Cardio: Antihypertensive Drugs Flashcards

(39 cards)

1
Q

Describe how α-Methyldopa works and its ADRs

A
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2
Q

What are the uses of Minoxidil?

A
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3
Q

Describe the efficacy and PKs for Reserpine

A
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4
Q

Describe the MOA and for Efficacy propranolol

A
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5
Q

Describe the MOA and PK s for [Verapamil + diltiazem]

A
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6
Q

Describe the general PKs of Diuretics

A
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7
Q

Describe the Tolerance development seen in Hydralazine use?

A
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8
Q

What are the ADRs/contraindications for Diuretics?

A
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9
Q

What group of drugs does the following describe?

A
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10
Q

Describe the PKs for ACE INHIBITORS

A
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11
Q

List and describe the two major types of Hypertension

A
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12
Q

Describe the general mechanisms of Diuretics

A
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13
Q

What is the MOA and ADRs for Sodium nitroprusside?

A
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14
Q

What are the two Centrally-acting sympatholytics?

A

Clonidine

α-Methyldopa

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15
Q

What is the MOA for Minoxidil?

A
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16
Q

Describe the PKs and ADRs for propranolol

17
Q

What are the Peripherally-acting sympatholytics?

A

Reserpine + the alpha-1 blockers (Prazosin, terazosin, doxazosin)

18
Q

Describe the MOA for Reserpine

19
Q

What is MOA for all drugs that end with -sartan?

20
Q

What are the ADR for Reserpine?

21
Q

When would you use Diuretics?

  • Who do they work best on?
22
Q

What are the Direct-acting vasodilators?

A

Hydralazine

Minoxidil

Sodium nitroprusside

23
Q

Describe the ADRs for ACE INHIBITORS

24
Q

Describe the MOA and Efficacy for Clonidine

25
What are the benefits and ADRs for [Prazosin, terazosin, doxazosin]?
26
What does Chronic hypertension do to the baroreceptor reflex?
27
What is Endothelin and how does it work?
28
* What is hypertension defined as?
29
Describe the MOA, Efficacy, and ADRs for Nifedipine
30
Describe what EDRF is and how it works
31
Describe the Efficacy and ADRs for [Verapamil + diltiazem]
32
What are the three main classes of Diuretics?
33
Describe how angiotensinogen eventually affects blood vessel size and aldosterone
34
What are the Calcium channel antagonists?
[Verapamil + diltiazem] + Nifedipine (part of the Dihydropyridine class of CCB)
35
What are the ADRs of Hydralazine?
36
What are the ADRs for Angiotensin receptor blockers?
37
What are the Lifestyle (Non-Pharmacological) Modifications for Hypertension?
38
What is Sodium nitroprusside used for? What does it do to afterload and preload?
39
Describe the MOA and efficacy for [Prazosin, terazosin, doxazosin]