Endocrine Flashcards

(43 cards)

1
Q

Types of hormones

A

Amino acid derivatives
Peptide
Lipid derivatives

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2
Q

hypothalamus function

A

Integrates neural and endocrine
secretes to posterior and anterior pituitary
Has autonomic enters to control adrenal medulla

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3
Q

infundibulum

A

attachment between hypothalamus and pituitary

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4
Q

hypophyseal portal system

A

hypothalamus secretes into this to control anterior pituitary
-breaks of the primary plexus of capillaries in the infundibulum

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5
Q

anterior lobe regions

A

Pars distalis (most hormones)
pars intermedia (melanocyte stimulating hormone)
pars tuberalis (wraps around infundibulum

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6
Q

thyrotropes

A

TSH

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7
Q

Corticotropes

A

ACTH
MSH (melanocyte stimulating hormone)

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8
Q

Gonadotropes

A

FSH, LH

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9
Q

Lactotropes

A

Prolactin

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10
Q

Somatotropes

A

GH (somatotropin)

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11
Q

MSH secretion

A

from pars intermedia in anterior pituitary

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12
Q

TSH action

A

Causes thyroid hormone release
-calcitonin
-T3 and T4

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13
Q

ACTH action

A

targets adrenal cortex to release glucocorticoids

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14
Q

FSH action

A

targets Sertoli cells to produce sperm. or ovaries to produce estrogen and inhibin

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15
Q

LH action

A

Targets leydig cells to produce androgens (testosterone)
targets ovaries to ovulate and produce progesterone

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16
Q

GH action

A

All cells increase protein synthesis, catabolism
also targets liver to release somatomedins (further of same effects

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17
Q

MSH action

A

targets melanocytes to cause melanin

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18
Q

ADH action

A

(vasopressin)
In response to increased NaCl or low BP
causes water retention and constricts peripheral BV

19
Q

Oxytocin action

A

Contraction (uterus, boobies)
in males contracts prostate

20
Q

Thyroid gland structure

A

Highly vascularized
has two lobes connected by isthmus

21
Q

thyroid hormone production

A

Occurs in colloid, T thyrocytes secrete thyroglobulin which is processed to T4/3 on the apical side by thyroid peroxidase

22
Q

C tyrocytes

A

within the thyroid
produce calcitonin
inhibits osteoclasts lowering Ca+ conc in blood

23
Q

Parathyroid glands

A

posterior to thyroid
has parathyroid cells and oxyphil cells

24
Q

Parathyroid cells

A

Produce PTH
reduces excretion of Ca+ and increases absorption via calcitriol
starts osteoclasts to cause bone reabsorption

25
oxyphil cells
in the parathyroid action unknown but thought to support PTH
26
Zona Glomerulosa
outmost adrenal cortex layer produces aldosterone (mineralocorticoid)
27
Zona fasciculate
middle layer of adrenal cortex Process glucocorticoids cortisol
28
Zona reticularis
deepest layer of adrenal cortex produces androgens
29
Aldosterone action
retains sodium and water increase blood volume e
30
cortisol action
stress hormone, targets liver to produce glucose and glycogen (energy)
31
Adrenal medulla
contains two Chromatin cell types produce epinephrine and norepinephrine
32
Kidney hormones
Renin Erythropoietin Calcitriol
33
Heart hormones
Atrial natriuretic peptide
34
RAAS system
Kidney responds to low BP by producing renin, renin coverts angiotensinogen to angiotensin 1, ACE coverts A1 to angiotensin 2, A2 stimulates aldosterone secretion aldosterone also constricts BV further increasing BP
35
Calcitriol production
Vit D cholecalciferol (skin + diet), covered to intermediate in liver, then to skin for activation, back to liver for calcitriol
36
atrial natriuretic peptide
Right atrium detects high BP and releases this, it inhibits ADH and aldosterone, loss of water and ions lower blood volume
37
Alpha cells
Secrete glucagon is islets stimulates liver catabolism of glycogen to glucose for energy
38
Beta cells
secrete insulin from islets increase glucose absorption
39
Delta cells
secrete somatostatin from islets Inhibits metabolism and growth (less glucagon, less insulin)
40
F cells
secrete pancreatic polypeptide from islets inhibits gallbladder regulates pancreatic enzymes
41
Pineal glands
Part of epithalamus pinealocytes secrete melatonin
42
melatonin action
slows sperm, oocytes and reproductive organs controls eepy
43