Block 2 Lecture 6 -- ASDs Part 2 Flashcards Preview

PHS 931 > Block 2 Lecture 6 -- ASDs Part 2 > Flashcards

Flashcards in Block 2 Lecture 6 -- ASDs Part 2 Deck (15)
Loading flashcards...
1
Q

Tiagabine MoA

A

GAT-1 inhibitor

2
Q

Tiagabine indication

A

focal (mainly adjunct)

3
Q

Where are GABA Reuptake Transporters located?

A

presynaptic and astrocytic membranes

4
Q

Vigabatrin MoA

A

GABA-TA inhibitor

5
Q

Vigabatrin indication

A

1) refractory complex focal
2) West
3) adjunct for infantile spams

6
Q

What is West syndrome?

A

spasms beginning between 3-5 mos; non-treatable

– mental retardation

7
Q

Phenobarb MoA:

A

binds barb site of GABAa to prolong opening of Cl chanel

8
Q

Phenobarb indication

A

all seizure types except absence

9
Q

BZD indication

A

all including status epilepticus

10
Q

What BZDs are used for epilepsy?

A

1) diazepam
2) clonazepam
3) lorazepam
4) chlorazepate
5) clobazam

11
Q

Where is diazepam mainly used?

A

SE

12
Q

Where is clonazepam mainly used?

A

long-term (also absence)

13
Q

Where is lorazepam mainly used?

A

SE

14
Q

Where is chlorazepate mainly used?

A

in long-term

15
Q

Where is clobazam mainly used?

A

adjunct for Lennox-Gastaut syndrome