Exam 2 Flashcards by Ellen Schafer

Q

quinolone MOA

A

inhibit topoisomerase IV and DNA gyrase

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Q

nalidixic acid

A

1st gen quinolone

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Q

pipermidic acid

A

1st gen quinolone

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Q

oxolinic acid

A

1st gen quinolone

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Q

cinoxacin

A

1st gen quinolone

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Q

norfloxacin

A

2nd gen quinolone; fluoroquinolone

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Q

ciprofloxacin

A

2nd gen quinolone; fluoroquinolone

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Q

ofloxacin

A

2nd gen quinolone; fluoroquinolone

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Q

levofloxacin

A

3rd gen quinolone; fluoroquinolone

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Q

gemifloxacin

A

4th gen quinolone; fluoroquinolone

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Q

moxifloxacin

A

4th gen quinolone; fluoroquinolone

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Q

norfloxacin brand

A

Noroxin

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Q

ciprofloxacin brand

A

Cipro

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Q

ofloxacin brand

A

Floxacin

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Q

levofloxacin brand

A

Levaquin

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Q

gemifloxacin brand

A

Factive

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Q

moxifloxacin brand

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A

Avelox

Q

major quinolone SE

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A

tendonitis and tendon rupture

Q

quinolone DI

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A

theophylline
NSAIDs
polyvalent metal ions

Q

quinolone that inhibit CYP1A2

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A

norfloxacin, ciprofloxacin

Q

dont take quinolones if

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A

under 18
pregnant
history of epilepsy

Q

aminoglycoside MOA

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A

bind to the 16s RNA of the 30s ribosome in the A site

Q

aminoglycoside SE

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A

nephrotoxicity

ototoxicity

Q

aminoglycoside DI

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A

NSAIDs
diuretics
vancomycin

aminoglycoside pregnancy category

D (except paromomycin)

gentamicin brand

Gentak

tobramycin brand

Tobi

amikacin brand

Amikin

neomycin brand

NeoFrandin

macrolide MOA

bind 23s RNA of 50s ribosome

Erythromycin ethyl succinate brand

EryPed

clarithromycin brand

Biaxin

azithromycin brand

Zmax, Zithromax

telithromycin brand

Ketek

Fidaxomicin brand

Dificid

tetracycline brand

Sumycin, Actisite

Doxycycline brand

Oracea, Doryx, Doxy, Adoxa

demeclocycline brand

Declomycin

Minocycline brand

Dynacin, Minocin, Solodyn, Vectrin, Arestin

Tigecycline brand

Tygacil