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Flashcards in bug to drug Deck (27)
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1

MRSA

some 3rd gen cephalosporins (CTX
some 4th gen cephalosporins (cefepime)

TMP/SMX

macrolides (azithro, clarithro, erythro)

vancomycin

linezolid

clindamycin

2

CoNS

3rd gen cephalosporins (CTX)

4th gen cephalosporins (cefepirne)

vancomycin

3

resistant strep pneumoniae

3rd gen cephalosporins (CTX)

4th gen cephalosporins (cefepirne)

vancomycin

4

VRE

3rd gen cephalosporins (CTX)

4th gen cephalosporins (cefepirne)

daptomycin but not as good for e. faeclum?

5

staph aureus (MSSA)

penicillin
nafcillin
piperacillin, ticarcillin
above + BLI
carbapenems

ist generation cephalospoirns (cefaz/keflex)

3rd generation cephalosporins (CTX)

4th generation cephalosporins (cefepime)

ciprofloxacin
levofloxacin and moxifloxacin work, but work better for staph

aminoglycosides (gent, tobra, erythro)

TMP/SMX (staph more than strep)

vancomycin

linezolid

daptomyin

6

strep pneumo (not resistant)

PCN
ampicillin
amoxicillin
above + BLI
piperacillin, ticarcilin
above + BLI
carbapenems

some 2nd gen cephalosporins (cefurox)

3rd gen cephalosporins (CTX)

4th gen cephalosporins (cefepime)

ciprofloxacin, levofloxacin, moxifloxacin

aminoglycosides (gent, tobra, amik)

TMP/SMX (staph more than strep)

vancomycin

linezolid

daptomyin

7

e. coli
strep A-G
viridans streptococci

Penicillin
piperacillin, ticarcillin
+ BLI
carbapenems

3rd gen cephalosporins (CTX)

4th gen cephalosporins (cefepime)

sometiems ciprofloxacin

aminoglycosides (gent, tobra, amik)
macrolides (azithro, clarithro, erythro)

bancomycin

linezolid

daptomycin

lincomycin

clindamycin

8

oral anaerobes

clindamycin

9

GPR bacteria

b. cereus
b. anthracis
listeria
c. perfringens
c. diff
corynebacteria
nocardia

10

GPR drugs (that work on all)

ampicillin, amoxicillin
carbapenems

levofloxacin, moxifloxacin

11

c. perfringens

PCN

12

listeria

ampicillin or amoxicillin (or PCN?) plus BLI

aminoglycosides (gent, tobra, amik) synergy

13

nocardia

3rd gen cephalosporins (CTX)

TMP/SMX

14

anthrax

ciprofloxacin

15

c. diff

metronidazole

16

GNC bugs

n. meningitids
n. gonorrhea
moraxella

17

GNC drugs

carbapenems
other beta lactams sometimes except nafcillin, diclox (never works)

3rd gen cephalosporins (CTX) sometimes ceftaz

sometimes 2nd gen cephalospoirns (cefurox)

4th gen cephalosporins (cefepime)

monobactam (aztreonam)

all quniolones (ceprofloxacin, levofloxacin, moxifloxacin)

sometimes macrolides (azithromycin, clarithromycin, erythromycin)

18

non-resistant GNR bugs

e coli
h. flu
salmonella
shigella
campylobacter
francisella
yersinia
b. fragilis
prevotella (anaerobes)
legionella
mycoplasma
chlamydia

19

GNRs (all) drugs

piperacillin, ticarcillin
carbapenems

3rd gen cephalosporins (CTX) (Ceftaz)
4th gen cephalosporins (cefepime)

aztreonam

ciprofloxacin

gentomycin, tobra, amik (aminoglycosides)

sometimes TMP/SMX

20

GNR anaerobes

best drug metronidazole!

beta lactams with BLIs
carbapenems

cefotetan (2nd gen cephalo)

moxifloxacin

50% clindamycin

21

E. coli

some ampicillin amoxicillin
add bli for better coverage

keflex/cefaz some (1st ten cephalosporin)
cefurox some (2nd gen)

TMP/SMX some

22

H. flu

cefuroxime (2nd gen cephalosporin)

macrolides (azithro, clarithro, erythro)

23

legionella

levofloxacin
moxifloxacin

macrolides (azithro, clarithro, erythro)

24

atypical GNRs

moxifloxacin

macrolides (azithro, clarithro, erythro)

25

resistant GNRs (bugs)

serratia
pseudomonas
acinetobacter
citrobacter
enterobacter
klebsiella

26

drugs for resistant GNRs

piperacillin, ticarcillin with BLI
carbapenems

3rd gen cephalosporins (ceftaz)

4th gen cephalosporins (cefepime)

sometimes aztreonam

sometimes quinolines (ciprofloxacin, levofloxacin, moxifloxacin)

sometimes aminoglycodises (gentamycin, tobramycin, amik)

27

stentrophomonas

TMP/SMX