Bleeding in Pregnancy Flashcards

(63 cards)

1
Q

what are the 3 trimesters of pregnancy cut of

A

1st Trimester –completes @ 12 weeks
2nd trimester – completes @ 28 weeks
3rd trimester – completes @ 40 weeks

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2
Q

what is bleeding in early pregnancy defined as

A

bleeding in 1st trimester

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3
Q

what is the marker looked for in a pregnancy test

A

hCG

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4
Q

what can cause bleeding in early pregnancy

A

Implantation bleeding

Chorionic haematoma

Cervical causes:
- Infection, Malignancy, Polyp

Vaginal causes:
- Infection, Malignancy (rare)

Unrelated : Haematuria, PR bleeding etc.

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5
Q

bleeding in early pregnancy is very rare - true or false

A

false

- common problem, seen in about 20%

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6
Q

what are Sx of a miscarriage

A

Postive UPT
Varied gestation
Bleeding (MORE than cramping)
Period-like cramps

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7
Q

Ix of miscarriage

A

USS
- confirms if pregnancy in situ, process of explosion or empty uterus

Speculum exam
- if os closed (threatened), products are sited at open os (inevitable) or in vagina (complete)

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8
Q

what are the types of miscarriages

A
threatened miscarriage 
inevitable miscarriage
incomplete miscarriage
complete miscarriage 
early fetal demise
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9
Q

what is early fetal demise

A

pregnancy in-situ, no heartbeat

mean sac diameter > 25mm

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10
Q

what is the general meaning of all the types of miscarriage

A

threatened - risk to pregnancy but the pregnancy continues

inevitable - pregnancy can’t be saved

incomplete - part of pregnancy lost already

complete - all of pregnancy lost, uterus is empty

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11
Q

what is ectopic pregnancy

A

implantation out with uterus

  • common site fallopian tube
  • other site; ovary, peritoneum, liver, cervix
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12
Q

presentation of an ectopic pregnancy

A

Pain > bleeding
[pain may seem out of proportion with bleeding]
dizziness/collapse/shoulder tip pain
SOB

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13
Q

what are the findings of ectopic pregnancy

A

Pallor, hemodynamic instability, signs of peritonism, guarding & tenderness.

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14
Q

how is management of ectopic pregnancies decided

A

per presentation

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15
Q

Mx of ectopic pregnancies

A

acutely unwell - surgery

stable, low levels of hCG - medical

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16
Q

what is a molar pregnancy

A

non-viable fertilized egg implants in the uterus and will fail to come to term

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17
Q

what is the appearance of a molar pregnancy

A

Overgrowth of placental tissue with chorionic villi swollen with fluid giving picture of “grape like clusters”.

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18
Q

what are the types of molar pregnancy

A

complete

partial

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19
Q

what is the risk of a complete mole

A

2.5% risk of developing into Choriocarcinoma

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20
Q

what is the features of a complete mole

A

Egg without DNA

1 or 2 sperms fertilise, result in diploidy ( paternal contribution only)

no fetus

overgrowth of placental tissue

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21
Q

what is the features of a partial mole

A

Haploid egg

1 sperm ( reduplicating DNA material) or 2 sperms fertilising egg, result in triploidy

may have fetus

overgrowth of placental tissue

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22
Q

molar pregnancy presentation

A

hyperemesis
Varied bleeding and passage of “grapelike tissue”
Fundus > dates.
Occasional shortness of breath

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23
Q

what can be seen on USS in a molar pregnancy

A

“snow storm appearance” +/- fetus

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24
Q

what is implantation bleeding

A

Fertilised egg when implants into the uterine wall.

