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Flashcards in Breast Deck (9)
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1

What is gynectomasia? it s cause?

adult male breast enlargement; increase in the estrogen/amdrogen ratio

2

What metabolic disorders are associated with increased conversion of androstenedione into estrogens? (as seen in males)

Liver disease (Micronodular Cirrhosis- impairs hepatic estrogen metabolism) and Hyperthyroidism

3

What are the classes of non comedo intraductal carcinoma?

Micropapillary, Cribriform, and Solid

4

Which DCIS type is likely to produce a desmoplastic response in surrounding tissue?

Comedo- produces a dense collagenous stroma

5

What is the gene and the protein associated with HER2-neu that can be detected in HER2/neu overexpression in FISH?

c-erbB2 protein and the HER2/neu gene

6

What does colloid carcinoma feature?

Mucin production

7

What is Medullary carcnioma conmposed of ?

sheets of invasive and pleomorphic cells

8

What cells are proliferative in Phyllodes Tumor?

Spindly stromal cells

9

What are 2 major clinical manifestations of inflammation of the breast?

Pain with breast enlargement