Cardio: Antidysrhythmic Drugs Flashcards

(48 cards)

1
Q

How does Atropine increase HR?

What receptors does it act on?

A
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2
Q

What are the Class III drugs?

A
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3
Q

Give the Clinical Application of Verapamil

A

Note: More useful than digoxin for rate control in atrial fibrillation due to the Ca+2 channel blockade in AV node persisting during sympathetic stimulation.

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4
Q

Give the PKs and ADRs for Propranolol

A
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5
Q

What is the general mechanism of Class Ib drugs?

What happens to phase 3, APD, and QT?

What conditions are they useful in treating?

A
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6
Q

What are the Class IV Agents?

A
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7
Q

What is the Class II Agent?

A

Propranolol

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8
Q

What are the Class Ia Agents?

A
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9
Q

Describe the PKs of Procainamide

A
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10
Q

What is Ventricular Re-entry, and what kind of Disorders of Impulse is it?

A

Disorder of Impulse Conduction

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11
Q

What are the ADRs Quinidine?

A
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12
Q

Label each action potential as either

  • Atrium
  • Ventricle
  • SA node
  • AV Node
  • Purkinje Fibers
A
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13
Q

What are the Pharmacokinetics for Digoxin?

A
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14
Q

Give each of the following the title as

  • ST segment
  • P Wave
  • QT Interval
  • QRS Complex
  • T Wave
  • PR Interval
A
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15
Q

What are the General mechanisms for Class II drugs?

A
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16
Q

Concerning AV Nodal Blocks, describe the difference in 1st, 2nd and third degree. What kind of Disorders of Impulse are they?

A
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17
Q
  • What is the mechanism for Lidocaine?
  • What is Lidocaine used to treat?
  • What does Lidocaine do to the ERP and APD?
A
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18
Q

Concerning Class Ic drugs

  • What happens to QRS, APD, QT, and PR?
  • What happens to phase 0?
  • What is special about the mechanism kinetics?
A
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19
Q

What are the ADRs for Amiodarone?

A
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20
Q

What is the general mechanism for all Class I Antidysrhythmic drugs?

A

Block voltage-sensitive Na+ channels

21
Q

Concerning Quinidine

  • What Clinical Applications does it have?
  • What does it do to the QRS and QT?
22
Q

What are the main Ventricular (alliterations at the ventricle muscle mass) Dysrhythmias?

23
Q

What are the ADRs for Verapamil?

24
Q

What does the Cardiac Action Potential look like for the Atria, Purkinje fibers, and Ventricles?

What about the SA and AV nodes?

25
What are the PKs of Lidocaine?
26
Describe the general mechanism of Verapamil * What does it do to HR, SA automaticity, PR, AV conduction, CO, and ventricular contractility?
27
Describe what Flecainide does to cardiac conduction, and the Clinical Applications for it
28
Give the PKs for Verapamil
29
What are the three major Consequences of Dysrhythmia?
30
* What is the general mechanism for Class Ia Antidysrhythmic drugs? * What do they do phase 0? phase 2? phase 3? How? * What happens to QRS and QT?
31
What are the ADRs for Digoxin?
32
Concerning the Causative Mechanisms for Dysrhythmia Generation, describe Disorders of Impulse Formation.
33
What are the ADRs of Procainamide?
34
Concerning Ibutilide * What is different about its mechanism compared to other drugs of the same class? * What effect does it have on MAP, HR, QRS, and PR? * What is notable about its PKs?
35
What is Sotalol used to treat and channel does it effect that is unique among other NS Beta Blockers?
36
Concerning Class III Agents * Give the general mechanism * What they do to phase 3 and QT * What they are generally useful for
37
How do you manage Sinus Tachycardia?
38
What kind of Disorders of Impulse are DADs or Delayed After- Depolarizations?
39
What are the Clinical Applications for Digoxin? * What does it do to Na+/K+-ATPase? * What happens to ERP? * What happens to P-wave depolarizations?
40
What are the main Supraventricular (alliterations at or above the level of the AV NODE) Dysrhythmias?
41
Give the general effects and Clinical Applications for Propranolol
42
What condition is Diltiazem useful for?
43
Give the PKs for Amiodarone
44
Concerning Amiodarone * What is the general mechanism * What does it do to ERP and APD * What the Clinical Applications
45
Concerning Class IV Agents * Give the general mechanism * What it does to the SA Node and AV Node, and ventricular contractility
46
What are the Class 5 drugs?
47
What is Digoxin?
Class 5 Antidysrhythmic Cardiac Glycoside
48
Compare Verapamil and digoxin for use in controlling A-Fib.