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Flashcards in BPH and ED Deck (20)
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1

Population related risks for prostate enlargement

BPH more common in American/Australian and less common in Asian cultures

2

Tests and exams for diagnosis of BPH

AUA symptom index, DRE, neuro exam, UA, PSA

3

Relax smooth muscle of the prostate and bladder neck without interfering with bladder contractility.
Decrease bladder resistance to urinary outflow
Work quickly and increase urinary flow

α-blockers , Alpha-1 adrenergic antagonists

4

Major side effect of α-blockers , Alpha-1 adrenergic antagonists

orthostatic hypotension

5

Name the α-blockers , Alpha-1 adrenergic antagonists

tamsulosin (flomax), doxazosin (cardura), Terazosin (Hytrin)

6

α-blockers , Alpha-1 adrenergic antagonist that causes less orthostatic HTN/fluid retention but may cause floppy iris syndrome

tamsulosin (flomax)

7

α-blockers , Alpha-1 adrenergic antagonist that may have secondary benefit to patients with cardiac dz

doxazosin (cardura)

8

α-blockers , Alpha-1 adrenergic antagonist often used for HTN and should be taken at bedtime to avoid hypotension

terazosin (hytrin)

9

Blocks 5-alpha reductase, the enzyme that activates testosterone in the prostate.
Impairs prostate growth by inhibiting the conversion of testosterone to dihydrotestosterone

5-α-Reductase inhibitors

10

What zone of the prostate doe 5-α-Reductase inhibitors
cause changes in the epithelial cells?

transition zone

11

Name the 5-α-Reductase inhibitors

Finasteride (Proscar) and Dutasteride (Avodart)

12

Antagonizes acetylcholine receptors. Used to help urgency symptoms by stabilizing the detrusor muscle

antimuscarinics

13

Herb derived from dark berries of a palm tree. Inhibits testosterone conversion to DHT. Stops DHT at receptor sites

saw palmetto

14

Vitamin that may prevent or decrease prostate enlargement

zinc

15

Name the PDE-5 inhibitors

Sildenafil (Viagra), Vardenafil (Levitra), Tadalafil (Cialis)

16

Work by blocking the action of type 5 phosphodiesterase maintaining vasodilation and increased blood flow to the penis

PDE-5 inhibitors

17

What should be avoided in patient who is taking a PDE-5 inhibitors due to sharp decrease in BP?

nitrates

18

Use for patients with ED who have contraindications to 5 PDE inhibitors. Available as intracavernosal injection or intraurethral suppository

Alprostadil (PGE1)

19

Should be avoided in patients with leukemia, myeloma, or sickle cell anemia or sickle cell trait

alprostadil

20

Treatment for premature ejaculation

SSRIs (fluoxetine or paroxetine) or TCA (clomipramine)