Blood Products

Question 1

Packed red cells

• constituents
• uses

Answer 1

RBC

Acute blood loss
Chronic/symptomatic anemia

RBCs - non ACS
Transfuse if - U70
Target of - 70-90g

RBCs - ACS
Transfuse if U80
Target of 80-100g

Question 2

FFP

• constituents
• uses

Differences between FFP and cryoprecipitate

Answer 2

FFP - Clotting factors

DIC
Hemorrhage 2ndary to liver disease
All major bleeds
FFP
Transfuse if - abnormal coag time and bleeding

Cryoprecipitate - conc fibrinogen, F8, vWF

• DIC and low fibrinogen
• vW disease
• major bleeds

Question 3

Platelets

• constituents
• uses

Answer 3

Platelets

Platelets
Transfuse if U100 AND bleeding from critical sites
Transfuse if U30 AND bleeding without hemodynamic instability

Question 4

Guidelines when transfusing RBCs

Answer 4

RBCs - non ACS
Transfuse if - U70
Target of - 70-90g

RBCs - ACS
Transfuse if U80
Target of 80-100g

Platelets
Transfuse if U100 AND bleeding from critical sites
Transfuse if U30 AND bleeding without hemodynamic instability

FFP
Transfuse if - abnormal coag time and bleeding