Body Fluid Compartments Flashcards Preview

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Flashcards in Body Fluid Compartments Deck (15):
1

Water always moves from ____ osmolality to ____osmolality

low, high

2

What is normal Sodium plasma

140

3

What is normal ICF potassium

150

4

What is normal Clhoride plasma

102

5

What is normal bicarbonate plasma

24

6

What is normal protein ICF

130

7

How is the difference between ICF and ECF generated is they have the same osmolality?

Cells have a negative charge because of 1. sodium-potassium ATPase (cell is more permeable to K than Na and resting membrane potential is close to K equilibrium potential) 2. "Fixed" intracellular polyanions - organic phosphates and proteins, 3. Multiple ion channels

8

What happens on a salt only diet?

the cells shrink as water moves out to less the osmolarity

9

What happens if we drink water alone?

lowers ECF sodium concentratiuon and osmolality, both ECF and ICF volume increases, until you pee it out, inhibiion of vasopression also happens

10

What is hypoatremia

it is when salt is ECF is low and water in ICF is high

11

What is hypernatremia

it is when salt is ECF is high and the water in ICF is low

12

what is oncotic pressure?

it is an osmotic force due to charged proteins mainly albumins

13

How do you measure fluid movement across capillaries?

Fluid flux = permeability x (hydrostatic pressure gradient - oncotic pressure gradient)

14

Why does edema happen

It is increased ISF volume:
Increased capillary hydrostatic pressure (heart failure)
Decreased plasma albumin concentration (liver failure)
Increased capillary permeability (allergy, trauma)
Lymphatic obstruction

15

the plasma vs interstitial depends on balance of

oncotic and hydrostatic pressure