Blood Products Flashcards
(25 cards)
what is the shelf life of PRBC?
42 days
1 unit of PRBC increases Hct by what?
3-4%
7 ml/kg will increase Hct by what?
10%
1 ml PRBC/kg will increase Hct by what?
1%
in a bleeding patient what do you want to keep the platelet count above?
50,000
one unit of platelets will increase platelet count by what?
10,000
what are apheresis platelets?
collected from a single donor
what is in 1 unit of FFP?
the plasma from 1 unit of whole blood
what are some indications for FFP?
single coagulation factor deficiency
warfarin effect
DIC
cryoprecipitate is valuable because it contains what?
fibrinogen
what fibrinogen levels require cryoprecipitate?
< 100 mg/dl
1 unit of cryoprecipitate will increase fibrinogen by what?
25 mg/100 ml
one unit of cryoprecipitate per 10 kg body weight raises fibrinogen by what?
50 mg/dl
what are the three types of complications from blood transfusions?
transfusion related complications
metabolic complications
infectious complications
what is acute hemolytic transfusion reaction (AHTR)?
when ABO incompatible blood is transfused, it results in RBC lysis and release of bradykinin and histamine
what are signs and symptoms of AHTR in an anesthetized patient?
fever
hypotension
hemoglobinurea
what are signs and symptoms of AHTR in an awake patient?
fever
nausea
chest pain
flank pain
how do you treat AHTR?
stop transfusion
send donor unit to blood bank
treat hypotension with fluids and vasopressors
monitor for DIC
what is delayed hemolytic transfusion reaction?
extravascular hemolysis that occurs 2 days to months after transfusion
what is the most common transfusion reaction?
febrile nonhemolytic transfusion reaction (FNHTR)
FNHTR is most common with what blood product?
platelets
what is TRALI?
severe pulmonary insufficiency following blood product transfusion
what happens to potassium levels with transfusion?
hyperkalemia because PRBC storage causes leakage of potassium
what happens to calcium levels with transfusion?
citrate binds to the calcium leading to hypocalcemia
