Endocrine Flashcards
(43 cards)
Types of hormones
Amino acid derivatives
Peptide
Lipid derivatives
hypothalamus function
Integrates neural and endocrine
secretes to posterior and anterior pituitary
Has autonomic enters to control adrenal medulla
infundibulum
attachment between hypothalamus and pituitary
hypophyseal portal system
hypothalamus secretes into this to control anterior pituitary
-breaks of the primary plexus of capillaries in the infundibulum
anterior lobe regions
Pars distalis (most hormones)
pars intermedia (melanocyte stimulating hormone)
pars tuberalis (wraps around infundibulum
thyrotropes
TSH
Corticotropes
ACTH
MSH (melanocyte stimulating hormone)
Gonadotropes
FSH, LH
Lactotropes
Prolactin
Somatotropes
GH (somatotropin)
MSH secretion
from pars intermedia in anterior pituitary
TSH action
Causes thyroid hormone release
-calcitonin
-T3 and T4
ACTH action
targets adrenal cortex to release glucocorticoids
FSH action
targets Sertoli cells to produce sperm. or ovaries to produce estrogen and inhibin
LH action
Targets leydig cells to produce androgens (testosterone)
targets ovaries to ovulate and produce progesterone
GH action
All cells increase protein synthesis, catabolism
also targets liver to release somatomedins (further of same effects
MSH action
targets melanocytes to cause melanin
ADH action
(vasopressin)
In response to increased NaCl or low BP
causes water retention and constricts peripheral BV
Oxytocin action
Contraction (uterus, boobies)
in males contracts prostate
Thyroid gland structure
Highly vascularized
has two lobes connected by isthmus
thyroid hormone production
Occurs in colloid, T thyrocytes secrete thyroglobulin which is processed to T4/3 on the apical side by thyroid peroxidase
C tyrocytes
within the thyroid
produce calcitonin
inhibits osteoclasts lowering Ca+ conc in blood
Parathyroid glands
posterior to thyroid
has parathyroid cells and oxyphil cells
Parathyroid cells
Produce PTH
reduces excretion of Ca+ and increases absorption via calcitriol
starts osteoclasts to cause bone reabsorption