Block 11 - Week 2

Question 1

Desogestrel
Etonogestrel
Levonogestrel

Answer 1

Progesterone nuclear hormone receptor agonist

Female contraceptives - oral contraceptive pill in combo with oestrogen or high dose levonorgestrel for emergency contraception

Bind to receptors and slow frequency of release of GnRH from hypothalamus and blunt preovultory LH surge and maintain high levels of progesterone

Question 2

Paracetamol

Answer 2

Analgesic and antipyretic compound - COX inhibitor

Used when NSAIDS can’t be used I.e patient with peptic ulcer

Question 3

Oxytocin

Answer 3

Hormone to induce labour - GPC agonist

Used to stimulate contraction of uterine smooth muscle - delivery and post
Partum

Has receptors which once activated increase intracellular ca2+ Which activate myosin’s light chain kinase causing muscle contraction

Question 4

Ethinylestradiol

Oestradiol

Answer 4

Interact with oestrogen receptor on female organs , hypothalamus and pituitary gland and regulates gene transcription In nucleus leading to an incr in SHBG (sex hormone binding globulin ) , TBG from anterior pituitary

Oestrogen nuclear hormone receptor agonist

Question 5

Dinoprostone

Answer 5

Prostaglandin E2 receptor agonist

Direct myometrial stimulation - used in labour - induce cervical ripening and used as a vaginal suppository

Question 6

Flucloxacillin

Answer 6

Broad spectrum antibiotic

Pencillin beta lactam antibiotic - transpeptidase inhibitor - inhibitor of cell wall synthesis causing cell lysis

Bacterial infections caused by staphylococcus aureus