Brain Cells Flashcards

(61 cards)

1
Q

Neuron

A

Brain Cells which sense changes in the environment, communicate this to other neurons and cells and finally decides on the bodies response

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2
Q

Glial Cell

A

Supporting brain cells which insulate and support Neurons

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3
Q

Histology

A

The Study of tissues and cells via a microscope

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4
Q

Nissl Stain

A

Dye used to stain the cell body of Neurons

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5
Q

cytoarchitecture

A

the arrangement of neurons all over the brain

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6
Q

FormalAldehyde

A

Chemical compounds with formula H−CHO, when used on a brain it will harden it, making it easier to study via microscope

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7
Q

Microtome

A

Device used to slice brain very thinly

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8
Q

Golgi Stain

A

Staining method that completely stains a small fraction of neurons allowing the whole cell to be examined

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9
Q

soma

A

Also called cell body and Perikaryon.
20 micrometers in diameter
filled with cytosol and organelles

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10
Q

Neuron Doctrine

A

neurons communicate by contact not continuity. Thus they are not an exception to cell theory, this was proven by studies with an electron microscope

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11
Q

Nucleus

A

Location of DNA. Gene expression influenced by transcription factors leading to many different forms of cells

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12
Q

Transcription and Translation

A

Process of converting genetic material into functional proteins

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13
Q

Genome

A

Entire length of DNA

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14
Q

Genetic Engineering

A

Artificially mutating DNA to observe it’s effects on a test subject

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15
Q

Knock Out Mice

A

A specific gene is removed from the genome of these mice so they can study the effect of this gene. Often used to study progression of diseases

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16
Q

transgenic mice

A

New genes are introduced and overexpressed

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17
Q

Knock In mice

A

A specific gene is implanted into the genome of these mice so they can study the effect of this gene. Often used to study progression of diseases

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18
Q

Rough Endoplasmic Reticulum

A

RER
Makes proteins, thus very important for brain function and are very numerous in neurons.
Also make proteins for external use

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19
Q

Free ribosomes

A

Sites of protein synthesis, especially for proteins that will be used internally

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20
Q

Polyribosomes

A

Strings of free ribosomes producing the same proteins

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21
Q

Smooth Endoplasmic Reticulum

A

SER
regulates internal cell condition (eg Ca2+ ion levels)

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22
Q

Golgi Apparatus

A

Sorts proteins depending on end purpose

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23
Q

Mitochondrion

A

Convert ADP to ATP via cellular respiration
1 micrometer
super super important for neurons

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24
Q

Adenosine Triphosphate

A

ATP
energy currency within cells

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25
Neuronal Membrane
barrier around neuron to separate cytoplasm with extracellular fluid. Rich in proteins for communication and cell maintenance
26
Cytoskeleton
Scaffolding of a neuron Consists of microtubules, microfilaments and neurofilaments
27
Microtubules
big hollow pipes issues with this are associated with alzheimers
28
Microfilaments
small braid consisting of 2 actin strands, work like a spiders web and are constantly rebuilt and changed
29
Neurofilaments
Long proteins, work as the bones of the cell
30
Axon
One is found on each Neuron, where outgoing messages are sent from. Consists of axon hillock, axon collaterals, and axon terminal Contains no ribosomes so proteins must be transported to it Also has unique composition of membrane proteins Pre synaptic portion
31
Axon Hillock
initial segment of axon, where IPSPS and EPSPS summate
32
Axon Collaterals
Branches of Axon that spread to various parts of nervous system
33
Axon Terminal
Where Nt Vesicles are released. Microtubules are not present dense covering of proteins on membrane many mitochondria
34
anterograde transport
Soma to Axon
35
Retrograde transport
Axon to Soma
36
Synapse
Point of connection between 2 neurons
37
Presynaptic cell
Cell sending message
38
Postsynaptic cell
Cell receiving cell
39
Synaptic Transmission
Process of turning an electrical message to a chemical one back to an electrical one
40
Synaptic cleft
place where NT diffuse across
41
Neurotransmitters
Chemical messengers inside the brain. Released by vesicles in presynaptic cell into synaptic cleft where they diffuse across before binding to receptors on the post synaptic cell to induce an electrical message
42
Axoplasmic transport
Movement of materials like proteins from the soma to axon. Materials bundled in a vesicle which is then moved by a protein called Kinesin
43
Neurites
collect term for dendrites and axons
44
Dendrite
Attenae of neurons. They receive messages from neighbouring cells. Branches in many directions to recieve many messages. Covered in thousands of synapses and even more receptors
45
Dendritic Tree
All dendrites of a specific cell
46
Dendritic Spines
isolate chemical reactions. Issues with these has a strong link to cognitive impairments and intellectual disability.
47
Unipolar
Neuron with one neurite
48
Bipolar
Neuron with two nuerites
49
Multipolar
Neuron with many neurites
50
Classification based on dendrites
Specific to brain location so there are many
51
Spiny
Neurons with dendritic spines
52
Aspinous
Neurons without dendritic spines
53
primary sensory neurons
cells connected to sensory information
54
motor neurons
cells that control muscles and movement
55
interneurons
neurons only connected to other neurons
56
Cholinergic neurons
Neurons that release Acetylcholine, this includes most cells involved in movement
57
Astrocytes
Most common glia cell regulate chemical content in extracellular space and clean up excess NTs via specialised proteins
58
Oliodendrogial Cells
Glia cell Compose the myelin sheath allowing propagation of nerve impulses located in CNS
59
Schwann Cells
Glia cells Compose the myelin sheath allowing propagation of nerve impulses located in PNS
60
Ependymal cells
line fluid filled ventricles big for brain development
61
Microglia
Work as phagocytes within the brain