BONES Flashcards
Yellow marrow
made of adipocytes can be used as energy stores
Cortical bone
80% of bone 20% of remodelling
dense structural bone type
osteon
found in cortical bone
makes concentric layers
central Haversian canal
founding cortical bone, BV, nerves, fluid
Volkmann canals
found in cortical bone, transverse
canaliculi
found in cortical bone, links osteocytes lunicae
Trabecular bone
20% of bone 80% of remodelling
remodels from mechanical loading
what is bone made of
hydroxyapatite crystals
10:6 Ca:PO4 (matrix)
Collagen fibers (type 1)
increase tensile strength
Osteoblasts
immature bone cells
formed from mesenchymal cells
produce osteoid to do osteogenesis
close themselves in and become osteocytes
Osteoprogenitor cells
Stem cells that sit on inner layer of periosteum and project to endosperm
osteoclasts
Multinucleated cells (50-150)
formed by fusion of recruited monocyte/macrophage
secrete acids for resorption
ARRF
bone remodelling
Activation- resorption- reversal- formation
Intramembranous ossification
Bone development from fibrous tissue
Endochondral ossification
bone forms from cartilage scaffold called anlage
Spicules
specific voids in intramembranous bone from BV envelopment by osteoblast activity
Intramembranous bones
Clavicle, mandible, skull/face
Chondrocytes
form cartilage
perichondria cells
form the periosteum in endochondral ossification
endochondral ossification
starts in the cartilage anlage when cells enlarge and grow outward, then die and are replaced by osteoblasts forming and primary ossification centre
secondary ossification center
found in the epiphysis also replacing cartilage with bone, extends bones
Epiphyseal growth plate
Gap of chondrocytes between primary and secondary ossification centres
Epiphyseal line
from the closure of the gap once growing is done
articular cartilage
cartilage at the end of bone as a cap
appositional growth
Periosteum layer keeps growing outwards using circumferential lamellae while forming osteons around BV