Boncher Exam 1 Flashcards

(59 cards)

1
Q

penicillin binding protein AKA

A

transpeptidase

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2
Q

penicillins come from

A

6-aminopenicillanic acid

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3
Q

natural penicllins

A

Pen G and Pen V

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4
Q

natural penicllin spectrum

A

Gram + cocci
Gram + bacilli
Gram - cocci (not bacilli)
Spirochetes

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5
Q

Anti-Staphylococcal Penicillins

A

Naficillin, Oxacillin, Dicloxacillin, Cloxacillin

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6
Q

Anti-Staphylococcoal spectrum

A

Staph, not MRSA

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7
Q

Pen G route

A

parenteral

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8
Q

Pen V route

A

oral

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9
Q

to target MRSA

A

vancomycin

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10
Q

aminopenicillins

A

“smart penicillins”

ampicillin and amoxacillin

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11
Q

aminopenicillin spectrum

A

streptococci and enterococci

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12
Q

aminopenicillin AE

A

diarrhea

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13
Q

amoxacillin brand

A

Amoxil

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14
Q

amoxacillin + clavulanate

A

Augmentin

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15
Q

ampicillin brand

A

Ampi, Omnipen

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16
Q

ampicillin + sulbactam

A

Unasyn

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17
Q

green pus means

A

pseudomonas infection

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18
Q

anti-pseudomonals

A

piperacillin, ticarcillin, azlocillin, mezlocillin, carbenacillin

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19
Q

piperacillin brand

A

Pipracil

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20
Q

piperacillin + tazobactam

A

Zosyn

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21
Q

Ticarcillin + clavulanic acid

A

Timentin

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22
Q

anti-pseudomonal spectrum

A

pseudomonas, streptococci, enterococci, enteric Gram -

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23
Q

cycloserine MOA

A

prevent addition of terminal D-Ala, D-Ala

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24
Q

vancomycin MOA

A

inhibit enzyme for glycosylation

25
bacitracin MOA
inhibit BPP
26
bactericidal drugs
penicillins, cephalosporins, aminoglycosides, vancomycin, fluoroquinolones, metronidazole
27
ampicillin absorption
poor
28
amoxicillin absorption
complete
29
cephalosporins based on
7-aminocephalosporanic acid (7-ACA)
30
cephalosporin MOA
inhibit PBP
31
cephalosporins don't cover
enterococci, C. diff, Listeria
32
cefadroxil brand and generation
Duricef, 1st gen
33
cephalexin brand and generation
Keflex, 1st gen
34
Cefazolin brand and generation
Kefzol, 1st gen
35
cefaclor brand and generation
Ceclor, 2nd gen
36
cefprozil brand and generation
Cefzil, 2nd gen
37
cefuroxime brand and generation
Ceftin, 2nd gen
38
cefoxitin generation
2nd gen
39
cefdinir brand and generation
Omnicef, 3rd gen
40
cefixime brand and generation
Suprax, 3rd gen
41
cefditoren brand and generation
Spectracef, 3rd gen
42
ceftibuten brand and generation
Cedax, 3rd gen
43
cefpodoxime brand and generation
Vantin, 3rd gen
44
ceftriaxone brand and generation
Rocephin, 3rd gen
45
cefotaxime brand and generation
Claforen, 3rd gen
46
Ceftazadime brand and generation
Fortax, 3rd gen
47
cefepime brand and generation
Maxipime, 4th gen
48
ceftaroline brand and generation
Teflare, 5th gen
49
monobactams
aztreonam
50
aztreonam brand
Azactam
51
aztreonam spectrum
narrow, mostly gram -
52
carbapenems
irtapenem/cilastatin, meropenem, ertapenem, doripenem
53
carbapenem spectrum
broad, gram + and gram -, not MRSA
54
carbapenem route
parenteral
55
imipenem + cilastatin
Tienam
56
meropenem brand
Merrem
57
ertapenem brand
InVanz
58
doripenem brand
Doribax
59
major carbapenem AE
seizures