Cancer Tutorial Flashcards

1
Q

What is a neoplasm

(pro, organ, coor, malig/benign)

A

Abnormal growth of tissue

Typified by:
- Unregulated cell proliferation
- Lack of structural organisation
- Lack of functional coordination with normal tissue
- Forms a mass which can be malignant/benign

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2
Q

Cancer is the …. most common cause of death in the US

A

2nd

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3
Q

4 main treatments for cancer

A

Surgery
Radiation
Chemotherapy
Biotherapy

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4
Q

Top 5 cancers (what percentage do they account for?)

A

Prostate (1)
Breast (2)
Melanoma (3)
Bowel
Lung

Accounts for 60% of cases

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5
Q

1… in how many Australians will be diagnosed with cancer?

A

1 in 2

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6
Q

How much does Cancer cost the health system

A

$4.5 billion

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7
Q

Causes of cancer

A

Carcinogens (radionuclide/radiation) eg UV, asbestos, chemicals and tobacco

Lifestyle factors eg smoking, alcohol, diet

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8
Q

One in …. cancers and one in …. deaths are due to…

A

One in 9 cancers
One in 5 cancer deaths

ARE DUE TO SMOKING

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9
Q

What environmental property can cause prostate cancer

A

Cadium

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10
Q

What environmental property can cause leukemia cancer

A

Ethylene

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11
Q

What environmental property can cause Lung & GI cancer

A

Asbestos

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12
Q

What environmental property can cause Leukemia & Hodgkins cancer

A

Benzene

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13
Q

Cancer ratio 50-59

A

1:20

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14
Q

Cancer ratio 60:69

A

1:10

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15
Q

Cancer ratio 70-79

A

1:5

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16
Q

Cancer ratio 80-89

A

1:3

17
Q

What intensity should be utiliesd

A

Moderate (too intense decreases immunity)

18
Q

How does exercise prevent tumour initiation and progression

A

Enhances/modifies carcinogen activation

Enhances CYP system (cytochrome P450)

Enhance selective enzymes in the carcinogen detoxification pathway

19
Q

Exercise dampens the process involved in the promotion and progression of carcinogenesis by:

A

Scavenging ROS (reactive oxygen species)
Reducing inflammation
Suppressing angiogenesis
Altering cell proliferation, apoptosis & differentiation