Flashcards in Pharmacology During Pregnancy Deck (16):
Why are NSAIDs generally contraindicated in late stage pregnancy?
Prostaglandins play a critical role in initiation of labor- contract uterine SM, promote formation of gap junctions
What is cervical dilation dependent upon?
What stimulates uterine contractions?
What receptors modulate uterine relaxation?
What does HELLP syndrome stand for?
Elevated liver enzymes
What gel contains prostaglandin E2 and promotes cervical effacement when applied vaginally?
Oxytocin has no effect on cervical dilation, what is its use?
Labor induction after cervical ripening
Post partum hemorrhage
What agents can be given if oxytocin is ineffective at treating postpartum hemorrhage?
What drug is most commonly used to inhibit labor?
What β2 agonist can be used to inhibit labor? How long can this medication be used?
48-72 hours (potential for serious maternal heart problems/death)
What is the safest NSAID to use during pregnancy?
How can you medically treat an abortion?
Mifepristone- progesterone antagonist
Misoprostol- prostaglandin E1 analog
What is generally considered the first line therapy for organic impotence?
List 3 PDEIs.
What is the MOA of PDEIs?
Block cGMP breakdown
Enhance vascular relaxation
Increase blood flow