Book Ch. 33

Question 1

methotrexate complications

5

Answer 1

1. increased risk of infection
2. hepatic fibrosis and toxicity
3. BMS
4. ulcerative stomatitis/GI ulcer
5. fetal death/congenital abnorm.

Question 2

hydroxychloroquine complications

1

Answer 2

1. retinal damage/blindness

Question 3

adalimumab is administered what route

Answer 3

sub q

Question 4

a/e - rhabdo

Answer 4

colchicine - gout antiinflammatory

Question 5

DMARDs

2

Answer 5

1. methotrexate

2. hydroxychloroquine

Question 6

retinal damage

Answer 6

hydroxychloroquine

Question 7

gluco. for gout

Answer 7

prednisone

Question 8

milnacipran

Answer 8

snri - fibrom.

Question 9

duloxetine

Answer 9

snri - fibrom.

Question 10

nsaids for gout

3

Answer 10

1. indomethacin
2. naproxen
3. diclofenac

Question 11

DMARDs therap. uses

5

Answer 11

1. analgesia for pain, swelling, and joint stiffness
2. maintenance of joint function
3. slow/delay the worsening of the disease
4. prevent organ rejection
5. manage IBD

Question 12

give with folic acid to reduce GI and hepatic toxicity

Answer 12

methotrexate

Question 13

cyclosporine complications

5

Answer 13

1. risk of infection
2. hepatotoxicity/jaundice
3. nephrotoxicity
4. hirsutism
5. gingival hyperplasia

Question 14

antigout antiinflamm. agent

1

Answer 14

colchicine

Question 15

a/e to monitor for - allopurinol

3

Answer 15

1. nausea
2. rash
3. increased gout pain

Question 16

etanercept med. administration

3

Answer 16

1. sq injection 2/day
2. monitor site for infection
3. rotate sites

Question 17

inhibit uric acid production

Answer 17

allopurinol

Question 18

belimumab tx

Answer 18

sle

Question 19

colchicine complications

4

Answer 19

1. mild GI distress
2. BMS
3. thrombocytopenia
4. rhabdo

Question 20

a/e of etanercept

4

Answer 20

1. severe infections
2. HF
3. severe skin reaction - steven johnson syndrome
4. hematologic disorders

Question 21

antimalarial agent is to

Answer 21

hydroxychloroquine

Question 22

med for fibromy. - SNRI

2

Answer 22

duloxetine

milnacipran

Question 23

colchicine is to

Answer 23

only effective for inflammation caused by gout

Question 24

gold salts is to

Answer 24

auranofin

Question 25

belimumab complications | 6

Answer 25

1. GI effects 2. headache 3. depressed mood 4. insomnia 5. infusion reaction 6. increased risk of infection

Question 26

a/e - gingival hyperplasia, hirsutism

Answer 26

cyclosporine

Question 27

etanercept therap. uses

Answer 27

DMARD classified as a tumor necrosis factor antagonists - suppresses manifestations of mod to severe RA

Question 28

tumor necrosis factor antagonists | 2

Answer 28

1. etanercept | 2. infliximab

Question 29

auranofin complications | 5

Answer 29

1. toxicity - pruritis, rashes, stomatitis 2. renal toxicity - proteinuria 3. blood dyscrasias 4. hepatitis 5. GI upset

Question 30

allopurinol complications | 5

Answer 30

1. hypersensitivity reaction 2. kidney injury 3. hepatitis 4. GI distress 5. increase in gout attacks - during 1st month of tx.

Question 31

agents for hyperuricemia | 3

Answer 31

1. allopurinol 2. febuxostat 3. probenecid

Question 32

DMARDs pharm action | 3

Answer 32

1. slow joint degnerations and progression of RA 2. relief of inflammation and pain 3. delay disease progression

Question 33

med for SLE

Answer 33

belimumab