Flashcards in Breast Deck (9)
What is gynectomasia? it s cause?
adult male breast enlargement; increase in the estrogen/amdrogen ratio
What metabolic disorders are associated with increased conversion of androstenedione into estrogens? (as seen in males)
Liver disease (Micronodular Cirrhosis- impairs hepatic estrogen metabolism) and Hyperthyroidism
What are the classes of non comedo intraductal carcinoma?
Micropapillary, Cribriform, and Solid
Which DCIS type is likely to produce a desmoplastic response in surrounding tissue?
Comedo- produces a dense collagenous stroma
What is the gene and the protein associated with HER2-neu that can be detected in HER2/neu overexpression in FISH?
c-erbB2 protein and the HER2/neu gene
What does colloid carcinoma feature?
What is Medullary carcnioma conmposed of ?
sheets of invasive and pleomorphic cells
What cells are proliferative in Phyllodes Tumor?
Spindly stromal cells