy to recover
what happens in the brain during recovery ? :
- brain rewires and reorgansises itself by forming new synaptic connections close to where damage was done
- the secondary neural pathways which are not used are activated to continue functioning usually in the same way as before.
changes in strcuture of brain :
- axonal sprouting - when new nerve endings are formed and connect with other undamaged nerve cells to create new neural pathways
- denervation supersensitivity - when axons with similar functions become aroused to higher levels to compensate for the lost ones, but this can result in oversensitivity to certain messages like pain
- recruitment of homologous areas in opposite sides of the brain
- this is so specific tasks can still be performed
- for example if brocas area was damaged in lh the equivalent in the rh would carry out its functions and after a while the functionality will shift back to the left side
functional recovery of the brain
- evaluation
- research support
- understanding the processess involved in plasticity has aided the field of neurorehabilitation
- axonal sprouting - encourages new therapies to be tried
- such as constraint induced therapy for stroke patients which is repeatedly used practiced using affected body part while unaffected part is restrained - cognitive reserve
- level of education may have an impact on recovery
- schneider found that those who had a brain injury but spent more time in education had higher chances of dfr ( disability free recovery )
- 40% of patients with dfr has 16+ years in education whereas only 10% had less than 12 years
Ways of studying the brain - fMRI
- knowledge
- fMRI - detects changes in blood oxygenation and flow as a result of neural activity in the brain
- when the brain becomes more active it consumes more oxygen and so the blood flow is directed to the active area to meet the increased demands known as a hemodynamic response
- produces 3 dimensional images known as activation maps and shows the specific parts of the brain which are involved in particular mental processes
- implications in understanding localisation of function
Ways of studying the brain - EEG
- Knowledge
- measures electrical activity within the brain via electrodes which are fixed to a patient skull using a skull cap
- shows brain wave patterns which are generated from the action of thousands of neurons
- shows overall brain activity
- often used by clinicans as a diagnostic tool - for example unusual arythmic patterns may lead to neurological abnormalities
Ways of studying the brain - ERP
- knowledge
- types of brainwaves which are triggered by particular events
- isolates the neural response associated with particular sensory, cognitive and motor events
- filters out the extraneous brain activity from the original EEG recordings which leaves ERP.
Ways of studying the brain - post mortems
- knowledge
- analyses of a persons brain following their death
- likely to be someone with a rare disorder or someone who experienced unusual deficits in their cognitive processes and behaviours growing up
- helps to establish the cause of affliction the person experienced
- compared with a neurotypical brain to ascertain the extent of the differences
Ways of studying the brain - fMRI
- evaluation
strengths :
- does not rely on the use of radiation and if it is administered correctly it is risk - free, straightforward and non - invasive
- produces high spatial resolution images - depicts detail by the millimeter
- shoes clear images of how brain activity is localised
weaknesses :
- more expensive than other neuroimaging techniques
- poor temporal resolution, there is a 5 second time lag between the picture being displayed on screen and the initial firing of the neural activity
Ways of studying the brain - EEG
- evaluation
strengths :
- useful in studying stages of sleep and the diagnosis of disorders
- for example epilepsy is chatacerised by random outburst of activity which can be easily seen on screen
- produces high temporal resolution images
- accurate brain activity with resolution of millisecond or less
weaknesses :
- generalised nature of the information received from the thousands of neurons
- hard to pin point the exact source of neural activity
- doesn’t allow researchers to distinguish the difference between activities originating in different but adjacent locations
Ways of studying the brain - ERP
- evaluation
strengths :
-specificity in measurement of neural processes
- high temporal resolution which is much better than other neuroimaging techniques like fMRI because the data is derived from EEG
- measures cognitive functions and deficits such as maintenance of working memory
weaknesses :
- other extraneous variables such as noise which have to be completely eliminated in order for data to be pure
- lack of standardization between cases so its difficult to confirm findings
Ways of studying the brain - post mortems
- evaluation
strengths :
- vital in providing foundation of early understanding of brain processes
- broca and wernicke’s area actually used post - mortems to help establish the link between language, behaviour and the brain
- case of HM for example - allowed us to identify areas of damage and his memory deficits
weaknesses :
- causation - images observed may not be due to brain deficits but also other problems such as trauma or decay
- ethical issues - people cannot give informed consent to this
Biological Rhythms
- Circadian - Bio Rhythms
- biological rhythms :
all humans are subject to biological rhythms - they are important on exerting influence on how our body system behaves
- governed by 2 things :
1. internal biological clock - endogenous pacemaker
2. external changes in environment - exogenous zeitgeber
frequency of occurrence :
- multiple times during the day - circadian rhythm
- longer than 24 hrs - infradian rhythm
- even longer - circulluan rhythm
- circadian rhythm’s last around 24 hrs
Biological Rhythms
- Circadian - Sleep / Wake cycle
- change in alertness demonstrates the affect of daylight ( exogenous zeitgeber )
- also can be affected by endogenous pacemaker ( scn )
-scn is located directly above the optic chaism and provides the eye information about light - exogenous zeitgebers can reset scn.
Biological Rhythms
- Circadian - Siffre’s study
- Siffre wanted to study the affect on his own biological rhythm
- He went into a cave for 2 months and did not have access to any natural source of light or sound but he had adequate food
-resurfaced in mid september after being there for around 2 months - \ decade later this was tested again where a man went into a texan cave for 6 months
- in both cases the free running internal body clock settled down to just above 24 hours which suggests
- continued to sleep and wake on bio rhythm