Cardiac Tissue Flashcards

(49 cards)

1
Q

How is cardiac muscle nucleated

A

single mono nucleated cells

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2
Q

How is the nuclei of cardiac cells positioned

A

Centrally

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3
Q

Does cardiac tissue have a sarcomeric arrangement

A

Yes

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4
Q

Cardiac muscle tissue cells communicate via

A

Gap Junctions

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5
Q

What are the gap junctions in cardiac muscle cells

A

intercalated discs

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6
Q

Are cardiac muscle tissues directly innervated

A

No

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7
Q

Are the T-Tubules as extensive as those in skeletal muscle

A

No

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8
Q

Each T-tubule in cardiac muscles interacts with

A

one cisterna (rather than two as in skeletal muscle)

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9
Q

Cardiac muscle tissues T-Tubules form a

A

Diad

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10
Q

Where are the diads of cardiac muscles located

A

at the level of the Z-lines

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11
Q

What is the composition of Intercalated disks

A

Macula adherentes (desmosomes)
Fascia adherentes
Gap junction

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12
Q

What link intermediate filaments (desmin) of adjoining cardiac muscle cells

A

Macula adherentes (desmosomes)

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13
Q

The macula adherentes (desmosomes) are part of _______ component of intercalated disk

A

Transverse

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14
Q

Fascia adherentes anchor _____ filaments of sarcomeres in intercalated disks

A

actin

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15
Q

Fascia adherentes are part of _____ component of intercalated disks

A

Transverse

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16
Q

The gap junctions are part of the ______ component in intercalated disks

A

Longitudinal

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17
Q

Atrial Natriuretic Peptides (ANP) is secreted by

A

cardiac cells in the atria

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18
Q

Atrial natriuretic peptides (ANP) regulate what

A

fluid electrolyte balance

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19
Q

Atrial natriuretic peptides (ANP) relax what

A

vascular smooth muscle

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20
Q

The main function of Atrial Natriuretic Peptides (ANP)

A

reduces blood volume and BP

21
Q

Where is Atrial Natriuretic Peptide (ANP) stored and as what

A

In secretory vesicles stored as prohormone

22
Q

When is atrial natriuretic peptide released

A

release is stimulated by atrial stretch

- results in cleavage of prohormone

23
Q

What are synonyms of smooth muscle tissue

A

Involuntary

Visceral

24
Q

Smooth muscle tissue is what nucleation

A

mononucleated

25
Where is the nucleus of smooth muscle tissue located
Central nuclei
26
Does smooth muscle tissue have a sarcomeric arrangement
No
27
Smooth muscle tissue is innervated via what
ANS or Enteric system
28
Does smooth muscle tissue respond "all or nothing"
No
29
How are smooth muscle tissues connected
via gap junctions
30
In smooth muscle cells ___ and ____ bundles are incorporated into a meshwork arrangement
actin and myosin
31
Where are the actin and myosin bundles incorporated in smooth muscle cells
Found throughout cytoplasm except in nuclear area
32
Do smooth muscle cells have dense bodies
yes
33
What anchor actin filaments to each other and to cell membrane of smooth muscle cells
Dense bodies
34
Dense bodies of smooth muscle cells contain what
Alpha-actinin
35
Dense bodies are interconnected by what
a specific type of desmin
36
What communicate force of contraction to cytoskeleton and cell membrane of smooth muscle cells
Dense Bodies
37
Where are dense bodies of smooth muscle cells found
in cytoplasm and in the cell membrane
38
Do smooth muscle cells have a T-Tubule system or extensive SR
No
39
Where do smooth muscle cells get calcium
They are dependent on extracellular calcium concentration
40
What may transport calcium ions from extracellular fluids to sarcoplasmic reticulum of smooth muscle cells
Pinocytotic Vesicles
41
Lipid rafts are composed of what
cholesterol and sphingolipids
42
Caveolin binds to what ______ in lipid rafts and initiates the formation of what
Cholesterol, Caveolae
43
What are Caveolae
permanet depressions of the cell membrane that are involved in fluid and electrolyte transport
44
Vesicles that are formed detach and participate in what
vesicular trafficking
45
Innervation fo smooth muscles may either ____ or _____ contraction of the muscle cells
facilitate, inhibit
46
Adrenergic and muscarinic receptors are linked to what
G-proteins
47
Nicotininc cholinergic receptors
cation channel
48
Smooth muscle sheets of most major organs are what
poorly innervated
49
Excitation in smooth muscles is spread through numerous what
gap junctions