DNA replication Flashcards by Minh Lam

Q

Etoposide

A

Topoisomerase II (Eukaryotic)

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Q

Camptothecin

A

Topoisomerase I (Eukaryotic)

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Q

Topotecan

A

Topoisomerase I (Eukaryotic)

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Q

Actinomycin D

A

Phenoxazone ring intercalates b/w C & G; Prevents formation of regions of ssDNA;
Rx: Wilm Tumor (kidney), Kaposi Sarcoma; Testicular cancer

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Q

Quinolones & Fluoroquinolonesr

A

Inhibits Gyrase activity by preventing re-ligation of DNA strands

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