Flashcards in Breast Development/Physiology Deck (19):
Is pregnancy protective against breast cancer?
Yes (however, for a few years after there is increased risk, the RR is below 1 ~20 years after 1st birth)
Is breastfeeding protective against breast cancer?
What is the AAP stand on breastfeeding?
All newborns should be breastfed for 6 months
What are the newborn benefits of breastfeeding?
What are the maternal benefits of breastfeeding?
Decreased postpartum bleeding
More rapid uterine involution
Increased child spacing
Earlier return to pre-pregnancy weight
What is the major component that comprises the breast in a lactating woman vs a non-lactating woman?
Lactating- glandular tissue
Non-lactating- adipose tissue
What is the embryologic origin of the breast?
Ectoderm (primary bud into secondary bud)
Macroscopic development of the breast during puberty is due to the accumulation of what type of tissue?
What hormone regulates ductal growth during the menstrual cycle?
What hormone regulates alveoli growth during the menstrual cycle?
What is the source of progesterone during the menstrual cycle?
Corpus luteum- if egg implants will continue to secrete progesterone until week 10 when the placenta becomes the primary source
Impaired gonadal maturation can result in breast hypoplasia, how is this treated?
Aside from progesterone, what other hormone aids in formation of mature alveoli?
What hormone inhibits milk secretion?
What 3 hormones regulate lactation?
Progesterone- fall at parturition initiates secretion
Prolactin- maintain milk synthesis/secretion
Oxytocin- stimulates milk ejection
A woman has a small amount of placenta left behind following a birth. Will she be able to breastfeed?
No- placenta produces enough progesterone to prevent milk secretion
A baby suckling leads to inhibition of what neurons in the hypothalamus?
Dopaminergic- increases prolactin
(suckling also leads to increased oxytocin)
What vitamin must be given to infants who are exclusively breast fed?
Failure to start breastfeeding shortly after birth leads to decreased prolactin signaling leading to decreased milk synthesis/secretion. What population is this a particular problem for?
Women that deliver preterm infants