Timing is about 10 days post-ovulation

Bleeding is light/brownish and limited > occasionally mistaken as period

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25
Mx of implantation bleeding
watchful waiting
26
what is Chorionic Haematoma
Pooling of blood between endometrium and the embryo due to separation
27
Sx of Chorionic Haematoma
Bleeding, cramping, threatened miscarriage
28
Mx of Chorionic Haematoma
self limiting | resolve eventually
29
what can happen in Chorionic Haematoma if it is a large haematoma
infection, irritability ( causing cramping) and miscarriage
30
what infections in the vagina can cause bleeding in early pregnancy
Trichomoniasis ( strawberry vagina) Bacterial vaginosis Chlamydia
31
what is the definition of bleeding in early pregnancy and bleeding in late pregnancy
early < 24 weeks late > 24 weeks
32
what are causes of antepartum haemorrhage [i.e. bleeding in late pregnancy]
Placenta previa Placental Abruption Local causes – polyps, Cancer, Infection Vasa previa – rare Uterine rupture
33
what is placental abruption
part of the placenta becomes detached from the uterus
34
risk factors for abruption
``` pre-eclampsia/HTN trauma smoking/cocaine/amphetamine renal disease/DM poly-hydramnios multiple pregnancy ```
35
what does a placental abruption cause
post partum haemorrhage DIC Couvelaire uterus fetal/maternal death
36
Sx of placental abruption
painful uterine tenderness/wooden hard uterus feels larger difficult to feel fetal parts
37
how is a diagnosis of placental abruption made
purely clinical | [not ultrasound]
38
what is placenta previa
placenta partially or totally implanted in the lower uterine segment
39
how is placenta previa classified
major (anything over cervix) or minor (anywhere else not covering cervix) on ultrasound
40
Sx of placenta previa
painless, recurrent 3rd trimester bleeding uterus soft non tender Malpresentations – Breech/Transverse/Oblique High head CTG usually normal
41
Ix of placenta previa
ultrasound | [check anomaly scan]
42
Mx of placenta previa
Major degrees of placenta praevia (< 2cm from os /covering os) > C-Section Minor degrees of placenta praevia (>2cm from os)  consider vaginal delivery
43
what is placenta accreta
Placenta invades myometrium
44
what is placenta accreta associated with
severe bleeding | PPH
45
risk factors for placenta accreta
placenta praevia & prior caesarean delivery.
46
what are most uterine ruptures caused by
c-sections
47
what is vasa praevia
blood vessels within the placenta or the umbilical cord that are trapped between the foetus and the opening to the birth canal
48
why is vasa praevia worrying
can cause fetal death due to blood loss
49
what are Sx that would make you think that the cause of APH is local
``` Small volume Painless Provoking factor Uterus soft, non tender No fetal distress ```
50
Tx of placenta praevia
Admit and gain IV access Blood tests/cross match 12mg Betamethasone IM Delivery
51
why are steroids given
promote fetal lung surfactant production | decrease risk of neonatal RDS
52
what steroid is preffered
Betamethasone
53
what drugs can be given to delay delivery of the baby by a short period
tocolysis
54
Tx of vasa praevia
C-Section
55
Tx of placenta accreta
hysterectomy
56
what is definition of post partum haemorrhage
the loss of more than 500 ml of blood within the first 24 hours following childbirth
57
what are complications of PPH
``` Maternal fatigue feeding difficulties prolonged hospital stay delayed lactation pituitary infarction transfusion haemorrhagic shock DIC death ```
58
what is the definition of secondary post partum haemorrhage
blood loss of >500ml more than 24hours after childbirth and before 6 weeks
59
how is PPH classified
Minor PPH <500ml Moderate PPH 500 - 1500ml Major PPH = >1500ml
60
what is the 4 T's that cause PPH
Tone Trauma Tissue Thrombin
61
what are risk factors for PPH
``` anaemia previous c-section placenta praevia, accreta previous PPH or retained placenta Multiple pregnancy ``` prolonged labour retained placenta
62
Initial Mx of PPH
Uterine massage 5 units iv Syntocinon stat 40 units Syntocinon in 500ml Hartmanns - 125 ml/h
63
Mx of persistent PPH
Urinary Catheter 500 micrograms Ergometrine IV Non-surgery - packs&balloons, factor VIIa, arterial embolisation Surgery - uterine artery ligation, hysterectomy