BLOOD REVIEW

Question 1

Note anemia leads to reticulocytosis (large cells which can increase MCV) - but need iron stores to be available

Answer 1

lit

Question 2

Hypochromic RBC seen in

Answer 2

HG sythesis problem - iron deficiency, thalassemia

Question 3

Where is most iron absorbed

Answer 3

Duodenum

Question 4

Whats haptoglobin

Answer 4

Binds to free Hemoglobin

Question 5

What test for SLE

Answer 5

Coombs Test

Question 6

Sickle Cell anemia vascular problem

Answer 6

Microvascular occlusions ‘sticky’

Question 7

How does beta thalassemia lead to Hepatosplenomegaly

Answer 7

alpha globin chain aggregate, ppt, apoptosis, anemia, Extramedullary Hematopoiesis

Question 8

Whats erythroblastosis fetalis

Answer 8

Maternal AB on fetal RBC

Question 9

Megaloblastic

Answer 9

DNA synthesis problem - Folic Acid, B12 deficiency

Question 10

How does chronic alcohol intake lead to cytopenia

Answer 10

Cirrhosis, Splenomegaly, then cytopenias

Question 11

Microcytic

Answer 11

Iron deficiency; Thalessemia

Also chronic blood loss wo iron replacement - Period

Question 12

What is aspirin for

Answer 12

Antiplatelet effect

Question 13

Heparin side effects

Answer 13

Thrombosis (IgG complexes trigger coagulation)

Osteoporosis