Ovarian Disorders

Question 1

What part of the ovary is exposed to the peritoneum?

Answer 1

Surface epithelium

Question 2

What is a corpus albicans?

Answer 2

Ovarian scar composed of connective tissue that forms after the corpus luteum degenerates

Question 3

Where do most ectopic pregnancies occur?

Answer 3

Fallopian tube

Question 4

What is the most common site of endometriosis?

Answer 4

Ovary

Question 5

What is the gross appearance of ovarian endometriosis?

Answer 5

Chocolate cyst

Question 6

How are BRCA1/BRCA2 related to cancer?

Answer 6

DNA repair genes

Question 7

What are the 4 categories of ovarian surface epithelium tumors?

Answer 7

Serous
Mucinous
Endometrioid
Clear cell

Question 8

What is the histologic appearance of an ovarian serous borderline tumor?

Answer 8

Hierarchical branching

Question 9

A laminated/targetoid calcification is seen on histologic examination of a serous cystandenocarcinoma. What is the term given to this finding?

Answer 9

Psammoma bodies

Question 10

What is the most common ovarian malignancy?

Answer 10

Serous cystadenocarcinoma

Question 11

If an ovarian tumor has invaded the stroma is it a borderline tumor or a carcinoma?

Answer 11

Carcinoma

Question 12

Clear cell carcinoma of the ovary is associated with what pathologic condition?

Answer 12

Endometriosis

Question 13

Once resected granulosa cell tumors can be followed using what serum marker?

Answer 13

Inhibin

Question 14

Call-Exner bodies are pathognomonic for what tumor?

Answer 14

Granulosa cell tumor

Question 15

A signet ring cell is noted on a pathology report of a biopsied ovary. What type of tumor is this?

Answer 15

Krukenberg tumor- metastatic gastric carcinoma

Question 16

What are the most common causes of anovulation?

Answer 16

Athletes
Adrenal insufficiency
Cushing syndrome
Eating disorders
Hyperprolactinemia
Obesity
Pregnancy
PCOS
Premature ovarian insufficiency
Thyroid disorders

Question 17

What is the LH:FSH in a woman with PCOS?

Answer 17

Increased

Question 18

What is the most common ovarian mass in young women?

Answer 18

Follicular cyst

Question 19

Theca-lutein cyst are associated with what neoplasitc conditions?

Answer 19

Choriocarcinoma

Hydatidiform mole

Question 20

What is the most common adnexal mass in a woman >55?

Answer 20

Ovarian neoplasm

Question 21

Ovarian neoplasms can arise from what 3 origins?

Answer 21

Surface epithelium
Germ cells
Sex cord stromal tissue

Question 22

What decreases risk for ovarian neoplasms?

Answer 22

Pregnancy
Breast feeding
OCPs
Tubal ligation

Question 23

What tumor marker can be used to monitor progression of ovarian cancer?

Answer 23

CA 125

Question 24

Mucus secreting epithelium lines what benign ovarian neoplasm?

Answer 24

Mucinous cystadenoma

Question 25

What is the most common benign ovarian neoplasm?

Answer 25

Serous cystadenoma

Question 26

What is the most common ovarian tumor in women 20-30 years old?

Answer 26

Mature cystic teratoma

Question 27

What tumor has coffee bean nuclei on H&E stain?

Answer 27

Brenner tumor- looks like bladder

Question 28

What is Meigs syndrome?

Answer 28

Ovarian fibroma Ascites Hydrothorax

Question 29

Are mature or immature teratomas malignant?

Answer 29

Immature

Question 30

Is a mature or immature teratoma more likely to contain thyroid tissue?

Answer 30

Mature

Question 31

Is a mature or immature teratoma more likely to contain neural-like tissue?

Answer 31

Immature

Question 32

What is the most common malignant stromal tumor of the ovary?

Answer 32

Granulosa cell tumor

Question 33

hCG and LDH are tumor markers for the most common ovarian tumor in adolescents. What is the type of tumor?

Answer 33

Dysgerminoma

Question 34

A choriocarcinoma can develop during or after pregnancy in the mother or baby. What is the tissue of origin?

Answer 34

Trophoblstic tissue- cytotrophoblast/syncytiotrophoblast

Question 35

Where do choriocarcinomas metastasize?

Answer 35

Lungs

Question 36

What is the classic clinical picture of a woman with a choriocarcinoma?

Answer 36

Increased hCG Hemoptysis Shortness of breath

Question 37

What tumor is associated with Schiller-Duval bodies?

Answer 37

Yolk sac tumor