Blood glucose levels and obesity Flashcards

(42 cards)

1
Q

What does chronic elevation of blood glucose levels lead to

A

endothelium cells taking in more glucose than normal leading to atherosclerosis damaging the blood levels

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2
Q

What can damaged blood vessels from atherosclerosis lead to

A

cardiovascular disease
stroke
peripheral vascular disease

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3
Q

What can the small blood vessels being damaged by elevated glucose levels result in

A

haemorrhage (serious bleeding of blood vessels in the retina)
renal (kidney) failure
peripheral nerve dysfunction

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4
Q

What are hormones released from

A

one of the endocrine glands

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5
Q

What do hormones travel through

A

blood stream to a target tissue

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6
Q

What does a hormones target tissue have

A

cells with receptors for hormones so only some tissue are affected by specific hormones

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7
Q

What endocrine gland monitors the blood glucose concentration

A

pancreas

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8
Q

What responds to changes in blood glucose concentration

A

pancreatic receptors

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9
Q

Insulin and glucagon act antagonistically what does that means

A

have the opposite effect on the same organ

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10
Q

What happens when blood glucose levels increase

A

pancreatic receptors respond by increasing secretion of insulin from the pancreas
insulin travels to the liver in the blood
insulin activates the conversion of glucose to glycogen in the liver decreasing blood glucose concentration

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11
Q

What happens when the is low blood glucose levels

A

pancreatic receptors respond by increasing secretion of glucagon from the pancreas
glucagon activates the conversion of glycogen to glucose in the liver increasing blood glucose concentration

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12
Q

What happens during exercise and fight or flight responses

A

glucose levels are raised by adrenaline released from the adrenal glands stimulating glucagon secretion and inhibiting insulin secretion

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13
Q

What happens once an emergency is over

A

insulin brings the blood glucose concentration back down to normal

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14
Q

What is the regulation of blood glucose levels an example of

A

negative feedback control

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15
Q

When does type 1 diabetes usually occur

A

in early childhood

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16
Q

What wrong with a person with type 1 diabetes

A

unable to produce insulin

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17
Q

What is type 1 diabetes treated with

A

regular injections of insulin

18
Q

When does type 2 diabetes develop

A

typically later in life

19
Q

What is the likelihood of developing type 2 diabetes increased by

A

being overweight

20
Q

Whats wrong with people with type 2 diabetes

A

individuals produce insulin but receptors on liver cells are less sensitive to it

21
Q

What is the insulin resistance in type 2 diabetes linked to

A

a decrease in the number of insulin receptors in the liver leading to failure to convert glucose to glycogen

22
Q

What is type 2 diabetes treated by

A

lifestyle changes- weight loss/exercise/dietary changes

23
Q

How is blood glucose level monitored by the body

A

pancreatic receptors

24
Q

What indicates diabetes

A

glucose present in urine

25
What si used to diagnose diabetes
glucose tolerance test
26
Describe the glucose tolerance test
the blood glucose concentrations of the individual are initially measured after fasting the individual then drinks a glucose solution and changes in their blood glucose concentration are measured for at least the next two hours
27
Compare non diabetic and diabetic in a glucose tolerance test
the blood glucose concentration of a diabetic usually starts at a higher level than that of a non diabetic diabetics blood glucose concentrations increase to a much higher level than that of a non diabetic and takes longer to return to its starting concentration
28
Why do patients have to fast before taking a glucose tolerance test
to ensure any glucose present in the patients blood os form the glucose drink they have been given
29
the patient had eaten before taking the test their glucose levels would be higher due to
the food they had eaten and not necessarily due to a lack of insulin
30
What is obesity
obesity is characterised by excess body fat in relation to lean body tissue
31
What is BM1
body max index
32
What is an advantage to BMI
extremely easy to calculate
33
What is a disadvantage to BMI
BMI can wrongfully classify individuals as obese
34
What BMI value indicates obesity
over 30
35
What are the main causes of obesity
high fats diets and not enough physical activity
36
What is obesity linked to
high fats diets and a decrease in physical activity
37
What does exercise do
increases energy expenditure and preserves lean tissue
38
What can exercising help reduce risk factors for CVD by doing
keeping weight under control minimising stress reducing hypertension improve HDL blood lipid profiles
39
What should the energy intake in the diet do
limit fats and free sugars
40
How do you calculate BMI
Weight(kg)/height squared
41
What happens to individuals in both types of diabetes
Blood glucose levels will rise rapidly after a meal The kidney will remove some of this glucose resulting in glucose appearing in the urine
42
What is obesity a major risk factor for
type 2 diabetes cardiovascular disease