Blood transfusion Flashcards
(22 cards)
what blood group can receive all blood
AB
what blood group can donate all
O
what happens if RH -ve exposed to +ve D protein
intravascular haemolysis
group and save blood screen looks at
ABO
Rh
antibody screen
emergency blood uses
O -ve
what is a washed red cell concentrate
removes all traces of plasma proteins to prevent urticarial or anaphylactic reactions
packed platelets used in
bleeding patient with severe thrombocytopenia or prophylactically in marrow failure
what is the risk of giving platelets
most likely to cause sepsis from bacterial infection
what is a granulocyte concentrate used
in severe neutropenia with evidence of bacterial infection
when is fresh frozen plasma used
acquired coagulation factor deficiency
what does fresh frozen plasma contain
all coagulation factors
what is cryoprecipitate used in
DIC
alloimmunisation =
delayed transfusion reaction to foreign antigens on donors blood destroying transfused cells (mainly clinically silent)
haemolytic transfusion reaction =
immediate ABO reaction via complement alternative pathway
when does haemolytic transfusion reaction happen
immediately -within minutes
symptoms of haemolytic transfusion reaction
rigors/ fever lumbar pain dyspnoea hypotension haemoglobinuria renal failure
what serious complication does haemolytic transfusion reaction result in
disseminated intravascular coagulation
treatment of haemolytic transfusion reaction
ionotrophics and cessation of transfusion
non-haemolytic transfusion reaction
febrile reactions due to presence of leucocyte Ig against donor leucocytes
symptoms of non-haemolytic transfusion reaction
pyrexia
tachycardia
chills
rigor
post-transfusion purpura=
severe bleeding 7-10 days after transfusion containing platelets
anaphylaxis with hypotension, dyspnoea, wheezing and stridor or angioedema from transfusion treat with –>
stopping transfusion
give adrenaline
give chlorphenamine
bronchodilators and steroids
