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Flashcards in Bugs from Quiz 1 & 2 Deck (52)
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1

Jaw osteomyelitis, Madura Foot, israeli is GPR, looks like ball of hair on gram stain.

Actinomyces (gram positive rod)

2

Just a reminder that ALL GI anaroebes common in diabetic foot and decubitus ulcer osteomyelitis, this is a GNR oral anaerobe.

Bacteroides Fragilis (gram negative rod)

3

-Is the #1 cause of conjunctivitis in neonates. Irritation from silver nitrates. It is an STD.

Chlamydia Trachomatis (intracellular)

4

anaerobic, spore-forming, found in soil, multiple toxins. Gas gangrene, bubbles under skin, crepitus, can cause
necrotizing fasciitis..

Clostridium perfringens (Gram positive rod)

5

Obligate anaerobe, deep wound infections, need a toxoid to vaccine its toxin.

Clostridium tetani (gram positive rod)

6

aerobic, type III (A/B toxin), necrosis in back of throat.

Corynebacterium diptheriae (gram positive rod)

7

Skin colonizer, also called “coryneform bacteria”, prosthetic material infections

Diptheroids (gram positive rod)

8

anaerobic, associated with the septic emboli after Strep Throat. Lemierre’s Syndrome. It is an oral anaerobe.

Fusobacterium (gram negative rod)

9

Causes Gastroenteritis, CNS, Has a regulon, Prfa, signals, allows for entry, is allowed to spread from cell to cell without leaving the cells, helps resist antibodies and antibiotics, has a pore-forming toxin (type 2), associated with Blue Bell ice cream, canteloupe, milk, cheese, deli meats. Can cause granulomatosis infantiseptica, passed thru placenta, gives baby abscesses on skin. Use Ampicillin.

Listeria monocytogenes (gram positive rod)

10

Pulmonary infection and opportunistic disseminated disease in AIDS (CD4 less than 50). Shows abdominal pain, fever, lymphadenopathy. Non-pigmented slow grower, found in water and soil.

Mycobacterium avium-intracellulare (gram positive rod)

11

Rapid Grower

Mycobacterium chelonae/abscessus (GPR)

12

Photochromogenic, more often in men, slow grower, chronic pulmonary disease

Mycobacterium kansasii

13

Hansen’s Disease, Lepromatous (poorly demarcated lesions, multibacilliary) Tuberculoid (well-demaracated, hypopigmentation, granulomatous inflammation and hardly any bacilli (acid-fast))

Mycobacterium leprae

14

Photochromogenic, slow grower, water tank worker, sporotrichoid rash on arm.

Mycobacterium marinum

15

No Cell Wall

Mycoplasma pneumonaie

16

Madura Foot, sporotrichoid rash

Nocardia species (GPR)

17

Animal bites

Pasteurella multocida (GNR)

18

Prosthetic joint infections, as well as Acne.

Propionibacterium acnes (GPR)

19

obligate aerobe, found in water (Hot Tub), hospital rooms, IVDU, can cause secondary infections after burns, If you see green or blue exudate, think Pseudomonas,Hot tub folliculitis, burn infections

Pseudomonas aeruginosa (GNR)

20

Type I toxin, super antigen, toxic shock syndrome, it’s alpha toxin is staph-scalded skin syndrome on babies, exfoliatin toxin is blisterous impetigo, enterotoxin is food poisoning. Main cause of impetigo (epidermis). Main cause of Endocarditis.Can cause folliculitis for those who sweat and play sports. Most common surgical wound infection. Usually purulent lesions (pus). Polyarticular arthritis - bacteremia staph. Vertebral osteomyelitis - Staph. Diabetic Foot ulcer - Staph.

Staphylococcus aureus (GPC in clusters)

21

Prosthetic joint infections, usually deals with CHRONIC, no pus usually, infections associated with surgical wounds.

Staphylococcus epidermidis (GPC coag neg staph)

22

-Common pathogen in neonatal SBI’s, has capsule, beta-hemolytic, Alpha C surface protein, colonizes vagina. Use penicillin or ampicillin..

Streptococcus agalactiae (GPC, GBS, beta-hemolysis, bacitracin negative) in long chains

23

Cause of Impetigo, Erysipelas, Strep Throat, cellulitis, necrotizing fasciitis. Has pyrogenic exotoxin A and B that are superantigens. Has streptolysin O and S toxins, which lyse cells. Also streptokinase, hyaluronidase, dynase.

Streptococcus pyogenes (GPC, GAS)

24

Type III toxin (A/B), along with diptheria, pertussis, botulism, tetanus, shiga.

Vibrio cholera (GNR)

25

Hemorrhagic vesicles (blisters), salt water

Vibrio vulnificus (GNR)

26

Hand, foot, and mouth disease.

Coxsackievirus A

27

Blood, Saliva, Sex, sits in ductal epithelium and leukocytes, most common
congenital infection in US, hearing loss plus microencephaly. Do PCR of
saliva, treat with Ganciclovir.

CMV

28

Saliva, sits in oropharyngeal epithelium and B cells, Burkitt lymphoma, Hodkin’s lymphoma, Nasopharyngeal carcionoma. Icosahedral.

EBV

29

Transmitted from skin, sits in epithelial cells and neurons, can cause infections in both epidermis and dermis, grouped papulovesicles following dermatome, usually unilateral.. Multi-nucleated keratinocytes.peripheral marginization of chromatin, Tzanck smear. True for All herpes viruses, including chicken pox. Icosahedral.
HSV*(HHV*1*and*2)*
– Latent*spinal*sensory*ganglia*
– HSV*1:*oral*lesions*(less*likely*genital),*temporal*lobe*encephali0s*older*children** and*adults*
– HSV*2:*genital*lesions,*meningi0s,*neonatal*disease*(eye,*nose,** mouth,*disseminated)*
VZV*(HHVI3)*
– Latent*in*the*trigeminal*and*dorsal*root*ganglia* – Chicken*pox,*shingles,*meningi0s/encephali0s*
EBV*(HHVI4) (Oncogenic Virus)
– Latent*in*memory*B*cells*
– Mononucelosis*(heterophile*Abs*+*monospot)*,*Burkie’s*and*Hodgkin’s* *lymphoma,*PTLD,*nasopharygenial*carcinoma*
CMV*(HHVI5)*
– Latent*in*cells*of*the*myeloid*linage.*Mononucelosis*(nega0ve*monospot),* broad*range*of*diseases*in*immunocompromised*host,*neonatal*infection
Tzank*smear*mul0nucleated*giant*cell*
Owls*eyes*intranuclear**inclusions*
HHVI6*
– Latent*in*lymphocytes*
– Exanthem*subitum*(a.k.a*roseola*or*fourth*disease*6moI3yrs),*immunocpmpromised*hosts*
HHVI8 (KSHV) (Oncogenic Virus)
– Latency*unknown*
– Kaposi’s*sarcoma*(HIV)*and*mul0centric*Castle’s*disease*

Herpes Simplex Virus (DNA)

30

Saliva, sits in endothelium and B cells

KSHV (a type of HSV) (DNA)