Haematology basics

Question 1

myeloid cells=

Answer 1

all blood cells except lymphocytes

RBC, platelets, granulocytes

Question 2

RBC lifespan

Answer 2

120 days

Question 3

haemaglobin made up of

Answer 3

2 alpha and 2 beta polupeptide chains and a haem molecule

Question 4

how does o2 bind to haemaglobin

Answer 4

ferrous atom in the haem molecule

Question 5

how does binding of 1 oxygen molecule change Hb

Answer 5

change in configuration to oxyHb which has a higher affinity for O2

Question 6

3 other factors affecting O2 binding to Hb

Answer 6

H+
CO2
2-3BG

Question 7

platelet lifespan =

Answer 7

7 days

Question 8

granulocytes life span

Answer 8

7 hours

Question 9

Hb=

Answer 9

concentration of Hb in blood

Question 10

red cell distribution width elevation suggests

Answer 10

variation in red cell size and shape

Question 11

haematocrit =

Answer 11

vol percentage of RBCs in blood

Question 12

raised haemtocrit suggests

Answer 12

polycythemia

Question 13

reduced haemtocrit suggests

Answer 13

anaemia

Question 14

reduction in reticulocyte count with anaemia suggests

Answer 14

bone marrow failure

Question 15

raised reticulocyte count suggests

Answer 15

reaction haemorrhage or haemolysis

Question 16

c-reactive protein=

Answer 16

acute phase protein