Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

FINALS > Breast > Flashcards

Breast Flashcards

1
Q

When to 2ww

A
  • unexplained lump >30
  • Unilateral nipple changes >50
  • Skin changes
    Non urgent referral
  • Unexplained lump in <30
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Whats in triple assessment

A
  • Clinical assessment
  • Imaging = USS, mammography
  • Histology = fine needle, core biopsy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Fibroadenoma

A
  • Benign tumours of stromal/epithelial
  • painless, smooth, round
  • Mobile
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Fibrocystic breast changes

A
  • Benign
  • stroma, ducts and lobules respond to hormons = fibrous and cystic
  • lumpy, tender, size change
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Mx fibrocystic

A
  • good bra
  • NSAIDs
  • Heat
  • Hormonal tx
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Breast cysts

A
  • Benign individual fluid filled lumps
  • Smooth
  • Well defined
  • Mobile
  • Can be fluctuant
  • assess to exclude cancer
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Fat necrosis

A
  • benign lump
  • localised degeneration and scarring of fat tissue #- localised trauma, radiotherapy or surgery
  • Painless, firm, irregular, fixed
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Lipoma

A
  • Benign tumour of adipose
  • Soft, painless, mobile, no skin changes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Non cyclical breast pain causes

A
  • Medications = HRT
  • infection
  • Pregnancy
  • Cancer
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

presentaiton mammary duct ectasia

A
  • discharge
  • tenderness
  • retraction or invesrion
  • breast lump
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Mx MDE

A
  • triple assessment
  • Mammogram = microcalcifications
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

intraductal papilloma

A
  • warty lesion in duct
  • nipple discharge, pain, lump
  • triple assessment
  • mx = surgery
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

mx mastitis

A
  • continue breastfeeding
  • flucloxacillin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Mx breast abscess

A
  • non lactational = co amoc, or macrolides plus met
  • refer to on call surgery
  • abx
  • USS
  • drainage
  • culture
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

pagets

A
  • eczematous change due to underlying malignancy
  • suspect if eczema not resolved in 2w
  • surgery
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

DCIS

A
  • pre cancerous or cancerous epithelial cells of ducts
  • localised
  • mammogram screening pick up
  • full excision
17
Q

LCIS

A
  • pre cancerous
  • asymptomatic and undetectable on mammogram
  • breast biopsy
  • mx close monitoring
18
Q

invasive ductal carcinoma

A
  • originate in cells from breast ducts
  • seen on mammogram
19
Q

invasive lobular carcinoma

A
  • cells from rbeast lobules
20
Q

inflammatory breast cancer

A
  • 1-3%
  • similar px to abscess/mastitis but no response to abx
21
Q

breast screening age?

A
  • mammogram 3 yearly ages 50-70 (47-73)
22
Q

who count as high risk

A
  • 1st degree relative with breast cancer under 40
  • 1st deree male relative
  • 1st degree with bilateral <50
  • 2 1st degree
    = annual mammogram
23
Q

chemoprevention for high risk

A
  • tamoxifen if pre menopausal
  • anastrozole if post
24
Q

3 receptors tested for

A
  • oestrogen receptors
  • progesterone receptors
  • human epidermal growth factor
    triple negaive = poor prognosis
25
Q

features of locally advanced cancer

A
  • ulceration
  • peau d’orange
  • inflammatory breast cancer
  • fixed to chest wall
  • fixed, matted axillary ln
26
Q

primary tx

A

-tx intended to cure, or to allow easier or lesser surgery

27
Q

adjuvant tx

A
  • any treatment given following primary treatment to prevent recurrence or mets
28
Q

radiotherapy

A
  • used in breast conserving surgery to reduce recurrence
29
Q

3 scenarios for chemo

A
  • neoadjuvant = shrink pre surgery
  • adjuvant = after surgery to reduce recurrence
  • tx of mets
30
Q

meds to oestroge positive

A
  • tamoxifen for pre menopause
  • aromatase inhibitors for post = letrozole
31
Q

tamoxifen is

A
  • selective oestrogen receptor modulator
  • blocks ER in breast
  • Stimulates Er in bones and uterus
32
Q

amromatase inhibitors work by

A
  • aromatase converts androgens to oestrogen
  • inhibs work by blocking creating of oestrogen in fat tissue
33
Q

trastuzumab is

A
  • monoclonal antibody that targets HER2
34
Q

surveillance mammograms every

A
  • yearly for 5 years
35
Q

mastectomy if

A
  • multifocal tumour
  • central tumour
  • large lesion in small breast
  • DCIS >4cm
36
Q

wide local excision if

A
  • solitary lesion
  • peripheral tumour
  • small lesion large breast
  • DCIS <4cm
37
Q

adverse effects Tamoxifen

A
  • mesntrual disturbance
  • hot flushes
  • VTE
  • endometrial cancer
38
Q

anastrozole adverse effects

A
  • osteoporosis (DEXA before intiating)
  • hot flushes
  • arthralgia
  • insomnia
39
Q
A

FINALS (31 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions