Blood coagulation Flashcards Preview

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Flashcards in Blood coagulation Deck (5)
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1
Q

Aspirin

A
  • prevent formation of throxane in platelets
  • action of aspirin on platelet is permanent
2
Q

Heparin

A
  • binds to thrombin (inactivates) and antithrombin III (activates)
  • low mw heparins bind only to antithrombin III
3
Q

Warfarin

A
  • blocks epoxide reductase in liver and prevents the regeneration of active form of Vit. K.
4
Q

Streptokinase

A
  • thrombolytics agent
  • plasminogen activator
  • converts plasminogen to plasmin enabling the dissolution of clots
5
Q

Clopidogrel

A
  • irreversibly inhibits P2Y12-R in platelets