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Physiology > Blood Groups > Flashcards

Blood Groups Flashcards

1
Q

Discovery of blood groups

A

Karl landsteiner

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2
Q

Antigen or agglutinogens are seen in

A

RBC

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3
Q

Antibody or agglutinins found in

A

Plasma

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4
Q

Cause of clumping of blood

A

Particular antigen and corresponding antibody if together causes clumping

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5
Q

Landsteiners law

A

1,if antigen is present ,then antibody absent in serum
2,if antigen is absent,then antibody present in serum
(NA to rh factor)

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6
Q

Type of blood used in blood transfusion

A

Compatible blood

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7
Q

The method of reaction

A

Antigen of the donor+antibody of recipient

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8
Q

O group no agglutination.why?

A

No antigen

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9
Q

AB group cause agglutination due to

A

Absence antibody

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10
Q

Cross matching

A

*serum of recipient+donor RBC
*if agglutinationnof RBC occurs,blood is not used

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11
Q

Is rh factor an antigen or antibody

A

Antigen

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12
Q

Which rh antigen is more antigenic

A

D antigen
With d -rh +ve
Without-d rh-ve

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13
Q

Among Asians how much are 85%and15% rh

A

+ve 85%
-ve 15%

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14
Q

No natural antibody for D antigen. Comment

A

Rh-ve and rh +ve blood, anti D forms
Rh+ve and rh-ve blood, no risk

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15
Q

ABO incompatibility

A

Rh -ve and Rh+ve blood first not much effect
*delayed transfusion results in agglutinin
*2nd time when receiving rh+ve ,severe transfusion occurs

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16
Q

Erythroblastosis fetalis

A

*Rh -ve mother and Rh+ve child
*no passage of rh antigen through placental barrier
*after postpartum, 1 month antibody is formed
2nd time,rh+ve child,antibody leaks through placenta
*rh antigen can’t pass but 4h agglutinin can
*rh agglutinin cause he hemolysis and agglutination of fetal RBC s
*severe hemolysis cause jaundice
*rapid release of RBCs from spleen and liver other bone arrow at proerythroblastic stage are released
*excess hemolysis,anemia occurs and infant dies

17
Q

Erythroblastosis fetalis

A

*Rh -ve mother and Rh+ve child
*no passage of rh antigen through placental barrier
*after postpartum, 1 month antibody is formed
2nd time,rh+ve child,antibody leaks through placenta
*rh antigen can’t pass but 4h agglutinin can
*rh agglutinin cause he hemolysis and agglutination of fetal RBC s
*severe hemolysis cause jaundice
*rapid release of RBCs from spleen and liver other bone arrow at proerythroblastic stage are released
*excess hemolysis,anemia occurs and infant dies

18
Q

Prevention of arythroblastosis fetalis

A

Physiology (7 decks)

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