Blood Group Flashcards
(24 cards)
The first to give IV infusions is
Boyle
Who discovered the ABO system
Karl Landsteiner in 1901
First anti-coagulant
Na citrate
First human blood transfusion
Agote in 1914
What can stimulate an immune response(antibody) in the body
Antigen
Antibodies are produced by
B lymphocytes
The ABO system is regulated by what chromosome
9
Blood grouping is based on
Red cell antigen
Blood group can be objectively determined at what age
> 2years
Silent gene or amorphs is for what blood group
O
Rhesus factors has what antigens
D antigen
d is an amorph
Almost all persons greater than 6/12 have what serums
Anti-A or Anti-B corresponding to which antigen is present or lacking
The human blood is grouped into how many ABO phenotypes
6 main
The ABO has how many antigens?
4 antigens
A1, A2, B, H
About 80% of the population have what antigen present in various body secretions.
A and B
O cells possess what antigen
Precursor H antigen
H gene is present in all red cell groups except what type
Bombay red cells
ABH antigens have what similar characteristics
Same 15 amino acids protein backbone
Same 4 sugar side-chain
Specificity of the ABH antigen is determined by
Terminal sugars
ABH antigens are also referred to as
Lewis substance
The terminal sugars for
H antigen of group O?
Group A?
Group B?
L-fucose
L-fucose and galnac( N-acetyl galactosamine).
L-fucose and D-galactose
Weak form of RhD antigen is
D^u
How many genes controls rhesus
3 genes
Causes of Hemolytic Disease of the Newborn include
Rhesus
Kell
Duffy
Kidd
